4B9W
| Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45. | Descriptor: | GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1 | Authors: | Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S. | Deposit date: | 2012-09-08 | Release date: | 2012-10-17 | Last modified: | 2019-04-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors. Rna, 18, 2012
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6HIP
| Structure of SPF45 UHM bound to HIV-1 Rev ULM | Descriptor: | HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ... | Authors: | Pabis, M, Corsini, L, Sattler, M. | Deposit date: | 2018-08-30 | Release date: | 2019-03-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors. Nucleic Acids Res., 47, 2019
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2L8D
| Structure/function of the LBR Tudor domain | Descriptor: | Lamin-B receptor | Authors: | Liokatis, S, Edlich, C, Soupsana, K, Giannios, I, Sattler, M, Georgatos, S.D, Politou, A.S. | Deposit date: | 2011-01-10 | Release date: | 2011-11-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure and molecular interactions of lamin B receptor tudor domain. J.Biol.Chem., 287, 2012
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6YIG
| Crystal structure of the N-terminal EF-hand domain of Arabidopsis thaliana AtEH1/Pan1 | Descriptor: | CALCIUM ION, Calcium-binding EF hand family protein, SODIUM ION | Authors: | Yperman, K, Merceron, R, De Munck, S, Bloch, Y, Savvides, S.N, Pleskot, R, Van Damme, D. | Deposit date: | 2020-04-01 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding. Nat Commun, 12, 2021
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5L87
| Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases. | Descriptor: | 1,2-ETHANEDIOL, 5-(1~{H}-indol-3-ylmethyl)-1-methyl-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, Peroxin 14 | Authors: | Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M. | Deposit date: | 2016-06-07 | Release date: | 2017-03-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (0.87 Å) | Cite: | Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites. Science, 355, 2017
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5L8A
| Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases. | Descriptor: | 1,2-ETHANEDIOL, 1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(phenylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, GLYCINE, ... | Authors: | Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M. | Deposit date: | 2016-06-07 | Release date: | 2017-03-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites. Science, 355, 2017
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5N8V
| Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases. | Descriptor: | 1-(2-azanylethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M. | Deposit date: | 2017-02-24 | Release date: | 2017-03-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites. Science, 355, 2017
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7OX5
| hIL-9:hIL-9Ra complex | Descriptor: | Interleukin-9, Interleukin-9 receptor, SULFATE ION | Authors: | De Vos, T, Savvides, S.N. | Deposit date: | 2021-06-22 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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7OX3
| Fab 6D3: hIL-9 complex | Descriptor: | Heavy chain (Fab 6D3), Interleukin-9, Light chain (Fab 6D3), ... | Authors: | De Vos, T, Savvides, S.N. | Deposit date: | 2021-06-22 | Release date: | 2022-12-28 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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7OX2
| Fab 6E2: hIL-9 complex | Descriptor: | Heavy chain (Fab 6E2), Interleukin-9, Light chain (Fab 6E2), ... | Authors: | De Vos, T, Savvides, S.N. | Deposit date: | 2021-06-22 | Release date: | 2022-12-28 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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7OX1
| Fab 7D6: hIL-9 complex | Descriptor: | Heavy chain (Fab 7D6), Interleukin-9, Light chain (Fab 7D6) | Authors: | De Vos, T, Savvides, S.N. | Deposit date: | 2021-06-22 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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7OX4
| Mouse interleukin-9 in complex with Fab 35D8. | Descriptor: | ACETATE ION, Heavy chain (Fab 35D8), Interleukin-9, ... | Authors: | De Vos, T, Savvides, S.N. | Deposit date: | 2021-06-22 | Release date: | 2022-12-28 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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7SKN
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7SKP
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7SKO
| De novo synthetic protein DIG8-CC (orthogonal space group) | Descriptor: | De novo synthetic protein DIG8-CC, MAGNESIUM ION | Authors: | Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. | Deposit date: | 2021-10-21 | Release date: | 2022-10-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | De novo design of immunoglobulin-like domains Nat Commun, 13, 2022
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