2V4X
 
 | | Crystal Structure of Jaagsiekte Sheep Retrovirus Capsid N-terminal domain | | Descriptor: | CAPSID PROTEIN P27 | | Authors: | Mortuza, G.B, Goldstone, D.C, Pashley, C, Haire, L.F, Palmarini, M, Taylor, W.R, Stoye, J.P, Taylor, I.A. | | Deposit date: | 2008-09-30 | | Release date: | 2008-11-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus.
J.Mol.Biol., 386, 2009
|
|
6XU1
 | | Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | | Deposit date: | 2020-01-17 | | Release date: | 2020-06-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
|
|
6YOM
 | | Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dATP, dCMPNPP, Mn and Mg | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | | Deposit date: | 2020-04-14 | | Release date: | 2020-06-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
|
|
2X1B
 | | Structure of RNA15 RRM | | Descriptor: | MRNA 3'-END-PROCESSING PROTEIN RNA15, PHOSPHATE ION | | Authors: | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | | Deposit date: | 2010-01-06 | | Release date: | 2010-02-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
|
|
3U1N
 | | Structure of the catalytic core of human SAMHD1 | | Descriptor: | PHOSPHATE ION, SAM domain and HD domain-containing protein 1, ZINC ION | | Authors: | Goldstone, D.C, Ennis-Adeniran, V, Walker, P.A, Haire, L.F, Webb, M, Taylor, I.A. | | Deposit date: | 2011-09-30 | | Release date: | 2011-11-16 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
Nature, 480, 2011
|
|
2X1A
 | | Structure of Rna15 RRM with RNA bound (G) | | Descriptor: | 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15 | | Authors: | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | | Deposit date: | 2010-01-06 | | Release date: | 2010-02-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
|
|
2X1F
 | | Structure of Rna15 RRM with bound RNA (GU) | | Descriptor: | 5'-R(*GP*UP*UP*GP*UP)-3', MRNA 3'-END-PROCESSING PROTEIN RNA15 | | Authors: | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | | Deposit date: | 2010-01-06 | | Release date: | 2010-02-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
|
|
2Y4Z
 | | Structure of the amino-terminal capsid restriction escape mutation N- MLV L10W | | Descriptor: | CAPSID PROTEIN P30, GLYCEROL | | Authors: | Goldstone, D.C, Holden-Dye, K, Ohkura, S, Stoye, J.P, Taylor, I.A. | | Deposit date: | 2011-01-11 | | Release date: | 2011-11-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Novel Escape Mutants Suggest an Extensive Trim5Alpha Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein.
Plos Pathog., 7, 2011
|
|
1G6G
 | |
2NPI
 | | Clp1-ATP-Pcf11 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein CLP1, ... | | Authors: | Noble, C.G, Beuth, B, Taylor, I.A. | | Deposit date: | 2006-10-27 | | Release date: | 2006-12-19 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
Nucleic Acids Res., 35, 2007
|
|
8COO
 | | Solution structure of Zipcode binding protein 1 (ZBP1) KH3(DD)KH4 domains in complex with N6-Methyladenosine containing RNA | | Descriptor: | Insulin-like growth factor 2 mRNA-binding protein 1, RNA_(5'-R(*(UP*CP*GP*GP*(6MZ)P*CP*U)-3') | | Authors: | Nicastro, G, Abis, G, Taylor, I.A, Ramos, A. | | Deposit date: | 2023-02-28 | | Release date: | 2024-02-07 | | Method: | SOLUTION NMR | | Cite: | Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers.
Nucleic Acids Res., 51, 2023
|
|
1U7K
 | | Structure of a hexameric N-terminal domain from murine leukemia virus capsid | | Descriptor: | Gag polyprotein | | Authors: | Mortuza, G.B, Haire, L.F, Stevens, A, Smerdon, S.J, Stoye, J.P, Taylor, I.A. | | Deposit date: | 2004-08-04 | | Release date: | 2004-10-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | High-resolution structure of a retroviral capsid hexameric amino-terminal domain.
