8S48
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![BU of 8s48 by Molmil](/molmil-images/mine/8s48) | CdaA-C11 complex | Descriptor: | 2-(1H-indol-3-yl)-N-[(1-methyl-1H-pyrrol-2-yl)methyl]ethanamine, Diadenylate cyclase | Authors: | Neumann, P, Ficner, R. | Deposit date: | 2024-02-21 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | CdaA-C11 complex To Be Published
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6ZM2
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7B51
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![BU of 7b51 by Molmil](/molmil-images/mine/7b51) | Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528 | Descriptor: | BETA-MERCAPTOETHANOL, Exportin-1, GTP-binding nuclear protein Ran, ... | Authors: | Shaikhqasem, A, Ficner, R. | Deposit date: | 2020-12-03 | Release date: | 2021-03-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Crystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP. Acta Crystallogr.,Sect.F, 77, 2021
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1QGV
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![BU of 1qgv by Molmil](/molmil-images/mine/1qgv) | HUMAN SPLICEOSOMAL PROTEIN U5-15KD | Descriptor: | SPLICEOSOMAL PROTEIN U5-15KD | Authors: | Reuter, K, Nottrott, S, Fabrizio, P, Luehrmann, R, Ficner, R. | Deposit date: | 1999-05-06 | Release date: | 1999-12-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein. J.Mol.Biol., 294, 1999
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5DTU
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![BU of 5dtu by Molmil](/molmil-images/mine/5dtu) | |
5EK8
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![BU of 5ek8 by Molmil](/molmil-images/mine/5ek8) | Crystal structure of a 9R-lipoxygenase from Cyanothece PCC8801 at 2.7 Angstroms | Descriptor: | FE (II) ION, Lipoxygenase, SODIUM ION | Authors: | Feussner, I, Ficner, R, Neumann, P, Newie, J, Andreou, A, Einsle, O. | Deposit date: | 2015-11-03 | Release date: | 2015-12-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a lipoxygenase from Cyanothece sp. may reveal novel features for substrate acquisition. J.Lipid Res., 57, 2016
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1WKD
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![BU of 1wkd by Molmil](/molmil-images/mine/1wkd) | TRNA-GUANINE TRANSGLYCOSYLASE | Descriptor: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | Authors: | Romier, C, Reuter, K, Suck, D, Ficner, R. | Deposit date: | 1996-08-06 | Release date: | 1997-07-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile. Biochemistry, 35, 1996
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1WKE
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![BU of 1wke by Molmil](/molmil-images/mine/1wke) | TRNA-GUANINE TRANSGLYCOSYLASE | Descriptor: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | Authors: | Romier, C, Reuter, K, Suck, D, Ficner, R. | Deposit date: | 1996-08-06 | Release date: | 1997-07-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile. Biochemistry, 35, 1996
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1WKF
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![BU of 1wkf by Molmil](/molmil-images/mine/1wkf) | TRNA-GUANINE TRANSGLYCOSYLASE | Descriptor: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | Authors: | Romier, C, Reuter, K, Suck, D, Ficner, R. | Deposit date: | 1996-08-06 | Release date: | 1997-07-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile. Biochemistry, 35, 1996
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8ARU
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5HSA
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![BU of 5hsa by Molmil](/molmil-images/mine/5hsa) | Alcohol Oxidase AOX1 from Pichia Pastoris | Descriptor: | ARABINO-FLAVIN-ADENINE DINUCLEOTIDE, Alcohol oxidase 1, CALCIUM ION, ... | Authors: | Neumann, P, Ficner, R, Feussner, I, Koch, C. | Deposit date: | 2016-01-25 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of Alcohol Oxidase from Pichia pastoris. Plos One, 11, 2016
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5J8N
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5D0U
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6QIE
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![BU of 6qie by Molmil](/molmil-images/mine/6qie) | Crystal structure of DEAH-box ATPase Prp43-S387G | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Hamann, F, Ficner, R, Enders, M. | Deposit date: | 2019-01-18 | Release date: | 2019-03-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for RNA translocation by DEAH-box ATPases. Nucleic Acids Res., 47, 2019
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6QIC
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6QID
