1ELR

Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD

Summary for 1ELR

• Entry DOI: 10.2210/pdb1elr/pdb
• Related: 1ELW
• Descriptor: TPR2A-DOMAIN OF HOP, HSP90-PEPTIDE MEEVD, NICKEL (II) ION, ... (4 entities in total)
• Functional Keywords: hop, tpr-domain, peptide-complex, helical repeat, hsp90, protein binding, chaperone
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : P31948
• Total number of polymer chains: 2
• Total formula weight: 16230.96

Authors

Scheufler, C.,Brinker, A.,Hartl, F.U.,Moarefi, I. (deposition date: 2000-03-14, release date: 2000-04-26, Last modification date: 2017-10-04)

• Primary citation: Scheufler, C.,Brinker, A.,Bourenkov, G.,Pegoraro, S.,Moroder, L.,Bartunik, H.,Hartl, F.U.,Moarefi, I.; Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.; Cell(Cambridge,Mass.), 101:199-210, 2000; PubMed: 10786835; DOI: 10.1016/S0092-8674(00)80830-2

Experimental method

X-RAY DIFFRACTION (1.9 Å)