2XWS
| ANAEROBIC COBALT CHELATASE (CbiX) FROM ARCHAEOGLOBUS FULGIDUS | Descriptor: | SIROHYDROCHLORIN COBALTOCHELATASE | Authors: | Romao, C.V, Ladakis, D, Lobo, S.A.L, Carrondo, M.A, Brindley, A.A, Deery, E, Matias, P.M, Pickersgill, R.W, Saraiva, L.M, Warren, M.J. | Deposit date: | 2010-11-04 | Release date: | 2010-12-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Evolution in a Family of Chelatases Facilitated by the Introduction of Active Site Asymmetry and Protein Oligomerization. Proc.Natl.Acad.Sci.USA, 108, 2011
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1QGO
| ANAEROBIC COBALT CHELATASE IN COBALAMIN BIOSYNTHESIS FROM SALMONELLA TYPHIMURIUM | Descriptor: | ANAEROBIC COBALAMIN BIOSYNTHETIC COBALT CHELATASE, SULFATE ION | Authors: | Schubert, H.L, Raux, E, Warren, M.J, Wilson, K.S. | Deposit date: | 1999-05-03 | Release date: | 1999-09-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Common chelatase design in the branched tetrapyrrole pathways of heme and anaerobic cobalamin synthesis. Biochemistry, 38, 1999
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2CBF
| THE X-RAY STRUCTURE OF A COBALAMIN BIOSYNTHETIC ENZYME, COBALT PRECORRIN-4 METHYLTRANSFERASE, CBIF, FROM BACILLUS MEGATERIUM, WITH THE HIS-TAG CLEAVED OFF | Descriptor: | COBALT-PRECORRIN-4 TRANSMETHYLASE, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Schubert, H.L, Raux, E, Woodcock, S.C, Warren, M.J, Wilson, K.S. | Deposit date: | 1998-05-01 | Release date: | 1999-05-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase. Nat.Struct.Biol., 5, 1998
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1CBF
| THE X-RAY STRUCTURE OF A COBALAMIN BIOSYNTHETIC ENZYME, COBALT PRECORRIN-4 METHYLTRANSFERASE, CBIF | Descriptor: | COBALT-PRECORRIN-4 TRANSMETHYLASE, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Schubert, H.L, Raux, E, Woodcock, S.C, Wilson, K.S, Warren, M.J. | Deposit date: | 1998-05-01 | Release date: | 1999-05-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase. Nat.Struct.Biol., 5, 1998
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2QBU
| Crystal structure of Methanothermobacter thermautotrophicus CbiL | Descriptor: | Precorrin-2 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Frank, S, Warren, M.J, Pickersgill, R.W. | Deposit date: | 2007-06-18 | Release date: | 2008-04-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Elucidation of substrate specificity in the cobalamin (vitamin B12) biosynthetic methyltransferases. Structure and function of the C20 methyltransferase (CbiL) from Methanothermobacter thermautotrophicus. J.Biol.Chem., 282, 2007
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4CCS
| The structure of CbiX, the terminal Enzyme for Biosynthesis of Siroheme in Denitrifying Bacteria | Descriptor: | 1,2-ETHANEDIOL, CBIX, D-MALATE, ... | Authors: | Bali, S, Rollauer, S.E, Roversi, P, Raux-Deery, E, Lea, S.M, Warren, M.J, Ferguson, S.J. | Deposit date: | 2013-10-25 | Release date: | 2014-04-09 | Last modified: | 2015-09-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification and Characterization of the 'Missing' Terminal Enzyme for Siroheme Biosynthesis in Alpha-Proteobacteria. Mol.Microbiol., 92, 2014
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4CZD
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2W6L
| The crystal structure at 1.7 A resolution of CobE, a protein from the cobalamin (vitamin B12) biosynthetic pathway | Descriptor: | COBE, GLYCEROL, SULFATE ION | Authors: | Vevodova, J, Smith, D, McGoldrick, H, Deery, E, Murzin, A.G, Warren, M.J, Wilson, K.S. | Deposit date: | 2008-12-18 | Release date: | 2008-12-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway To be Published
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1PDA
