8A4L
| Lipidic alpha-synuclein fibril - polymorph L2A | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-06-12 | Release date: | 2022-08-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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6GEZ
| THE STRUCTURE OF TWITCH-2B N532F | Descriptor: | CALCIUM ION, FORMIC ACID, Green fluorescent protein,Optimized Ratiometric Calcium Sensor,Green fluorescent protein,Green fluorescent protein | Authors: | Trigo Mourino, P, Paulat, M, Thestrup, T, Griesbeck, O, Griesinger, C, Becker, S. | Deposit date: | 2018-04-27 | Release date: | 2019-08-21 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Dynamic tuning of FRET in a green fluorescent protein biosensor. Sci Adv, 5, 2019
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2Y0R
| Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 | Descriptor: | MYOSIN-2 HEAVY CHAIN | Authors: | Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. | Deposit date: | 2010-12-07 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
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2Y8I
| Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN-2 HEAVY CHAIN | Authors: | Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. | Deposit date: | 2011-02-07 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.132 Å) | Cite: | Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
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5NWX
| Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6 | Descriptor: | Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6 | Authors: | Russo, L, Giller, K, Pfitzner, E, Griesinger, C, Becker, S. | Deposit date: | 2017-05-08 | Release date: | 2017-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6. Sci Rep, 7, 2017
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6GEL
| The structure of TWITCH-2B | Descriptor: | CALCIUM ION, FORMIC ACID, GLYCEROL, ... | Authors: | Trigo Mourino, P, Paulat, M, Thestrup, T, Griesbeck, O, Griesinger, C, Becker, S. | Deposit date: | 2018-04-26 | Release date: | 2019-08-21 | Last modified: | 2019-09-11 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Dynamic tuning of FRET in a green fluorescent protein biosensor. Sci Adv, 5, 2019
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2JK4
| Structure of the human voltage-dependent anion channel | Descriptor: | VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1 | Authors: | Bayrhuber, M, Meins, T, Habeck, M, Becker, S, Giller, K, Villinger, S, Vonrhein, C, Griesinger, C, Zweckstetter, M, Zeth, K. | Deposit date: | 2008-08-15 | Release date: | 2008-10-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structure of the Human Voltage-Dependent Anion Channel. Proc.Natl.Acad.Sci.USA, 105, 2008
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5JDP
| E73V mutant of the human voltage-dependent anion channel | Descriptor: | Voltage-dependent anion-selective channel protein 1 | Authors: | Jaremko, M, Jaremko, L, Villinger, S, Schmidt, C, Giller, K, Griesinger, C, Becker, S, Zweckstetter, M. | Deposit date: | 2016-04-17 | Release date: | 2016-08-10 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | High-Resolution NMR Determination of the Dynamic Structure of Membrane Proteins. Angew.Chem.Int.Ed.Engl., 55, 2016
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8P7K
| The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | Descriptor: | (2~{R})-2-methylpentanedioic acid, FORMIC ACID, Parathion hydrolase, ... | Authors: | Dym, O, Aggawal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | Deposit date: | 2023-05-30 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.929 Å) | Cite: | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase. Acta Crystallogr D Struct Biol, 79, 2023
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1G8X
| STRUCTURE OF A GENETICALLY ENGINEERED MOLECULAR MOTOR | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN II HEAVY CHAIN FUSED TO ALPHA-ACTININ 3 | Authors: | Kliche, W, Fujita-Becker, S, Kollmar, M, Manstein, D.J, Kull, F.J. | Deposit date: | 2000-11-21 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of a genetically engineered molecular motor. EMBO J., 20, 2001
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5FQ1
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7O4D
| QR2 inhibitor from a novel sulfanamide series to tackle age related oxidative stress and cognitive decline | Descriptor: | 8-methyl-2-(4-methyl-3-piperazin-1-ylsulfonyl-phenyl)imidazo[1,2-a]pyridine, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | Authors: | Gould, N.L, Scherer, G.R, Carvalh, S, Shurrush, K, Edry, E, Elkobi, A, David, O, Dym, O, Albeck, S, Peleg, Y, Germain, N, Babaev, I, Sharir, H, Lefker, B, Subramanyam, C, Barr, H, Rosenblum, K. | Deposit date: | 2021-04-06 | Release date: | 2022-08-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.249 Å) | Cite: | Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice. J.Clin.Invest., 133, 2023
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5ABS
| CRYSTAL STRUCTURE OF THE C-TERMINAL COILED-COIL DOMAIN OF CIN85 IN SPACE GROUP P321 | Descriptor: | SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1, ZINC ION | Authors: | Wong, L, Habeck, M, Griesinger, C, Becker, S. | Deposit date: | 2015-08-07 | Release date: | 2016-07-13 | Last modified: | 2019-02-06 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The Adaptor Protein Cin85 Assembles Intracellular Signaling Clusters for B Cell Activation. Sci.Signal., 9, 2016
