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1DYI
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BU of 1dyi by Molmil
ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
Descriptor: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
Authors:Reyes, V.M, Kraut, J.
Deposit date:1994-10-26
Release date:1995-06-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34, 1995
7UAK
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BU of 7uak by Molmil
Structure of recombinantly assembled A53E alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Zhou, K, Zhou, H.
Deposit date:2022-03-13
Release date:2023-03-29
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Cryo-EM structure of amyloid fibril formed by alpha-synuclein hereditary A53E mutation reveals a distinct protofilament interface.
J.Biol.Chem., 299, 2023
4XFO
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BU of 4xfo by Molmil
Structure of an amyloid-forming segment TAVVTN from human Transthyretin
Descriptor: Amyloid-forming peptide TAVVTN
Authors:Saelices, L, Sawaya, M, Cascio, D, Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4XFN
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BU of 4xfn by Molmil
Structure of an Amyloid forming peptide AEVVFT from Human Transthyretin
Descriptor: Amyloid forming peptide AEVVFT
Authors:Saelices, L, Sawaya, M, Cascio, D, Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4YAY
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BU of 4yay by Molmil
XFEL structure of human Angiotensin Receptor
Descriptor: 5,7-diethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-1,6-naphthyridin-2(1H)-one, Soluble cytochrome b562,Type-1 angiotensin II receptor
Authors:Zhang, H, Unal, H, Gati, C, Han, G.W, Zatsepin, N.A, James, D, Wang, D, Nelson, G, Weierstall, U, Messerschmidt, M, Williams, G.J, Boutet, S, Yefanov, O.M, White, T.A, Liu, W, Ishchenko, A, Tirupula, K.C, Desnoyer, R, Sawaya, M.C, Xu, Q, Coe, J, Cornrad, C.E, Fromme, P, Stevens, R.C, Katritch, V, Karnik, S.S, Cherezov, V, GPCR Network (GPCR)
Deposit date:2015-02-18
Release date:2015-04-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.
Cell, 161, 2015
5E5Z
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BU of 5e5z by Molmil
Structure of the amyloid forming peptide LVHSSN (residues
Descriptor: LVHSSN (residues 16-21) from islet amyloid polypeptide
Authors:Soriaga, A.B, Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.664 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E61
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BU of 5e61 by Molmil
Structure of amyloid-forming peptide FGAILSS (residues 23-29) from islet amyloid polypeptide
Descriptor: FGAILSS (residues 23-29) from islet amyloid polypeptide
Authors:Soriaga, A.B, Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
6I9J
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BU of 6i9j by Molmil
Human transforming growth factor beta2 in a tetragonal crystal form
Descriptor: Transforming growth factor beta-2 proprotein
Authors:Gomis-Ruth, F.X, Marino-Puertas, L, del Amo-Maestro, L, Goulas, T.
Deposit date:2018-11-23
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation.
Sci Rep, 9, 2019
4GZR
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BU of 4gzr by Molmil
Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221
Descriptor: ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION
Authors:Arbing, M.A, Chan, S, He, Q, Harris, L, Zhou, T.T, Kuo, E, Ahn, C.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2012-09-06
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.553 Å)
Cite:Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
4I0X
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BU of 4i0x by Molmil
Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex
Descriptor: BETA-MERCAPTOETHANOL, ESAT-6-like protein MAB_3112, ESAT-6-like protein MAB_3113, ...
Authors:Arbing, M.A, Chan, S, Lu, J, Kuo, E, Harris, L, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
Deposit date:2012-11-19
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.956 Å)
Cite:Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
7QX4
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BU of 7qx4 by Molmil
mosquitocidal Cry11Aa determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX6
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BU of 7qx6 by Molmil
mosquitocidal Cry11Aa-E583Q determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX5
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BU of 7qx5 by Molmil
mosquitocidal Cry11Aa-Y449F determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX7
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BU of 7qx7 by Molmil
mosquitocidal Cry11Aa-F17Y determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
5W7V
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BU of 5w7v by Molmil
CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Ge, P, Eisenberg, D.S.
Deposit date:2017-06-20
Release date:2018-03-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
5E5X
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BU of 5e5x by Molmil
Structure of the amyloid forming peptide ANFLVH (residues 13-18) from islet amyloid polypeptide
Descriptor: ANFLVH (residues 13-18) from islet amyloid polypeptide
Authors:Soriaga, A.B, Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
4L4W
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BU of 4l4w by Molmil
Structure of EspG3 chaperone from the type VII (ESX-3) secretion system
Descriptor: EspG3
Authors:Korotkov, K.V.
Deposit date:2013-06-09
Release date:2014-06-11
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.036 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
3LE4
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BU of 3le4 by Molmil
Crystal structure of the DGCR8 dimerization domain
Descriptor: Microprocessor complex subunit DGCR8
Authors:Senturia, R, Cascio, D, Sawaya, M, Guo, F.
Deposit date:2010-01-14
Release date:2010-07-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Structure of the dimerization domain of DiGeorge Critical Region 8
Protein Sci., 19, 2010
3LOZ
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BU of 3loz by Molmil
Crystal structure of Beta 2 Microglobulin amyloidogenic segment LSFSKD
Descriptor: Beta-2-microglobulin segment LSFSKD
Authors:Liu, C, Sawaya, M, Eisenberg, D.
Deposit date:2010-02-04
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Beta2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages.
Nat.Struct.Mol.Biol., 18, 2011
1S3Q
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BU of 1s3q by Molmil
Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus
Descriptor: ZINC ION, ferritin
Authors:Johnson, E, Cascio, D, Sawaya, M, Schroeder, I.
Deposit date:2004-01-13
Release date:2005-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus.
Structure, 13, 2005
2CUU
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BU of 2cuu by Molmil
Crystal structure of spin labeled T4 Lysozyme (V131R1)
Descriptor: 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ...
Authors:Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L.
Deposit date:2005-05-28
Release date:2006-08-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural origin of weakly ordered nitroxide motion in spin-labeled proteins
Protein Sci., 18, 2009
1SQ3
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BU of 1sq3 by Molmil
Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus.
Descriptor: FE (III) ION, ferritin
Authors:Johnson, E, Cascio, D, Michael, S, Schroder, I.
Deposit date:2004-03-17
Release date:2005-04-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus.
Structure, 13, 2005
4TKW
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BU of 4tkw by Molmil
Crystal Structure of Human Transthyretin Leu55Pro Mutant
Descriptor: Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-27
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL4
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BU of 4tl4 by Molmil
Crystal Structure of Human Transthyretin Val30Met Mutant
Descriptor: Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TNE
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BU of 4tne by Molmil
Crystal Structure of Human Transthyretin Thr119Tyr Mutant
Descriptor: GLYCEROL, Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-06-03
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015

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