1F4N
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![BU of 1f4n by Molmil](/molmil-images/mine/1f4n) | C2 CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ROP ALA2ILE2-6 | Authors: | Willis, M.A, Bishop, B, Regan, L, Brunger, A.T. | Deposit date: | 2000-06-08 | Release date: | 2001-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Dramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core. Structure Fold.Des., 8, 2000
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2HYZ
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8U3M
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![BU of 8u3m by Molmil](/molmil-images/mine/8u3m) | The FARFAR-MD-NMR ensemble of an HIV-1 TAR excited state | Descriptor: | The excited state of HIV-1 transactivation response element (31-MER) | Authors: | Geng, A, Ganser, L, Roy, R, Shi, H, Pratihar, S, Case, D.A, Al-Hashimi, H.M. | Deposit date: | 2023-09-07 | Release date: | 2023-10-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | An RNA excited conformational state at atomic resolution. Nat Commun, 14, 2023
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1XNF
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![BU of 1xnf by Molmil](/molmil-images/mine/1xnf) | Crystal structure of E.coli TPR-protein NlpI | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Lipoprotein nlpI | Authors: | Wilson, C.G, Kajander, T, Regan, L. | Deposit date: | 2004-10-04 | Release date: | 2004-11-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | The crystal structure of NlpI. A prokaryotic tetratricopeptide repeat protein with a globular fold. FEBS J., 272, 2005
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6CIU
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![BU of 6ciu by Molmil](/molmil-images/mine/6ciu) | Structure of a Thr-rich interface in an Azami Green tetramer | Descriptor: | Azami-Green | Authors: | Oi, C, Lim, C.S, Knecht, K.M, Xiong, Y, Regan, L. | Deposit date: | 2018-02-25 | Release date: | 2018-09-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A threonine zipper that mediates protein-protein interactions: Structure and prediction. Protein Sci., 27, 2018
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3KD7
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![BU of 3kd7 by Molmil](/molmil-images/mine/3kd7) | |
2QND
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1NA3
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![BU of 1na3 by Molmil](/molmil-images/mine/1na3) | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... | Authors: | Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L. | Deposit date: | 2002-11-26 | Release date: | 2003-06-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif Structure, 11, 2003
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1NA0
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![BU of 1na0 by Molmil](/molmil-images/mine/1na0) | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, ACETATE ION, CHLORIDE ION, ... | Authors: | Main, E, Xiong, Y, Cocco, M, D'Andrea, L, Regan, L. | Deposit date: | 2002-11-26 | Release date: | 2003-06-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Design of Stable alpha-Helical Arrays from an Idealized TPR Motif Structure, 11, 2003
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7L1W
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![BU of 7l1w by Molmil](/molmil-images/mine/7l1w) | Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Exo-B-1,4-beta-xylanase | Authors: | Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. | Deposit date: | 2020-12-15 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium. Biotechnol.Bioeng., 118, 2021
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7L1Y
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![BU of 7l1y by Molmil](/molmil-images/mine/7l1y) | Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium-xylobiose complex | Descriptor: | 1,2-ETHANEDIOL, Exo-B-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. | Deposit date: | 2020-12-15 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium. Biotechnol.Bioeng., 118, 2021
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7L1Z
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![BU of 7l1z by Molmil](/molmil-images/mine/7l1z) | Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium - NT-truncated form | Descriptor: | 1,2-ETHANEDIOL, Exo-B-1,4-beta-xylanase, SULFATE ION | Authors: | Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. | Deposit date: | 2020-12-15 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium. Biotechnol.Bioeng., 118, 2021
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3FWV
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![BU of 3fwv by Molmil](/molmil-images/mine/3fwv) | Crystal Structure of a Redesigned TPR Protein, T-MOD(VMY), in Complex with MEEVF Peptide | Descriptor: | Heat shock protein HSP 90-beta, Hsc70/Hsp90-organizing protein, NICKEL (II) ION | Authors: | Jackrel, M.E, Valverde, R, Regan, L. | Deposit date: | 2009-01-19 | Release date: | 2009-04-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Redesign of a protein-peptide interaction: characterization and applications Protein Sci., 18, 2009
