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8CYR
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BU of 8cyr by Molmil
Alpha-synuclein fibril from spontaneous control
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Distinct cryo-EM structures and functions of alpha-synuclein fibrils amplified from cerebrospinal fluid
To Be Published
8D74
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BU of 8d74 by Molmil
Cryo-EM structure of human CNTF signaling complex: model containing the interaction core region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ciliary neurotrophic factor, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D7R
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BU of 8d7r by Molmil
Cryo-EM structure of human CLCF1 signaling complex: model containing the interaction core region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cardiotrophin-like cytokine factor 1, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D7E
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BU of 8d7e by Molmil
Cryo-EM structure of human CNTFR alpha in complex with the Fab fragments of two antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ciliary neurotrophic factor receptor subunit alpha, H4H25311P2 antibody Fab fragment heavy chain, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D6A
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BU of 8d6a by Molmil
Cryo-EM structure of human LIF signaling complex: model containing the interaction core region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6 receptor subunit beta, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-06
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D7H
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BU of 8d7h by Molmil
Cryo-EM structure of human CLCF1 in complex with CRLF1 and CNTFR alpha
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cardiotrophin-like cytokine factor 1, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D82
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BU of 8d82 by Molmil
Cryo-EM structure of human IL-6 signaling complex in detergent: model containing full extracellular domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D85
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BU of 8d85 by Molmil
Cryo-EM structure of human IL-27 signaling complex: model containing the interaction core region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ...
Authors:Zhou, Y, Franklin, M.C.
Deposit date:2022-06-07
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
5VKV
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BU of 5vkv by Molmil
Solution NMR structure of the membrane electron transporter CcdA
Descriptor: Cytochrome c-type biogenesis protein CcdA
Authors:Zhou, Y, Bushweller, J.H.
Deposit date:2017-04-24
Release date:2018-01-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure and elevator mechanism of the membrane electron transporter CcdA.
Nat. Struct. Mol. Biol., 25, 2018
8GUL
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BU of 8gul by Molmil
Chitin-active AA10 LPMO (GbpA) complexed with Cu(II) from Vibrio campbellii
Descriptor: COPPER (II) ION, GlcNAc-binding protein A, SULFATE ION
Authors:Zhou, Y, Robinson, R.C, Suginta, W.
Deposit date:2022-09-12
Release date:2023-06-21
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural and binding studies of a new chitin-active AA10 lytic polysaccharide monooxygenase from the marine bacterium Vibrio campbellii.
Acta Crystallogr D Struct Biol, 79, 2023
8GUM
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BU of 8gum by Molmil
Chitin-active AA10 LPMO (GbpA) from Vibrio campbellii
Descriptor: GlcNAc-binding protein A
Authors:Zhou, Y, Robinson, R.C, Suginta, W.
Deposit date:2022-09-12
Release date:2023-06-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and binding studies of a new chitin-active AA10 lytic polysaccharide monooxygenase from the marine bacterium Vibrio campbellii.
Acta Crystallogr D Struct Biol, 79, 2023
5XOH
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BU of 5xoh by Molmil
Crystal structure of bergaptol o-methyltransferase complex
Descriptor: 4-oxidanylfuro[3,2-g]chromen-7-one, Bergaptol O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Zhou, Y, Zeng, Z.
Deposit date:2017-05-28
Release date:2018-05-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of bergaptol o-methyltransferase complex
To Be Published
2K73
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BU of 2k73 by Molmil
Solution NMR structure of integral membrane protein DsbB
Descriptor: Disulfide bond formation protein B
Authors:Zhou, Y, Cierpicki, T, Flores Jimenez, R.H, Lukasik, S.M, Ellena, J.F, Cafiso, D.S, Kadokura, H, Beckwith, J, Bushweller, J.H.
Deposit date:2008-08-01
Release date:2008-10-07
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.
