8DH6
| Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid nanodiscs | Descriptor: | CALCIUM ION, COPPER (II) ION, Cytochrome c oxidase subunit 1, ... | Authors: | Godoy, A.S, Song, Y, Cheruvara, H, Quigley, A, Oliva, G. | Deposit date: | 2022-06-25 | Release date: | 2022-07-20 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid nanodiscs To Be Published
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8DH7
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1QXS
| CRYSTAL STRUCTURE OF Trypanosoma cruzi GLYCERALDEHYDE-3- PHOSPHATE DEHYDROGENASE COMPLEXED WITH AN ANALOGUE OF 1,3- BisPHOSPHO-D-GLYCERIC ACID | Descriptor: | 3-HYDROXY-2-OXO-4-PHOPHONOXY- BUTYL)-PHOSPHONIC ACID, Glyceraldehyde 3-phosphate dehydrogenase, glycosomal, ... | Authors: | Castilho, M.S, Pavao, F, Oliva, G. | Deposit date: | 2003-09-08 | Release date: | 2004-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-d-glyceric acid. Eur.J.Biochem., 270, 2003
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8EYJ
| Crystal Structure of uncleaved SARS-CoV-2 Main Protease C145S mutant in complex with Nirmatrelvir | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Noske, G.D, Godoy, A.S, Oliva, G. | Deposit date: | 2022-10-27 | Release date: | 2022-11-16 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.738 Å) | Cite: | An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition. Nat Commun, 14, 2023
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1RP0
| Crystal Structure of Thi1 protein from Arabidopsis thaliana | Descriptor: | ADENOSINE DIPHOSPHATE 5-(BETA-ETHYL)-4-METHYL-THIAZOLE-2-CARBOXYLIC ACID, HEPTANE-1,2,3-TRIOL, Thiazole biosynthetic enzyme, ... | Authors: | Godoi, P.H.C, Van Sluys, M.A, Menck, C.F.M, Oliva, G. | Deposit date: | 2003-12-02 | Release date: | 2005-02-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the thiazole biosynthetic enzyme THI1 from Arabidopsis thaliana. J.Biol.Chem., 281, 2006
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7RB2
| Cryo-EM structure of SARS-CoV-2 NSP15 NendoU in BIS-Tris pH 6.0 | Descriptor: | Uridylate-specific endoribonuclease | Authors: | Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G. | Deposit date: | 2021-07-05 | Release date: | 2021-07-14 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 51, 2023
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7RB0
| Cryo-EM structure of SARS-CoV-2 NSP15 NendoU at pH 7.5 | Descriptor: | Uridylate-specific endoribonuclease | Authors: | Godoy, A.S, Song, Y, Nakamura, A.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliva, G. | Deposit date: | 2021-07-05 | Release date: | 2021-07-14 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 51, 2023
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7S82
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3E9R
| Crystal structure of purine nucleoside phosphorylase from Schistosoma mansoni in complex with adenine | Descriptor: | ACETATE ION, ADENINE, DIMETHYL SULFOXIDE, ... | Authors: | Pereira, H.M, Rezende, M.M, Oliva, G, Garratt, R.C. | Deposit date: | 2008-08-23 | Release date: | 2009-09-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni. Acta Crystallogr.,Sect.D, 66, 2010
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3FB1
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3FNQ
| Crystal structure of schistosoma purine nucleoside phosphorylase in complex with hypoxanthine | Descriptor: | DIMETHYL SULFOXIDE, HYPOXANTHINE, Purine-nucleoside phosphorylase, ... | Authors: | Castilho, M.S, Pereira, H.M, Garratt, R.C, Oliva, G. | Deposit date: | 2008-12-26 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni. Acta Crystallogr.,Sect.D, 66, 2010
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3FAZ
| Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with inosine | Descriptor: | INOSINE, Purine-nucleoside phosphorylase, SULFATE ION | Authors: | Pereira, H.M, Garratt, R.C, Oliva, G. | Deposit date: | 2008-11-18 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni. Acta Crystallogr.,Sect.D, 66, 2010
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3DJF
| Crystal Structure of Schistosoma mansoni Purine Nucleoside Phosphorylase in a complex with BCX-34 | Descriptor: | 2-amino-7-(pyridin-3-ylmethyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase, ... | Authors: | Postigo, M.P, Pereira, H.M, Oliva, G, Andricopulo, A.D. | Deposit date: | 2008-06-23 | Release date: | 2009-06-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies. Bioorg.Med.Chem., 18, 2010
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3DSL
| The Three-dimensional Structure of Bothropasin, the Main Hemorrhagic Factor from Bothrops jararaca venom. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FUROYL-LEUCINE, ... | Authors: | Muniz, J.R.C, Ambrosio, A, Selistre-de-Araujo, H.S, Oliva, G, Garratt, R.C, Souza, D.H.F. | Deposit date: | 2008-07-13 | Release date: | 2008-10-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The three-dimensional structure of bothropasin, the main hemorrhagic factor from Bothrops jararaca venom: Insights for a new classification of snake venom metalloprotease subgroups. Toxicon, 52, 2008
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3F8W
| Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with adenosine | Descriptor: | ADENOSINE, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase, ... | Authors: | Pereira, H.M, Rezende, M.M, Garratt, R.C, Oliva, G. | Deposit date: | 2008-11-13 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni. Acta Crystallogr.,Sect.D, 66, 2010
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3FP5
| Crystal structure of ACBP from Moniliophthora perniciosa | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acyl-CoA Binding Protein, ZINC ION | Authors: | Monzani, P.S, Pereira, H.M, Melo, F.A, Meirelles, F.V, Oliva, G, Cascardo, J.C.M. | Deposit date: | 2009-01-04 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | A new topology of ACBP from Moniliophthora perniciosa. Biochim.Biophys.Acta, 1804, 2010
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3E9Z
| Crystal structure of purine nucleoside phosphorylase from Schistosoma mansoni in complex with 6-chloroguanine | Descriptor: | 6-chloroguanine, ACETATE ION, DIMETHYL SULFOXIDE, ... | Authors: | Pereira, H.M, Rezende, M.M, Oliva, G, Garratt, R.C. | Deposit date: | 2008-08-24 | Release date: | 2009-09-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase (SmPNP) in complex with adenine, 8-aminoguanine, 8-azaguanine and 6-chloroguanine. To be Published
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1ML3
| Evidences for a flip-flop catalytic mechanism of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, from its crystal structure in complex with reacted irreversible inhibitor 2-(2-phosphono-ethyl)-acrylic acid 4-nitro-phenyl ester | Descriptor: | (3-FORMYL-BUT-3-ENYL)-PHOSPHONIC ACID, Glyceraldehyde 3-phosphate dehydrogenase, glycosomal, ... | Authors: | Castilho, M.S, Pavao, F, Oliva, G. | Deposit date: | 2002-08-29 | Release date: | 2003-07-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Evidence for the Two Phosphate Binding Sites of an Analogue of the Thioacyl Intermediate for the Trypanosoma cruzi Glyceraldehyde-3-phosphate Dehydrogenase-Catalyzed Reaction, from Its Crystal Structure. Biochemistry, 42, 2003
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5U04
| Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase | Descriptor: | PHOSPHATE ION, ZINC ION, Zika Virus NS5 RdRp | Authors: | Godoy, A.S, Lima, G.M.A, Oliveira, K.I.Z, Torres, N.U, Maluf, F.V, Guido, R.V.C, Oliva, G. | Deposit date: | 2016-11-22 | Release date: | 2017-02-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase. Nat Commun, 8, 2017
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1MVQ
| Cratylia mollis lectin (isoform 1) in complex with methyl-alpha-D-mannose | Descriptor: | CALCIUM ION, MANGANESE (II) ION, lectin, ... | Authors: | de Souza, G.A, Oliveira, P.S, Trapani, S, Correia, M.T, Oliva, G, Coelho, L.C, Greene, L.J. | Deposit date: | 2002-09-26 | Release date: | 2003-10-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Amino acid sequence and tertiary structure of Cratylia mollis seed lectin Glycobiology, 13, 2003
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1MZV
| Crystal Structure of Adenine Phosphoribosyltransferase (APRT) From Leishmania tarentolae | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenine Phosphoribosyltransferase, PHOSPHATE ION | Authors: | Thiemann, O.H, Silva, M, Oliva, G, Silva, C.H.T.P, Iulek, J. | Deposit date: | 2002-10-10 | Release date: | 2003-10-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of adenine phosphoribosyltransferase from Leishmania tarentolae: potential implications for APRT catalytic mechanism. Biochim.Biophys.Acta, 1696, 2004
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7KEG
| Crystal structure from SARS-COV2 NendoU NSP15 | Descriptor: | PHOSPHATE ION, Uridylate-specific endoribonuclease | Authors: | Godoy, A.S, Nakamura, A.M, Pereira, H.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliveira, K.I.Z, Oliva, G. | Deposit date: | 2020-10-10 | Release date: | 2020-12-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 2023
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7KFI
| SARS-CoV-2 Main protease immature form - apo structure | Descriptor: | 3C-like proteinase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE | Authors: | Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Oliva, G, Godoy, A.S. | Deposit date: | 2020-10-14 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process. J.Mol.Biol., 433, 2021
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7KVR
| SARS-CoV-2 Main protease immature form - FMAX Library E09 fragment | Descriptor: | 3C-like proteinase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | Authors: | Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Fernandes, R.S, Oliva, G, Godoy, A.S. | Deposit date: | 2020-11-28 | Release date: | 2020-12-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process. J.Mol.Biol., 433, 2021
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7KF4
| Crystal structure from SARS-CoV-2 NendoU NSP15 | Descriptor: | CITRIC ACID, Uridylate-specific endoribonuclease | Authors: | Godoy, A.S, Nakamura, A.M, Pereira, H.M, Noske, G.D, Gawriljuk, V.O, Fernandes, R.S, Oliveira, K.I.Z, Oliva, G. | Deposit date: | 2020-10-13 | Release date: | 2020-12-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res., 2023
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