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6BXC
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BU of 6bxc by Molmil
Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 9 (VLR9) bound
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R.
Deposit date:2017-12-18
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies.
J. Mol. Biol., 430, 2018
3CFB
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BU of 3cfb by Molmil
High-resolution structure of blue fluorescent antibody EP2-19G2 in complex with stilbene hapten at 100K
Descriptor: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, BLUE FLUORESCENT ANTIBODY EP2-19G2-IGG2B HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY EP2-19G2-KAPPA LIGHT CHAIN, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-03-03
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
6BKR
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BU of 6bkr by Molmil
Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin in complex with 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
6CXG
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BU of 6cxg by Molmil
anti-HIV-1 Fab 2G12 in complex with glycopeptide 10V1S
Descriptor: 10V1S glycopeptide, GLYCEROL, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2018-04-03
Release date:2019-02-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.
ACS Cent Sci, 5, 2019
3GBM
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BU of 3gbm by Molmil
Crystal Structure of Fab CR6261 in Complex with a H5N1 influenza virus hemagglutinin.
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ekiert, D.C, Elsliger, M.A, Wilson, I.A.
Deposit date:2009-02-20
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Antibody recognition of a highly conserved influenza virus epitope.
Science, 324, 2009
4N62
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BU of 4n62 by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a sulfated receptor analog
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2013-10-11
Release date:2013-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5026 Å)
Cite:Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4N60
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BU of 4n60 by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2013-10-11
Release date:2013-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9032 Å)
Cite:Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4MAS
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BU of 4mas by Molmil
High Resolution Structure of Wild Type Human Transthyretin in Complex with 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol
Descriptor: 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL, Transthyretin
Authors:Connelly, S, Bradbury, N.C, Wilson, I.A.
Deposit date:2013-08-16
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:High Resolution Structure of Wild Type Human Transthyretin in Complex with 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol
To be Published
3FO1
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BU of 3fo1 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Ala mutant)
Descriptor: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-12-27
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3FO2
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BU of 3fo2 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Gln mutant)
Descriptor: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2008-12-27
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3GBN
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BU of 3gbn by Molmil
Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin
Descriptor: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ekiert, D.C, Elsliger, M.A, Wilson, I.A.
Deposit date:2009-02-20
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antibody recognition of a highly conserved influenza virus epitope.
Science, 324, 2009
4QDH
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BU of 4qdh by Molmil
Crystal Structure of the C-terminal Domain of Mouse TLR9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ...
Authors:Collins, B.C, Wilson, I.A.
Deposit date:2014-05-13
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal structure of the C-terminal domain of mouse TLR9.
Proteins, 82, 2014
3GMR
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BU of 3gmr by Molmil
Structure of mouse CD1d in complex with C8Ph, different space group
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
3GMM
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BU of 3gmm by Molmil
Structure of mouse CD1d in complex with C8Ph
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ...
Authors:Schiefner, A, Wilson, I.A.
Deposit date:2009-03-14
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands.
J.Mol.Biol., 394, 2009
1ED3
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BU of 1ed3 by Molmil
CRYSTAL STRUCTURE OF RAT MINOR HISTOCOMPATIBILITY ANTIGEN COMPLEX RT1-AA/MTF-E.
Descriptor: BETA-2-MICROGLOBULIN, CLASS I MAJOR HISTOCOMPATIBILITY ANTIGEN RT1-AA, PEPTIDE MTF-E (13N3E)
Authors:Speir, J.A, Stevens, J, Joly, E, Butcher, G.W, Wilson, I.A.
Deposit date:2000-01-26
Release date:2001-02-28
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Two different, highly exposed, bulged structures for an unusually long peptide bound to rat MHC class I RT1-Aa.
Immunity, 14, 2001
1G7Q
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BU of 1g7q by Molmil
CRYSTAL STRUCTURE OF MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND MUC1 VNTR PEPTIDE SAPDTRPA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-2 MICROGLOBULIN, ...
Authors:Apostolopoulos, V, Yu, M, Corper, A.L, Teyton, L, Pietersz, G.A, McKenzie, I.F, Wilson, I.A.
Deposit date:2000-11-13
Release date:2002-07-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.
J.Mol.Biol., 318, 2002
1G7P
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BU of 1g7p by Molmil
CRYSTAL STRUCTURE OF MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-GLUCOSIDASE P1, ...
Authors:Apostolopoulos, V, Yu, M, Corper, A.L, Li, W, McKenzie, I.F, Teyton, L, Wilson, I.A.
Deposit date:2000-11-13
Release date:2002-07-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors.
J.Mol.Biol., 318, 2002
1FGN
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BU of 1fgn by Molmil
MONOCLONAL MURINE ANTIBODY 5G9-ANTI-HUMAN TISSUE FACTOR
Descriptor: IMMUNOGLOBULIN FAB 5G9
Authors:Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A.
Deposit date:1997-04-10
Release date:1998-02-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.5G9 complex.
J.Mol.Biol., 275, 1998
1FIG
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BU of 1fig by Molmil
ROUTES TO CATALYSIS: STRUCTURE OF A CATALYTIC ANTIBODY AND COMPARISON WITH ITS NATURAL COUNTERPART
Descriptor: 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, IGG1-KAPPA 1F7 FAB (HEAVY CHAIN), IGG1-KAPPA 1F7 FAB (LIGHT CHAIN)
Authors:Haynes, M.R, Stura, E.A, Hilvert, D, Wilson, I.A.
Deposit date:1994-01-07
Release date:1994-05-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart.
Science, 263, 1994
1FZM
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BU of 1fzm by Molmil
MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
Deposit date:2000-10-03
Release date:2001-03-28
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001
1FZK
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BU of 1fzk by Molmil
MHC CLASS I NATURAL MUTANT H-2KBM1 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
Deposit date:2000-10-03
Release date:2001-03-28
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001
1G8M
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BU of 1g8m by Molmil
CRYSTAL STRUCTURE OF AVIAN ATIC, A BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME IN PURINE BIOSYNTHESIS AT 1.75 ANG. RESOLUTION
Descriptor: AICAR TRANSFORMYLASE-IMP CYCLOHYDROLASE, GUANOSINE-5'-MONOPHOSPHATE, POTASSIUM ION
Authors:Greasley, S.E, Horton, P, Beardsley, G.P, Benkovic, S.J, Wilson, I.A.
Deposit date:2000-11-17
Release date:2001-04-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.
Nat.Struct.Biol., 8, 2001
1ES0
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BU of 1es0 by Molmil
CRYSTAL STRUCTURE OF THE MURINE CLASS II ALLELE I-A(G7) COMPLEXED WITH THE GLUTAMIC ACID DECARBOXYLASE (GAD65) PEPTIDE 207-220
Descriptor: 65 KD GLUTAMIC ACID DECARBOXYLASE+H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN
Authors:Corper, A.L, Teyton, L, Wilson, I.A.
Deposit date:2000-04-07
Release date:2000-06-28
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes.
Science, 288, 2000
1FZO
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BU of 1fzo by Molmil
MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
Deposit date:2000-10-03
Release date:2001-03-28
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001
1FZJ
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BU of 1fzj by Molmil
MHC CLASS I NATURAL MUTANT H-2KBM1 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
Deposit date:2000-10-03
Release date:2001-03-28
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001

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