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3ESK
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![BU of 3esk by Molmil](/molmil-images/mine/3esk) | |
7T63
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4R6A
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![BU of 4r6a by Molmil](/molmil-images/mine/4r6a) | Crystal structure of human TLR8 in complex with Hybrid-2 | Descriptor: | 1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... | Authors: | Tanji, H, Ohto, U, Shimizu, T. | Deposit date: | 2014-08-22 | Release date: | 2015-08-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Hybrid-2: AnImidazoquinoline Dual Toll-like receptor 7/8 Agonist that Potently Activates Cytokine Production by Human Newborn and Adult Leukocytes To be Published
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8J0L
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![BU of 8j0l by Molmil](/molmil-images/mine/8j0l) | Structure of DNA binding Domain of Human TFAP2A | Descriptor: | GLYCEROL, Transcription factor AP-2-alpha | Authors: | Liu, K, Xiao, Y.Q, Gan, L.Y, Min, J.R. | Deposit date: | 2023-04-11 | Release date: | 2023-07-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors. Nucleic Acids Res., 51, 2023
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6XKB
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![BU of 6xkb by Molmil](/molmil-images/mine/6xkb) | Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD | Descriptor: | S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION | Authors: | Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2020-06-26 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4. Febs Lett., 596, 2022
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8J0K
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![BU of 8j0k by Molmil](/molmil-images/mine/8j0k) | Crystal structure of human TFAP2A in complex with DNA | Descriptor: | DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*GP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*CP*GP*AP*GP*GP*CP*AP*G)-3'), GLYCEROL, ... | Authors: | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | Deposit date: | 2023-04-11 | Release date: | 2023-07-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors. Nucleic Acids Res., 51, 2023
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8J0Q
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![BU of 8j0q by Molmil](/molmil-images/mine/8j0q) | Structure of DNA binding domain of human TFAP2B | Descriptor: | GLYCEROL, Transcription factor AP-2-beta | Authors: | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | Deposit date: | 2023-04-11 | Release date: | 2023-07-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors. Nucleic Acids Res., 51, 2023
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8J0R
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![BU of 8j0r by Molmil](/molmil-images/mine/8j0r) | Structure of human TFAP2A in complex with DNA | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*AP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*GP*AP*GP*GP*CP*AP*G)-3'), ... | Authors: | Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. | Deposit date: | 2023-04-11 | Release date: | 2023-07-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors. Nucleic Acids Res., 51, 2023
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8WCP
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3E8K
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4ZO5
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![BU of 4zo5 by Molmil](/molmil-images/mine/4zo5) | PDE10 complexed with 4-isopropoxy-2-(2-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione | Descriptor: | 2-{2-[3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl}-4-(propan-2-yloxy)-1H-isoindole-1,3(2H)-dione, 3-(1-hydroxy-2-methylpropan-2-yl)-5-phenyl-3,5-dihydro-1H-imidazo[4,5-c][1,8]naphthyridine-2,4-dione, MAGNESIUM ION, ... | Authors: | Yan, Y. | Deposit date: | 2015-05-06 | Release date: | 2015-08-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of [(11)C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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1L6X
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![BU of 1l6x by Molmil](/molmil-images/mine/1l6x) | FC FRAGMENT OF RITUXIMAB BOUND TO A MINIMIZED VERSION OF THE B-DOMAIN FROM PROTEIN A CALLED Z34C | Descriptor: | IMMUNOGLOBULIN GAMMA-1 HEAVY CHAIN CONSTANT REGION, Minimized B-domain of Protein A Z34C, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Idusogie, E.E, Presta, L.G, Santoro-Gazzano, H, Totpal, K, Wong, P.Y, Ultsch, M, Meng, Y.G, Mullkerrin, M.G. | Deposit date: | 2002-03-14 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc. J.Immunol., 164, 2000
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