1F3E
A NEW TARGET FOR SHIGELLOSIS: RATIONAL DESIGN AND CRYSTALLOGRAPHIC STUDIES OF INHIBITORS OF TRNA-GUANINE TRANSGLYCOSYLASE
Summary for 1F3E
Entry DOI | 10.2210/pdb1f3e/pdb |
Related | 1EFZ 1ENU 1PUD |
Descriptor | QUEUINE TRNA-RIBOSYLTRANSFERASE, ZINC ION, 3,5-DIAMINOPHTHALHYDRAZIDE, ... (4 entities in total) |
Functional Keywords | trna-modifying enzyme, glycosyltransferase, transferase |
Biological source | Zymomonas mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43183.29 |
Authors | Graedler, U.,Gerber, H.-D.,Goodenough-Lashua, D.M.,Garcia, G.A.G.,Ficner, R.,Reuter, K.,Stubbs, M.T.,Klebe, G. (deposition date: 2000-06-02, release date: 2000-06-15, Last modification date: 2024-02-07) |
Primary citation | Gradler, U.,Gerber, H.D.,Goodenough-Lashua, D.M.,Garcia, G.A.,Ficner, R.,Reuter, K.,Stubbs, M.T.,Klebe, G. A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase. J.Mol.Biol., 306:455-467, 2001 Cited by PubMed: 11178905DOI: 10.1006/jmbi.2000.4256 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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