Nature, 431, 2004
|
|
2ASB
 | | Structure of a Mycobacterium tuberculosis NusA-RNA complex | | Descriptor: | Transcription elongation protein nusA, ribosomal RNA (5'- GAACUCAAUAG -3') | | Authors: | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | | Deposit date: | 2005-08-23 | | Release date: | 2005-10-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
|
|
2ATW
 | | Structure of a Mycobacterium tuberculosis NusA-RNA complex | | Descriptor: | Transcription elongation protein nusA, ribosomal RNA (5'- AGAACUCAAUAG -3') | | Authors: | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | | Deposit date: | 2005-08-26 | | Release date: | 2005-10-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
|
|
2BF0
 | | crystal structure of the rpr of pcf11 | | Descriptor: | CALCIUM ION, PCF11 | | Authors: | Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A. | | Deposit date: | 2004-12-02 | | Release date: | 2005-01-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd.
Nat.Struct.Mol.Biol., 12, 2005
|
|
5AJA
 | | Crystal structure of mandrill SAMHD1 (amino acid residues 1-114) bound to Vpx isolated from mandrill and human DCAF1 (amino acid residues 1058-1396) | | Descriptor: | PROTEIN VPRBP, SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN, VPX PROTEIN, ... | | Authors: | Schwefel, D, Boucherit, V.C, Christodoulou, E, Walker, P.A, Stoye, J.P, Bishop, K.N, Taylor, I.A. | | Deposit date: | 2015-02-20 | | Release date: | 2015-04-22 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.649 Å) | | Cite: | Molecular Determinants for Recognition of Divergent Samhd1 Proteins by the Lentiviral Accessory Protein Vpx.
Cell Host Microbe., 17, 2015
|
|
5AO1
 | |
5AO0
 | |
5AO2
 | |
5AO3
 | |
5AO4
 | |
3BP9
 | | Structure of B-tropic MLV capsid N-terminal domain | | Descriptor: | GLYCEROL, Gag protein, ISOPROPYL ALCOHOL | | Authors: | Gulnahar, M.B, Dodding, M.P, Goldstone, D.C, Haire, L.F, Stoye, J.P, Taylor, I.A. | | Deposit date: | 2007-12-18 | | Release date: | 2008-02-12 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation
J.Mol.Biol., 376, 2008
|
|
4CC9
 | | Crystal structure of human SAMHD1 (amino acid residues 582-626) bound to Vpx isolated from sooty mangabey and human DCAF1 (amino acid residues 1058-1396) | | Descriptor: | DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, PROTEIN VPRBP, PROTEIN VPX, ... | | Authors: | Schwefel, D, Groom, H.C.T, Boucherit, V.C, Christodoulou, E, Walker, P.A, Stoye, J.P, Bishop, K.N, Taylor, I.A. | | Deposit date: | 2013-10-19 | | Release date: | 2013-12-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.473 Å) | | Cite: | Structural Basis of Lentiviral Subversion of a Cellular Protein Degradation Pathway.
Nature, 505, 2014
|
|
6ES4
 | | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets | | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ... | | Authors: | Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A. | | Deposit date: | 2017-10-19 | | Release date: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.
Nat Commun, 9, 2018
|
|
6S7X
 | | dARC1 capsid domain dimer, orthorhombic form at 1.7 Angstrom | | Descriptor: | Activity-regulated cytoskeleton associated protein 1, CHLORIDE ION, SODIUM ION | | Authors: | Cottee, M.A, Taylor, I.A. | | Deposit date: | 2019-07-07 | | Release date: | 2020-01-15 | | Last modified: | 2020-01-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure ofDrosophila melanogasterARC1 reveals a repurposed molecule with characteristics of retroviral Gag.
Sci Adv, 6, 2020
|
|