| STRUCTURE OF PORPHOBILINOGEN DEAMINASE REVEALS A FLEXIBLE MULTIDOMAIN POLYMERASE WITH A SINGLE CATALYTIC SITE | Descriptor: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, ACETIC ACID, PORPHOBILINOGEN DEAMINASE | Authors: | Louie, G.V, Brownlie, P.D, Lambert, R, Cooper, J.B, Blundell, T.L, Wood, S.P, Warren, M.J, Woodcock, S.C, Jordan, P.M. | Deposit date: | 1992-11-17 | Release date: | 1993-10-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site. Nature, 359, 1992
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1PJS
| The co-crystal structure of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis, in complex with it NAD cofactor | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Stroupe, M.E, Leech, H.K, Daniels, D.S, Warren, M.J, Getzoff, E.D. | Deposit date: | 2003-06-03 | Release date: | 2003-12-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis. Nat.Struct.Biol., 10, 2003
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1PJQ
| Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis | Descriptor: | ACETATE ION, S-ADENOSYL-L-HOMOCYSTEINE, Siroheme synthase, ... | Authors: | Stroupe, M.E, Leech, H.K, Daniels, D.S, Warren, M.J, Getzoff, E.D. | Deposit date: | 2003-06-03 | Release date: | 2003-12-02 | Last modified: | 2014-11-12 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis. Nat.Struct.Biol., 10, 2003
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1PJT
| The structure of the Ser128Ala point-mutant variant of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis | Descriptor: | PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, Siroheme synthase | Authors: | Stroupe, M.E, Leech, H.K, Daniels, D.S, Warren, M.J, Getzoff, E.D. | Deposit date: | 2003-06-03 | Release date: | 2003-12-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis. Nat.Struct.Biol., 10, 2003
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1OHL
| YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE PUTATIVE CYCLIC REACTION INTERMEDIATE COMPLEX | Descriptor: | 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, BETA-MERCAPTOETHANOL, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ... | Authors: | Erskine, P.T, Coates, L, Butler, D, Youell, J.H, Brindley, A.A, Wood, S.P, Warren, M.J, Shoolingin-Jordan, P.M, Cooper, J.B. | Deposit date: | 2003-05-27 | Release date: | 2003-06-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-Ray Structure of a Putative Reaction Intermediateof 5-Aminolaevulinic Acid Dehydratase Biochem.J., 373, 2003
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1QNV
| yeast 5-aminolaevulinic acid dehydratase Lead (Pb) complex | Descriptor: | 5-AMINOLAEVULINIC ACID DEHYDRATASE, LEAD (II) ION | Authors: | Erskine, P.T, Senior, N.M, Warren, M.J, Wood, S.P, Cooper, J.B. | Deposit date: | 1999-10-21 | Release date: | 2000-10-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites Acta Crystallogr.,Sect.D, 56, 2000
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1QML
| Hg complex of yeast 5-aminolaevulinic acid dehydratase | Descriptor: | 5-AMINOLAEVULINIC ACID DEHYDRATASE, MERCURY (II) ION | Authors: | Erskine, P.T, Senior, N, Warren, M.J, Wood, S.P, Cooper, J.B. | Deposit date: | 1999-10-02 | Release date: | 2000-10-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | MAD Analyses of Yeast 5-Aminolaevulinic Acid Dehydratase. Their Use in Structure Determination and in Defining the Metal Binding Sites Acta Crystallogr.,Sect.D, 56, 2000
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1EB3
| YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 4,7-DIOXOSEBACIC ACID COMPLEX | Descriptor: | 4,7-DIOXOSEBACIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Coates, L, Newbold, R, Brindley, A.A, Stauffer, F, Wood, S.P, Warren, M.J, Cooper, J.B, Shoolingin-Jordan, P.M, Neier, R. | Deposit date: | 2001-07-18 | Release date: | 2001-08-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors FEBS Lett., 503, 2001
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1S4D
