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7AL3
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BU of 7al3 by Molmil
Native-like genome-containing particle of DWV in acidic pH
Descriptor: Genome polyprotein
Authors:Skubnik, K, Plevka, P.
Deposit date:2020-10-04
Release date:2021-02-10
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Capsid opening enables genome release of iflaviruses.
Sci Adv, 7, 2021
7ZPK
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BU of 7zpk by Molmil
Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate and TARBP2 subunit
Descriptor: 59-nt precursor of miR-15a, Endoribonuclease Dicer, RISC-loading complex subunit TARBP2
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-04-27
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7ZPI
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BU of 7zpi by Molmil
Mammalian Dicer in the "dicing state" with pre-miR-15a substrate
Descriptor: 59-nt precursor of miR-15a, Endoribonuclease Dicer
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-04-27
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (5.91 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
7ZPJ
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BU of 7zpj by Molmil
Mammalian Dicer in the "pre-dicing state" with pre-miR-15a substrate and TARBP2 subunit
Descriptor: 59-nt precursor of miR-15a, Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 isoform 1
Authors:Zanova, M, Zapletal, D, Kubicek, K, Stefl, R, Pinkas, M, Novacek, J.
Deposit date:2022-04-27
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Mol.Cell, 82, 2022
6APT
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BU of 6apt by Molmil
Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)
Descriptor: DI(HYDROXYETHYL)ETHER, Hypoxanthine-guanine phosphoribosyltransferase, {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)
Authors:Teran, D, Guddat, L.W.
Deposit date:2017-08-17
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
6AR9
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BU of 6ar9 by Molmil
Crystal structure of hypoxanthine-guanine-xanthine phosphorybosyltranferase in complex with [(2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl][(E)-2-phosphonoethenyl]amino}ethoxy)methyl]phosphonic acid
Descriptor: Hypoxanthine-guanine phosphoribosyltransferase, putative, MAGNESIUM ION, ...
Authors:Teran, D, Gudday, L.W.
Deposit date:2017-08-21
Release date:2018-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
6APS
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BU of 6aps by Molmil
Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with [(2-((Guanine-9H-yl)methyl)propane-1,3 diyl)bis(oxy)]bis(methylene))diphosphonic acid
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Hypoxanthine-guanine phosphoribosyltransferase, ...
Authors:Teran, D, Guddat, L.W.
Deposit date:2017-08-17
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
6APV
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BU of 6apv by Molmil
Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with [(2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl][(E)-2-phosphonoethenyl]amino}ethoxy)methyl]phosphonic acid
Descriptor: DI(HYDROXYETHYL)ETHER, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, ...
Authors:Teran, D, Guddat, L.W.
Deposit date:2017-08-18
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.993 Å)
Cite:Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
6APU
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BU of 6apu by Molmil
Crystal structure of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltranferase in complex with (2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](3-aminopropyl)amino}ethyl)phosphonic acid
Descriptor: (2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](3-aminopropyl)amino}ethyl)phosphonic acid, DI(HYDROXYETHYL)ETHER, Hypoxanthine-guanine phosphoribosyltransferase, ...
Authors:Teran, D, Guddat, L.
Deposit date:2017-08-18
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.842 Å)
Cite:Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
6AQO
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BU of 6aqo by Molmil
Crystal structure of hypoxanthine-guanine-xanthine phosphorybosyltranferase in complex with {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)
Descriptor: Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)
Authors:Teran, D, Gudday, L.W.
Deposit date:2017-08-21
Release date:2018-03-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
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