3ESK

Structure of HOP TPR2A domain in complex with the non-cognate Hsc70 peptide ligand

Summary for 3ESK

• Entry DOI: 10.2210/pdb3esk/pdb
• Related: 1ELR 1ELW
• Descriptor: Stress-induced-phosphoprotein 1, Heat shock cognate 71 kDa protein, NICKEL (II) ION, ... (4 entities in total)
• Functional Keywords: tpr2a, hsp90, hsc70, tetratricopeptide repeat, nucleus, tpr repeat, chaperone, stress response
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm (By similarity): P31948; Cytoplasm: P11142
• Total number of polymer chains: 2
• Total formula weight: 16474.09

Authors

Kajander, T.,Regan, L. (deposition date: 2008-10-06, release date: 2009-07-07, Last modification date: 2023-09-06)

• Primary citation: Kajander, T.,Sachs, J.N.,Goldman, A.,Regan, L.; Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering.; J.Biol.Chem., 284:25364-25374, 2009; PubMed: 19586912; DOI: 10.1074/jbc.M109.033894

Experimental method

X-RAY DIFFRACTION (2.05 Å)