| Crystal Structure Analysis of the S-adenosyl-L-methionine dependent uroporphyrinogen-III C-methyltransferase SUMT | Descriptor: | GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, Uroporphyrin-III C-methyltransferase | Authors: | Vevodova, J, Graham, R.M, Raux, E, Schubert, H.L, Roper, D.I, Brindley, A.A, Scott, A.I, Roessner, C.A, Stamford, N.P.J, Stroupe, M.E, Getzoff, E.D, Warren, M.J, Wilson, K.S. | Deposit date: | 2004-01-16 | Release date: | 2004-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure/Function Studies on a S-Adenosyl-l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis J.Mol.Biol., 344, 2004
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3NJR
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5C4R
| CobK precorrin-6A reductase | Descriptor: | Precorrin-6A reductase | Authors: | Gu, S, Pickersgill, R.W. | Deposit date: | 2015-06-18 | Release date: | 2016-11-16 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Crystal structure of CobK reveals strand-swapping between Rossmann-fold domains and molecular basis of the reduced precorrin product trap. Sci Rep, 5, 2015
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3M4Z
| Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site | Descriptor: | CHLORIDE ION, COBALT (II) ION, Ferrochelatase, ... | Authors: | Soderberg, C.A.G, Hansson, M.D, Sreekanth, R, Al-Karadaghi, S, Hansson, M. | Deposit date: | 2010-03-12 | Release date: | 2010-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase To be Published
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2XVY
| Cobalt chelatase CbiK (periplasmic) from Desulvobrio vulgaris Hildenborough (co-crystallised with cobalt and SHC) | Descriptor: | CHELATASE, PUTATIVE, COBALT (II) ION, ... | Authors: | Romao, C.V, Lobo, S.A.L, Carrondo, M.A, Saraiva, L.M, Matias, P.M. | Deposit date: | 2010-10-28 | Release date: | 2011-11-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Desulfovibrio vulgaris CbiK(P) cobaltochelatase: evolution of a haem binding protein orchestrated by the incorporation of two histidine residues. Environ. Microbiol., 19, 2017
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2XVZ
| Cobalt chelatase CbiK (periplasmatic) from Desulvobrio vulgaris Hildenborough (co-crystallized with cobalt) | Descriptor: | CHELATASE, PUTATIVE, CHLORIDE ION, ... | Authors: | Romao, C.V, Lobo, S.A.L, Carrondo, M.A, Saraiva, L.M, Matias, P.M. | Deposit date: | 2010-10-28 | Release date: | 2010-12-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Evolution in a Family of Chelatases Facilitated by the Introduction of Active Site Asymmetry and Protein Oligomerization. Proc.Natl.Acad.Sci.USA, 108, 2011
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2XVX
| Cobalt chelatase CbiK (periplasmatic) from Desulvobrio vulgaris Hildenborough (Native) | Descriptor: | CARBON DIOXIDE, CHELATASE, PUTATIVE, ... | Authors: | Romao, C.V, Lobo, S.A.L, Carrondo, M.A, Saraiva, L.M, Matias, P.M. | Deposit date: | 2010-10-28 | Release date: | 2010-12-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evolution in a Family of Chelatases Facilitated by the Introduction of Active Site Asymmetry and Protein Oligomerization. Proc.Natl.Acad.Sci.USA, 108, 2011
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2DJ5
| Crystal Structure of the vitamin B12 biosynthetic cobaltochelatase, CbiXS, from Archaeoglobus fulgidus | Descriptor: | GLYCEROL, PHOSPHATE ION, Sirohydrochlorin cobaltochelatase | Authors: | Yin, J, Cherney, M.M, James, M.N.G. | Deposit date: | 2006-03-31 | Release date: | 2006-09-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal Structure of the Vitamin B(12) Biosynthetic Cobaltochelatase, CbiX (S), from Archaeoglobus Fulgidus J.STRUCT.FUNCT.GENOM., 7, 2006
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1AW5
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