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4QEO
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BU of 4qeo by Molmil
crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH
Descriptor: DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ...
Authors:Du, J, Li, S, Patel, D.J.
Deposit date:2014-05-17
Release date:2014-07-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
3Q0C
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BU of 3q0c by Molmil
Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122
Descriptor: DNA (5'-D(*AP*CP*TP*AP*(5CM)P*GP*TP*AP*GP*TP*T)-3'), Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, ...
Authors:Eerappa, R, Simanshu, D.K, Patel, D.J.
Deposit date:2010-12-15
Release date:2011-02-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6567 Å)
Cite:A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
4RIK
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BU of 4rik by Molmil
Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77
Descriptor: Alpha-synuclein
Authors:Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S.
Deposit date:2014-10-06
Release date:2015-08-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
4RP7
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BU of 4rp7 by Molmil
Structure of the amyloid-forming segment TIITLE from p53 (residues 253-258)
Descriptor: TIITLE hexapeptide segment from p53, ZINC ION
Authors:Soriaga, A.B, Soragni, A, Eisenberg, D.
Deposit date:2014-10-29
Release date:2016-01-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4RP6
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BU of 4rp6 by Molmil
Structure of the amyloid-forming segment LTIITLE from p53 (residues 252-258)
Descriptor: LTIITLE heptapeptide segment from p53
Authors:Soriaga, A.B, Soragni, A, Eisenberg, D.
Deposit date:2014-10-29
Release date:2016-01-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4TNE
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BU of 4tne by Molmil
Crystal Structure of Human Transthyretin Thr119Tyr Mutant
Descriptor: GLYCEROL, Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-06-03
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLS
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BU of 4tls by Molmil
Crystal Structure of Human Transthyretin Glu92Pro Mutant
Descriptor: GLYCEROL, PHOSPHATE ION, SODIUM ION, ...
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL5
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BU of 4tl5 by Molmil
Crystal Structure of Human Transthyretin Ser85Pro Mutant
Descriptor: CHLORIDE ION, SODIUM ION, Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLT
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BU of 4tlt by Molmil
Crystal structure of human transthyretin
Descriptor: MAGNESIUM ION, Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TKW
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BU of 4tkw by Molmil
Crystal Structure of Human Transthyretin Leu55Pro Mutant
Descriptor: Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-27
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL4
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BU of 4tl4 by Molmil
Crystal Structure of Human Transthyretin Val30Met Mutant
Descriptor: Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLK
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BU of 4tlk by Molmil
Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SODIUM ION, ...
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TM9
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BU of 4tm9 by Molmil
Crystal Structure of Human Transthyretin Thr119Trp Mutant
Descriptor: Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-31
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
3F4Z
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BU of 3f4z by Molmil
Trimeric helix bundle formed by an alpha/beta-peptide derivative of the HIV gp41 CHR domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, alpha/beta-peptide analogue of the HIV gp41 CHR domain
Authors:Horne, W.S, Gellman, S.H.
Deposit date:2008-11-03
Release date:2009-09-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
3F50
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BU of 3f50 by Molmil
HIV gp41 six-helix bundle composed of an alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide
Descriptor: Envelope glycoprotein gp160, GLYCEROL, alpha/beta-peptide analogue of the HIV gp41 CHR domain
Authors:Horne, W.S, Gellman, S.H.
Deposit date:2008-11-03
Release date:2009-09-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
3F4Y
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BU of 3f4y by Molmil
HIV gp41 six-helix bundle containing a mutant CHR alpha-peptide sequence
Descriptor: Envelope glycoprotein gp160, Mutant peptide derived from HIV gp41 CHR domain
Authors:Horne, W.S, Gellman, S.H.
Deposit date:2008-11-03
Release date:2009-09-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
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