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1Y1U
| Structure of unphosphorylated STAT5a | Descriptor: | Signal transducer and activator of transcription 5A | Authors: | Neculai, D, Neculai, A.M, Verrier, S, Straub, K, Klumpp, K, Pfitzner, E, Becker, S. | Deposit date: | 2004-11-19 | Release date: | 2005-10-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Structure of the unphosphorylated STAT5a dimer J.Biol.Chem., 280, 2005
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2V8Z
| Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12 | Descriptor: | YAGE | Authors: | Manicka, S, Peleg, Y, Unger, T, Albeck, S, Dym, O, Greenblatt, H.M, Bourenkov, G, Lamzin, V, Krishnaswamy, S, Sussman, J.L. | Deposit date: | 2007-08-16 | Release date: | 2008-03-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Yage, a Putative Dhdps Like Protein from Escherichia Coli K12. Proteins: Struct., Funct., Bioinf., 71, 2008
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1UTX
| Regulation of Cytolysin Expression by Enterococcus faecalis: Role of CylR2 | Descriptor: | CYLR2, IODIDE ION, SODIUM ION | Authors: | Razeto, A, Rumpel, S, Pillar, C.M, Gilmore, M.S, Becker, S, Zweckstetter, M. | Deposit date: | 2003-12-12 | Release date: | 2004-09-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and DNA-Binding Properties of the Cytolysin Regulator CylR2 from Enterococcus Faecalis Embo J., 23, 2004
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2V9D
| Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12 | Descriptor: | YAGE | Authors: | Manicka, S, Peleg, Y, Unger, T, Albeck, S, Dym, O, Greenblatt, H.M, Bourenkov, G, Lamzin, V, Krishnaswamy, S, Sussman, J.L. | Deposit date: | 2007-08-23 | Release date: | 2008-03-04 | Last modified: | 2019-11-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structure of Yage, a Putative Dhdps Like Protein from Escherichia Coli K12. Proteins: Struct., Funct., Bioinf., 71, 2008
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3GWH
| Crystallographic Ab Initio protein solution far below atomic resolution | Descriptor: | PHOSPHATE ION, Transcriptional antiterminator (BglG family) | Authors: | Rodriguez, D.D, Grosse, C, Himmel, S, Gonzalez, C, Becker, S, Sheldrick, G.M, Uson, I. | Deposit date: | 2009-04-01 | Release date: | 2010-04-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystallographic ab initio protein structure solution below atomic resolution Nat.Methods, 6, 2009
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2N64
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2YAT
| Crystal structure of estradiol derived metal chelate and estrogen receptor-ligand binding domain complex | Descriptor: | ESTRADIOL-PYRIDINIUM TETRAACETIC ACID, ESTROGEN RECEPTOR, EUROPIUM ION, ... | Authors: | Li, M.J, Greenblatt, H.M, Dym, O, Albeck, S, Degani, H, Sussman, J.L. | Deposit date: | 2011-02-24 | Release date: | 2011-06-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Structure of Estradiol Metal Chelate and Estrogen Receptor Complex: The Basis for Designing a New Class of Selective Estrogen Receptor Modulators. J.Med.Chem., 54, 2011
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3BTP
| Crystal structure of Agrobacterium tumefaciens VirE2 in complex with its chaperone VirE1: a novel fold and implications for DNA binding | Descriptor: | AMMONIUM ION, DI(HYDROXYETHYL)ETHER, Protein virE1, ... | Authors: | Dym, O, Albeck, S, Unger, T, Elbaum, M, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2007-12-30 | Release date: | 2008-08-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the Agrobacterium virulence complex VirE1-VirE2 reveals a flexible protein that can accommodate different partners. Proc.Natl.Acad.Sci.Usa, 105, 2008
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8P7I
| The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | Descriptor: | (2~{S},6~{R})-2,6-dimethyl-1,3-dioxane-4,4-diol, FORMIC ACID, Parathion hydrolase, ... | Authors: | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | Deposit date: | 2023-05-30 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase. Acta Crystallogr D Struct Biol, 79, 2023
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8P7N
| The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | Descriptor: | FORMIC ACID, Parathion hydrolase, ZINC ION | Authors: | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | Deposit date: | 2023-05-30 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase. Acta Crystallogr D Struct Biol, 79, 2023
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8P7T
| The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | Descriptor: | 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, GLYCEROL, ... | Authors: | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | Deposit date: | 2023-05-31 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase. Acta Crystallogr D Struct Biol, 79, 2023
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8P7V
| The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | Descriptor: | 1,2-ETHANEDIOL, 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, ... | Authors: | Dym, O, Aggawal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | Deposit date: | 2023-05-31 | Release date: | 2023-10-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.737 Å) | Cite: | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase. Acta Crystallogr D Struct Biol, 79, 2023
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