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4KIP
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BU of 4kip by Molmil
Crystal structure of mitogen-activated protein kinase 14 (P38-H5) complex with 2-(2-CHLOROPHENYL)-N-(5-(CYCLOPROPYLCARBAMOYL)-2-METHYLPHENYL)-1,3-THIAZOLE-5-CARBOXAMIDE
Descriptor: 2-(2-chlorophenyl)-N-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-1,3-thiazole-5-carboxamide, Mitogen-activated protein kinase 14
Authors:Sack, J.S, Tokarski, J.S.
Deposit date:2013-05-02
Release date:2013-06-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:The Identification of Novel P38-Alpha Isoform Selective Kinase Inhibitors Having an Unprecedented P38-Alpha Binding Mode
Bioorg.Med.Chem.Lett., 23, 2013
4QQW
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BU of 4qqw by Molmil
Crystal structure of T. fusca Cas3
Descriptor: CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.664 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4NAA
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BU of 4naa by Molmil
Crystal structure of UVB photoreceptor UVR8 from Arabidopsis thaliana and UV-induced structural changes at 120K
Descriptor: MAGNESIUM ION, Ultraviolet-B receptor UVR8
Authors:Yang, X, Zeng, X, Ren, Z, Zhao, K.H.
Deposit date:2013-10-22
Release date:2016-10-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.
Nat Plants, 1, 2015
4NBM
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BU of 4nbm by Molmil
Crystal structure of UVB photoreceptor UVR8 and light-induced structural changes at 180K
Descriptor: MAGNESIUM ION, Ultraviolet-B receptor UVR8
Authors:Yang, X, Zeng, X, Zhao, K.-H, Ren, Z.
Deposit date:2013-10-23
Release date:2016-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.
Nat Plants, 1, 2015
4KS7
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BU of 4ks7 by Molmil
PAK6 kinase domain in complex with PF-3758309
Descriptor: ISOPROPYL ALCOHOL, PF-3758309, Serine/threonine-protein kinase PAK 6
Authors:Gao, J, Boggon, T.J.
Deposit date:2013-05-17
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6.
Plos One, 8, 2013
4QQX
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BU of 4qqx by Molmil
Crystal structure of T. fusca Cas3-ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4NC4
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BU of 4nc4 by Molmil
Crystal structure of photoreceptor AtUVR8 mutant W285F and light-induced structural changes at 120K
Descriptor: MAGNESIUM ION, Ultraviolet-B receptor UVR8
Authors:Yang, X, Zeng, X, Zhao, K.-H, Ren, Z.
Deposit date:2013-10-23
Release date:2016-10-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8.
Nat Plants, 1, 2015
4QQZ
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BU of 4qqz by Molmil
Crystal structure of T. fusca Cas3-AMPPNP
Descriptor: CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4QQY
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BU of 4qqy by Molmil
Crystal structure of T. fusca Cas3-ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4NCC
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BU of 4ncc by Molmil
Neutralizing antibody to murine norovirus
Descriptor: Fab fragment heavy, Fab fragment light
Authors:Smith, T, Li, M.
Deposit date:2013-10-24
Release date:2014-02-19
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization.
J.Virol., 88, 2014
4O26
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BU of 4o26 by Molmil
Crystal structure of the TRBD domain of TERT and the CR4/5 of TR
Descriptor: SULFATE ION, Telomerase TR, Telomerase reverse transcriptase
Authors:Huang, J, Wu, J, Lei, M.
Deposit date:2013-12-16
Release date:2014-05-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Structural basis for protein-RNA recognition in telomerase.
Nat.Struct.Mol.Biol., 21, 2014
3BAX
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BU of 3bax by Molmil
N298S Variant of Human Pancreatic Alpha-Amylase in Complex with Azide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, CALCIUM ION, ...
Authors:Maurus, R, Brayer, G.D.
Deposit date:2007-11-08
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAY
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BU of 3bay by Molmil
N298S Variant of Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, CALCIUM ION, ...
Authors:Fredriksen, J.R, Maurus, R, Brayer, G.D.
Deposit date:2007-11-08
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAW
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BU of 3baw by Molmil
Human pancreatic alpha-amylase complexed with azide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, CALCIUM ION, ...
Authors:Maurus, R, Brayer, G.D.
Deposit date:2007-11-08
Release date:2008-03-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAK
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BU of 3bak by Molmil
N298S mutant of Human Pancreatic Alpha-Amylase in complex with nitrate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRATE ION, ...
Authors:Fredriksen, J.R, Maurus, R, Brayer, G.D.
Deposit date:2007-11-08
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAJ
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BU of 3baj by Molmil
Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, CALCIUM ION, ...
Authors:Fredriksen, J.R, Maurus, R, Brayer, G.D.
Deposit date:2007-11-07
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
3BAI
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BU of 3bai by Molmil
Human Pancreatic Alpha Amylase with Bound Nitrate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRATE ION, ...
Authors:Fredriksen, J.R, Maurus, R, Brayer, G.D.
Deposit date:2007-11-07
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
4G2Y
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BU of 4g2y by Molmil
Crystal structure of PDE5A complexed with its inhibitor
Descriptor: 2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Ren, J, Chen, T.T, Xu, Y.C.
Deposit date:2012-07-13
Release date:2013-06-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5.
J.Med.Chem., 55, 2012
5X1G
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BU of 5x1g by Molmil
WHAMM's Microtubule binding motif
Descriptor: WASP homolog-associated protein with actin, membranes and microtubules
Authors:Liu, T, Wang, H.W.
Deposit date:2017-01-25
Release date:2017-07-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural Insights of WHAMM's Interaction with Microtubules by Cryo-EM
J. Mol. Biol., 429, 2017
4HKB
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BU of 4hkb by Molmil
CH67 Fab (unbound) from the CH65-67 Lineage
Descriptor: CH67 heavy chain, CH67 light chain
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-15
Release date:2012-11-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HK3
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BU of 4hk3 by Molmil
I2 Fab (unbound) from CH65-CH67 Lineage
Descriptor: I2 heavy chain, I2 light chain
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-14
Release date:2012-11-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HKX
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BU of 4hkx by Molmil
Influenza hemagglutinin in complex with CH67 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CH67 heavy chain, CH67 light chain, ...
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-15
Release date:2012-11-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HK0
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BU of 4hk0 by Molmil
UCA Fab (unbound) from CH65-CH67 Lineage
Descriptor: UCA heavy chain, UCA light chain
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-14
Release date:2012-11-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
5ZB7
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BU of 5zb7 by Molmil
CTX-M-64 apoenzyme
Descriptor: Beta-lactamase
Authors:Cheng, Q, Chen, S.
Deposit date:2018-02-10
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural Insight into the Mechanism of Inhibitor Resistance in CTX-M-199, a CTX-M-64 Variant Carrying the S130T Substitution.
Acs Infect Dis., 6, 2020
3NRT
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BU of 3nrt by Molmil
The crystal structure of putative ryanodine receptor from Bacteroides thetaiotaomicron VPI-5482
Descriptor: GLYCEROL, MAGNESIUM ION, Putative ryanodine receptor
Authors:Wu, R, Zhang, R, James, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-06-30
Release date:2010-09-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:he crystal strucutre of putative ryanodine receptor from Bacteroides thetaiotaomicron VPI-5482
To be Published

223790

PDB entries from 2024-08-14

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