1ESF
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![BU of 1esf by Molmil](/molmil-images/mine/1esf) | STAPHYLOCOCCAL ENTEROTOXIN A | Descriptor: | CADMIUM ION, STAPHYLOCOCCAL ENTEROTOXIN A | Authors: | Schad, E.M, Svensson, L.A. | Deposit date: | 1995-05-25 | Release date: | 1996-07-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the superantigen staphylococcal enterotoxin type A. EMBO J., 14, 1995
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2IEA
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![BU of 2iea by Molmil](/molmil-images/mine/2iea) | E. coli pyruvate dehydrogenase | Descriptor: | MAGNESIUM ION, Pyruvate dehydrogenase E1 component, THIAMINE DIPHOSPHATE | Authors: | Furey, W, Arjunan, P. | Deposit date: | 2006-09-18 | Release date: | 2006-10-03 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution. Biochemistry, 41, 2002
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2G28
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![BU of 2g28 by Molmil](/molmil-images/mine/2g28) | E. Coli Pyruvate Dehydrogenase H407A variant Phosphonolactylthiamin Diphosphate Complex | Descriptor: | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, Pyruvate dehydrogenase E1 component | Authors: | Furey, W, Arjunan, P, Chandrasekhar, K. | Deposit date: | 2006-02-15 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct. J.Biol.Chem., 281, 2006
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2G25
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![BU of 2g25 by Molmil](/molmil-images/mine/2g25) | E. Coli Pyruvate Dehydrogenase Phosphonolactylthiamin Diphosphate Complex | Descriptor: | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Furey, W, Arjunan, P, Chandrasekhar, K. | Deposit date: | 2006-02-15 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct. J.Biol.Chem., 281, 2006
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2G67
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1FV3
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![BU of 1fv3 by Molmil](/molmil-images/mine/1fv3) | THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH AN ANALOGUE OF ITS GANGLIOSIDE RECEPTOR GT1B | Descriptor: | ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ... | Authors: | Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W. | Deposit date: | 2000-09-18 | Release date: | 2001-09-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. J.Biol.Chem., 276, 2001
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1FV2
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![BU of 1fv2 by Molmil](/molmil-images/mine/1fv2) | The Hc fragment of tetanus toxin complexed with an analogue of its ganglioside receptor GT1B | Descriptor: | ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ... | Authors: | Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W. | Deposit date: | 2000-09-18 | Release date: | 2001-09-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. J.Biol.Chem., 276, 2001
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1L8A
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![BU of 1l8a by Molmil](/molmil-images/mine/1l8a) | E. COLI PYRUVATE DEHYDROGENASE | Descriptor: | MAGNESIUM ION, Pyruvate dehydrogenase E1 component, THIAMINE DIPHOSPHATE | Authors: | Furey, W, Arjunan, P. | Deposit date: | 2002-03-19 | Release date: | 2002-07-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution. Biochemistry, 41, 2002
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1D0H
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![BU of 1d0h by Molmil](/molmil-images/mine/1d0h) | THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH N-ACETYL-GALACTOSAMINE | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, PROTEIN (TETANUS TOXIN HC), SULFATE ION | Authors: | Emsley, P, Fotinou, C, Black, I, Fairweather, N.F, Charles, I.G, Watts, C, Hewitt, E, Isaacs, N.W. | Deposit date: | 1999-09-10 | Release date: | 2000-03-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem., 275, 2000
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1DIW
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![BU of 1diw by Molmil](/molmil-images/mine/1diw) | THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH GALACTOSE | Descriptor: | TETANUS TOXIN HC, beta-D-galactopyranose | Authors: | Emsley, P, Fotinou, C, Black, I, Fairweather, N.F, Charles, I.G, Watts, C, Hewitt, E, Isaacs, N.W. | Deposit date: | 1999-11-30 | Release date: | 2000-03-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem., 275, 2000
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1DLL
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![BU of 1dll by Molmil](/molmil-images/mine/1dll) | The HC fragement of tetanus toxin complexed with lactose | Descriptor: | GLYCEROL, TETANUS TOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Emsley, P, Fotinou, C, Black, I, Fairweather, N.F, Charles, I.G, Watts, C, Hewitt, E, Isaacs, N.W. | Deposit date: | 1999-12-10 | Release date: | 2000-03-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem., 275, 2000
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1DFQ
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![BU of 1dfq by Molmil](/molmil-images/mine/1dfq) | THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH SIALIC ACID | Descriptor: | N-acetyl-beta-neuraminic acid, TETANUS TOXIN HC | Authors: | Emsley, P, Fotinou, C, Black, I, Fairweather, N.F, Charles, I.G, Watts, C, Hewitt, E, Isaacs, N.W. | Deposit date: | 1999-11-20 | Release date: | 2000-03-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem., 275, 2000
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5L7H
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![BU of 5l7h by Molmil](/molmil-images/mine/5l7h) | MCR IN COMPLEX WITH ligand | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 3-methyl-5,8-dioxa-17lambda-thia-4,18-diazatetracyclo[18.2.2.1,.0]pentacosa-1(22),2(6),3,9,11,13(25),20,23-octaene-17,17-dione, Mineralocorticoid receptor, ... | Authors: | Xue, Y, Aagaard, A, Backstrom, S, Edman, K. | Deposit date: | 2016-06-03 | Release date: | 2016-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity. ChemMedChem, 12, 2017
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5L7E
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![BU of 5l7e by Molmil](/molmil-images/mine/5l7e) | MCR IN COMPLEX WITH ligand | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... | Authors: | Edman, K, Aagaard, A, Backstrom, S, Xue, Y. | Deposit date: | 2016-06-03 | Release date: | 2016-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity. ChemMedChem, 12, 2017
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5L7G
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![BU of 5l7g by Molmil](/molmil-images/mine/5l7g) | MCR IN COMPLEX WITH ligand | Descriptor: | 1,2-ETHANEDIOL, Mineralocorticoid receptor, NCOA1 peptide, ... | Authors: | Edman, K, Aagaard, A, Backstrom, S, Xue, Y. | Deposit date: | 2016-06-03 | Release date: | 2016-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity. ChemMedChem, 12, 2017
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5VBJ
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![BU of 5vbj by Molmil](/molmil-images/mine/5vbj) | |