5DOF
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![BU of 5dof by Molmil](/molmil-images/mine/5dof) | Crystal structure of Tetrahymena p19 | Descriptor: | Telomerase-associated protein 19 | Authors: | Wan, B, Tang, T, Wu, J, Lei, M. | Deposit date: | 2015-09-11 | Release date: | 2015-11-25 | Last modified: | 2015-12-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex. Nat.Struct.Mol.Biol., 22, 2015
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5WQD
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5F59
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![BU of 5f59 by Molmil](/molmil-images/mine/5f59) | The crystal structure of MLL3 SET domain | Descriptor: | Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | Authors: | Li, Y, Lei, M, Chen, Y. | Deposit date: | 2015-12-04 | Release date: | 2016-02-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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5F6L
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![BU of 5f6l by Molmil](/molmil-images/mine/5f6l) | The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L | Descriptor: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Li, Y, Lei, M, Chen, Y. | Deposit date: | 2015-12-06 | Release date: | 2016-02-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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5F5E
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5F6K
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![BU of 5f6k by Molmil](/molmil-images/mine/5f6k) | Crystal structure of the MLL3-Ash2L-RbBP5 complex | Descriptor: | Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Li, Y, Lei, M, Chen, Y. | Deposit date: | 2015-12-06 | Release date: | 2016-02-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.411 Å) | Cite: | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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7V99
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![BU of 7v99 by Molmil](/molmil-images/mine/7v99) | catalytic core of human telomerase holoenzyme | Descriptor: | Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ... | Authors: | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2021-08-24 | Release date: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Zipper head mechanism of telomere synthesis by human telomerase. Cell Res., 31, 2021
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7V9A
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![BU of 7v9a by Molmil](/molmil-images/mine/7v9a) | biogenesis module of human telomerase holoenzyme | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | Authors: | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2021-08-24 | Release date: | 2022-03-30 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Zipper head mechanism of telomere synthesis by human telomerase. Cell Res., 31, 2021
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4ZMI
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![BU of 4zmi by Molmil](/molmil-images/mine/4zmi) | Crystal structure of the Helical domain of S. pombe Taz1 | Descriptor: | COBALT (II) ION, MAGNESIUM ION, Telomere length regulator taz1 | Authors: | Deng, W, Wu, J, Wang, F, Lei, M. | Deposit date: | 2015-05-04 | Release date: | 2015-09-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2. Cell Res., 25, 2015
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4ZOU
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4ZMK
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2SRC
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![BU of 2src by Molmil](/molmil-images/mine/2src) | CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TYROSINE-PROTEIN KINASE SRC | Authors: | Xu, W, Doshi, A, Lei, M, Eck, M.J, Harrison, S.C. | Deposit date: | 1998-12-29 | Release date: | 1999-07-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol.Cell, 3, 1999
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3KF6
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![BU of 3kf6 by Molmil](/molmil-images/mine/3kf6) | Crystal structure of S. pombe Stn1-ten1 complex | Descriptor: | Protein stn1, Protein ten1 | Authors: | Sun, J, Yu, E.Y, Yang, Y.T, Confer, L.A, Sun, S.H, Wan, K, Lue, N.F, Lei, M. | Deposit date: | 2009-10-27 | Release date: | 2009-12-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres. Genes Dev., 23, 2009
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3L82
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![BU of 3l82 by Molmil](/molmil-images/mine/3l82) | X-ray Crystal structure of TRF1 and Fbx4 complex | Descriptor: | F-box only protein 4, Telomeric repeat-binding factor 1 | Authors: | Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M. | Deposit date: | 2009-12-29 | Release date: | 2010-03-09 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4) Dev.Cell, 18, 2010
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3KEY
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![BU of 3key by Molmil](/molmil-images/mine/3key) | Crystal structure of S. cerevisiae Stn1 C-terminal | Descriptor: | Protein STN1 | Authors: | Sun, J, Yu, E.Y, Yang, Y.T, Confer, L.A, Sun, S.H, Wan, K, Lue, N.F, Lei, M. | Deposit date: | 2009-10-26 | Release date: | 2009-12-22 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres. Genes Dev., 23, 2009
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3KF8
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![BU of 3kf8 by Molmil](/molmil-images/mine/3kf8) | Crystal structure of C. tropicalis Stn1-ten1 complex | Descriptor: | Protein stn1, Protein ten1 | Authors: | Sun, J, Yu, E.Y, Yang, Y.T, Confer, L.A, Sun, S.H, Wan, K, Lue, N.F, Lei, M. | Deposit date: | 2009-10-27 | Release date: | 2009-12-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres. Genes Dev., 23, 2009
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3NBI
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![BU of 3nbi by Molmil](/molmil-images/mine/3nbi) | Crystal structure of human RMI1 N-terminus | Descriptor: | RecQ-mediated genome instability protein 1 | Authors: | Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. | Deposit date: | 2010-06-03 | Release date: | 2010-09-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex. Structure, 18, 2010
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3NBH
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![BU of 3nbh by Molmil](/molmil-images/mine/3nbh) | Crystal structure of human RMI1C-RMI2 complex | Descriptor: | RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | Authors: | Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. | Deposit date: | 2010-06-03 | Release date: | 2010-09-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex. Structure, 18, 2010
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3OIQ
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![BU of 3oiq by Molmil](/molmil-images/mine/3oiq) | Crystal structure of yeast telomere protein Cdc13 OB1 and the catalytic subunit of DNA polymerase alpha Pol1 | Descriptor: | Cell division control protein 13, DNA polymerase alpha catalytic subunit A | Authors: | Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. | Deposit date: | 2010-08-19 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha. Cell Res., 21, 2011
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3OWT
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![BU of 3owt by Molmil](/molmil-images/mine/3owt) | Crystal structure of S. cerevisiae RAP1-Sir3 complex | Descriptor: | DNA-binding protein RAP1, Regulatory protein SIR3 | Authors: | Chen, Y, Yang, Y, Lei, M. | Deposit date: | 2010-09-20 | Release date: | 2011-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms. Nat.Struct.Mol.Biol., 18, 2011
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3OIP
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![BU of 3oip by Molmil](/molmil-images/mine/3oip) | Crystal structure of Yeast telomere protein Cdc13 OB1 | Descriptor: | Cell division control protein 13 | Authors: | Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. | Deposit date: | 2010-08-19 | Release date: | 2010-11-03 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.504 Å) | Cite: | Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha. Cell Res., 21, 2011
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6AHV
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![BU of 6ahv by Molmil](/molmil-images/mine/6ahv) | Crystal structure of human RPP40 | Descriptor: | Ribonuclease P protein subunit p40 | Authors: | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | Deposit date: | 2018-08-20 | Release date: | 2018-12-05 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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4O26
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3RSN
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![BU of 3rsn by Molmil](/molmil-images/mine/3rsn) | Crystal Structure of the N-terminal region of Human Ash2L | Descriptor: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | Authors: | Chen, Y, Wan, B, Wang, K.C, Cao, F, Yang, Y, Protacio, A, Dou, Y, Chang, H.Y, Lei, M. | Deposit date: | 2011-05-02 | Release date: | 2011-06-22 | Last modified: | 2011-12-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Rep., 12, 2011
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6AHU
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![BU of 6ahu by Molmil](/molmil-images/mine/6ahu) | Cryo-EM structure of human Ribonuclease P with mature tRNA | Descriptor: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | Authors: | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | Deposit date: | 2018-08-20 | Release date: | 2018-12-05 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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