Mol.Cell, 31, 2008
2K74
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BU of 2k74 by Molmil
Solution NMR structure of DsbB-ubiquinone complex
Descriptor: Disulfide bond formation protein B, UBIQUINONE-2
Authors:Zhou, Y, Cierpicki, T, Flores Jimenez, R.H, Lukasik, S.M, Ellena, J.F, Cafiso, D.S, Kadokura, H, Beckwith, J, Bushweller, J.H.
Deposit date:2008-08-01
Release date:2008-10-07
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.
Mol.Cell, 31, 2008
1K4D
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BU of 1k4d by Molmil
Potassium Channel KcsA-Fab complex in low concentration of K+
Descriptor: DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
Authors:Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R.
Deposit date:2001-10-07
Release date:2001-11-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution.
Nature, 414, 2001
4F56
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BU of 4f56 by Molmil
The bicyclic intermediate structure provides insights into the desuccinylation mechanism of SIRT5
Descriptor: 3-[(2R,3aR,5R,6R,6aR)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-2,6-dihydroxytetrahydrofuro[2,3-d][1,3]oxathiol-2-yl]propanoic acid, NAD-dependent lysine demalonylase and desuccinylase sirtuin-5, mitochondrial, ...
Authors:Zhou, Y, Hao, Q.
Deposit date:2012-05-11
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5)
J.Biol.Chem., 287, 2012
1K4C
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BU of 1k4c by Molmil
Potassium Channel KcsA-Fab complex in high concentration of K+
Descriptor: DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
Authors:Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R.
Deposit date:2001-10-07
Release date:2001-11-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution.
Nature, 414, 2001
4F4U
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BU of 4f4u by Molmil
The bicyclic intermediate structure provides insights into the desuccinylation mechanism of SIRT5
Descriptor: NAD-dependent lysine demalonylase and desuccinylase sirtuin-5, mitochondrial, ZINC ION, ...
Authors:Zhou, Y, Hao, Q.
Deposit date:2012-05-11
Release date:2012-06-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5)
J.Biol.Chem., 287, 2012
6JKP
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BU of 6jkp by Molmil
Crystal structure of sulfoacetaldehyde reductase from Bifidobacterium kashiwanohense in complex with NAD+
Descriptor: Methanol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
Authors:Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z.
Deposit date:2019-03-01
Release date:2019-06-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.008 Å)
Cite:Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacteriumBifidobacterium kashiwanohense.
Biosci.Rep., 39, 2019
6JKO
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BU of 6jko by Molmil
Crystal structure of sulfoacetaldehyde reductase from Bifidobacterium kashiwanohense
Descriptor: Methanol dehydrogenase, ZINC ION
Authors:Zhou, Y, Xu, T, Lin, L, Zhang, Y, Yuchi, Z.
Deposit date:2019-03-01
Release date:2019-06-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacteriumBifidobacterium kashiwanohense.
Biosci.Rep., 39, 2019
1R3J
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BU of 1r3j by Molmil
potassium channel KcsA-Fab complex in high concentration of Tl+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
1R3K
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BU of 1r3k by Molmil
potassium channel KcsA-Fab complex in low concentration of Tl+
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ...
Authors:Zhou, Y, MacKinnon, R.
Deposit date:2003-10-02
Release date:2003-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
6LQK
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BU of 6lqk by Molmil
Crystal structure of honeybee RyR NTD
Descriptor: MAGNESIUM ION, ryanodine receptor
Authors:Zhou, Y, Lin, L, Yuchi, Z.
Deposit date:2020-01-13
Release date:2021-01-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Crystal structure of the N-terminal domain of ryanodine receptor from the honeybee, Apis mellifera.
Insect Biochem.Mol.Biol., 125, 2020
6KIM
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BU of 6kim by Molmil
Crystal structure of diamondback moth ryanodine receptor SPRY2 domain
Descriptor: GLYCEROL, Ryanodine receptor
Authors:Zhou, Y, Lin, L, Yuchi, Z.
Deposit date:2019-07-19
Release date:2020-07-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.057 Å)
Cite:Crystal structure of diamondback moth ryanodine receptor SPRY2 domain
To Be Published
6N8K
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BU of 6n8k by Molmil
Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit
Descriptor: 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019

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