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![BU of 6qid by Molmil](/molmil-images/mine/6qid) | Crystal structure of DEAH-box ATPase Prp43-S387A | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Hamann, F, Ficner, R, Enders, M. | Deposit date: | 2019-01-18 | Release date: | 2019-03-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Structural basis for RNA translocation by DEAH-box ATPases. Nucleic Acids Res., 47, 2019
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1F3E
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![BU of 1f3e by Molmil](/molmil-images/mine/1f3e) | A NEW TARGET FOR SHIGELLOSIS: RATIONAL DESIGN AND CRYSTALLOGRAPHIC STUDIES OF INHIBITORS OF TRNA-GUANINE TRANSGLYCOSYLASE | Descriptor: | 3,5-DIAMINOPHTHALHYDRAZIDE, QUEUINE TRNA-RIBOSYLTRANSFERASE, ZINC ION | Authors: | Graedler, U, Gerber, H.-D, Goodenough-Lashua, D.M, Garcia, G.A.G, Ficner, R, Reuter, K, Stubbs, M.T, Klebe, G. | Deposit date: | 2000-06-02 | Release date: | 2000-06-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase. J.Mol.Biol., 306, 2001
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1FJH
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![BU of 1fjh by Molmil](/molmil-images/mine/1fjh) | THE CRYSTAL STRUCTURE OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY | Descriptor: | 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE | Authors: | Grimm, C, Ficner, R, Maser, E, Klebe, G, Reuter, K. | Deposit date: | 2000-08-08 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family. J.Biol.Chem., 275, 2000
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1FK8
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![BU of 1fk8 by Molmil](/molmil-images/mine/1fk8) | THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX WITH NAD OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY | Descriptor: | 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Grimm, C, Ficner, R, Maser, E, Klebe, G, Reuter, K. | Deposit date: | 2000-08-09 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family. J.Biol.Chem., 275, 2000
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2GH6
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![BU of 2gh6 by Molmil](/molmil-images/mine/2gh6) | Crystal structure of a HDAC-like protein with 9,9,9-trifluoro-8-oxo-N-phenylnonan amide bound | Descriptor: | 9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... | Authors: | Nielsen, T.K, Hildmann, C, Riester, D, Wegener, D, Schwienhorst, A, Ficner, R. | Deposit date: | 2006-03-26 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.203 Å) | Cite: | Complex structure of a bacterial class 2 histone deacetylase homologue with a trifluoromethylketone inhibitor. Acta Crystallogr.,Sect.F, 63, 2007
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1QR0
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![BU of 1qr0 by Molmil](/molmil-images/mine/1qr0) | CRYSTAL STRUCTURE OF THE 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP-COENZYME A COMPLEX | Descriptor: | 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP, COENZYME A, MAGNESIUM ION | Authors: | Reuter, K, Mofid, R.M, Marahiel, A.M, Ficner, R. | Deposit date: | 1999-06-17 | Release date: | 1999-12-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily. EMBO J., 18, 1999
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1ALL
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![BU of 1all by Molmil](/molmil-images/mine/1all) | ALLOPHYCOCYANIN | Descriptor: | ALLOPHYCOCYANIN, PHYCOCYANOBILIN | Authors: | Brejc, K, Ficner, R, Huber, R, Steinbacher, S. | Deposit date: | 1995-03-01 | Release date: | 1996-07-11 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Isolation, crystallization, crystal structure analysis and refinement of allophycocyanin from the cyanobacterium Spirulina platensis at 2.3 A resolution. J.Mol.Biol., 249, 1995
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3JU4
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![BU of 3ju4 by Molmil](/molmil-images/mine/3ju4) | Crystal Structure Analysis of EndosialidaseNF at 0.98 A Resolution | Descriptor: | CHLORIDE ION, Endo-N-acetylneuraminidase, N-acetyl-beta-neuraminic acid, ... | Authors: | Schulz, E.C, Neuman, P, Gerardy-Schahn, R, Sheldrick, G.M, Ficner, R. | Deposit date: | 2009-09-14 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Structure analysis of endosialidase NF at 0.98 A resolution. Acta Crystallogr.,Sect.D, 66, 2010
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7NQ4
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6YJ8
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![BU of 6yj8 by Molmil](/molmil-images/mine/6yj8) | DarB-APO | Descriptor: | ACETATE ION, CBS domain-containing protein YkuL, DI(HYDROXYETHYL)ETHER | Authors: | Heidemann, J.L, Neumann, P, Ficner, R. | Deposit date: | 2020-04-02 | Release date: | 2021-04-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | DarB from B. subtilis To Be Published
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