8WCP

Cryo-EM structure of human disease-associated P301L Tau amyloid fibril from mouse brain

Summary for 8WCP

Entry DOI	10.2210/pdb8wcp/pdb
EMDB information	37445
Descriptor	P301L Tau amyloid fibril from rTg4510 mice, Island B, Island A (3 entities in total)
Functional Keywords	amyloid, protein fibril
Biological source	Mus musculus More
Total number of polymer chains	9
Total formula weight	125228.76
Authors	Liu, K.E.,Zhao, W.B.,Liu, C. (deposition date: 2023-09-13, release date: 2024-06-19)
Primary citation	Zhao, W.,Liu, K.,Fan, Y.,Zhao, Q.,Tao, Y.,Zhang, M.,Gan, L.,Yu, W.,Sun, B.,Li, D.,Liu, C.,Wang, J. Cryo-EM structures reveal variant Tau amyloid fibrils between the rTg4510 mouse model and sporadic human tauopathies. Cell Discov, 10:27-27, 2024 Cited by PubMed: 38448404 DOI: 10.1038/s41421-023-00637-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.28 Å)

Structure validation