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2B6O
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BU of 2b6o by Molmil
Electron crystallographic structure of lens Aquaporin-0 (AQP0) (lens MIP) at 1.9A resolution, in a closed pore state
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Lens fiber major intrinsic protein
Authors:Gonen, T, Cheng, Y, Sliz, P, Hiroaki, Y, Fujiyoshi, Y, Harrison, S.C, Walz, T.
Deposit date:2005-10-03
Release date:2005-12-06
Last modified:2023-08-23
Method:ELECTRON CRYSTALLOGRAPHY (1.9 Å)
Cite:Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
2D57
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BU of 2d57 by Molmil
Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography
Descriptor: Aquaporin-4
Authors:Hiroaki, Y, Tani, K, Kamegawa, A, Gyobu, N, Nishikawa, K, Suzuki, H, Walz, T, Sasaki, S, Mitsuoka, K, Kimura, K, Mizoguchi, A, Fujiyoshi, Y.
Deposit date:2005-10-29
Release date:2006-01-31
Last modified:2023-11-08
Method:ELECTRON CRYSTALLOGRAPHY (3.2 Å)
Cite:Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion
J.Mol.Biol., 355, 2005
5GLH
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BU of 5glh by Molmil
Human endothelin receptor type-B in complex with ET-1
Descriptor: Endothelin Receptor Subtype-B, Peptide from Endothelin-1
Authors:Shihoya, W, Nishizawa, T, Okuta, A, Tani, K, Fujiyoshi, Y, Dohmae, N, Nureki, O, Doi, T.
Deposit date:2016-07-11
Release date:2016-09-07
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Activation mechanism of endothelin ETB receptor by endothelin-1.
Nature, 537, 2016
5H1R
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BU of 5h1r by Molmil
C. elegans INX-6 gap junction channel
Descriptor: Innexin-6
Authors:Oshima, A, Tani, K, Fujiyoshi, Y.
Deposit date:2016-10-11
Release date:2016-12-07
Last modified:2017-02-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Atomic structure of the innexin-6 gap junction channel determined by cryo-EM
Nat Commun, 7, 2016
5GLI
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BU of 5gli by Molmil
Human endothelin receptor type-B in the ligand-free form
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Endothelin Receptor Subtype-B, OLEIC ACID, ...
Authors:Shihoya, W, Nishizawa, T, Okuta, A, Tani, K, Fujiyoshi, Y, Dohmae, N, Nureki, O, Doi, T.
Deposit date:2016-07-11
Release date:2016-09-07
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Activation mechanism of endothelin ETB receptor by endothelin-1.
Nature, 537, 2016
5H1Q
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BU of 5h1q by Molmil
C. elegans INX-6 gap junction hemichannel
Descriptor: Innexin-6
Authors:Oshima, A, Tani, K, Fujiyoshi, Y.
Deposit date:2016-10-11
Release date:2016-12-07
Last modified:2017-02-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Atomic structure of the innexin-6 gap junction channel determined by cryo-EM
Nat Commun, 7, 2016
8GCL
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BU of 8gcl by Molmil
Cryo-EM structure of hAQP2 in DDM
Descriptor: Aquaporin-2
Authors:Kamegawa, A, Suzuki, S, Nishikawa, K, Numoto, N, Suzuki, H, Fujiyoshi, Y.
Deposit date:2023-03-02
Release date:2023-06-21
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural analysis of the water channel AQP2 by single-particle cryo-EM.
J.Struct.Biol., 215, 2023
8HUJ
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BU of 8huj by Molmil
Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A
Descriptor: Eukaryotic initiation factor 4A-I, Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), ...
Authors:Suzuki, H, Fujiyoshi, Y, Imai, S, Shimada, I.
Deposit date:2022-12-24
Release date:2023-08-02
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor.
Nat Commun, 14, 2023
8IHI
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BU of 8ihi by Molmil
Cryo-EM structure of HCA2-Gi complex with acifran
Descriptor: (5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y.
Deposit date:2023-02-22
Release date:2023-08-30
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding.
Nat Commun, 14, 2023
8IHF
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BU of 8ihf by Molmil
Cryo-EM structure of HCA2-Gi complex with MK6892
Descriptor: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y.
Deposit date:2023-02-22
Release date:2023-08-30
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding.
Nat Commun, 14, 2023
8IHB
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BU of 8ihb by Molmil
Cryo-EM structure of HCA2-Gi complex with GSK256073
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y.
Deposit date:2023-02-22
Release date:2023-09-13
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding.
Nat Commun, 14, 2023
3VOU
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BU of 3vou by Molmil
The crystal structure of NaK-NavSulP chimera channel
Descriptor: COBALT (II) ION, Ion transport 2 domain protein, Voltage-gated sodium channel, ...
Authors:Irie, K, Shimomura, T, Fujiyoshi, Y.
Deposit date:2012-02-10
Release date:2012-05-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate
Nat Commun, 3, 2012
8J7R
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BU of 8j7r by Molmil
Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A (J-K-St/eIF4G focused)
Descriptor: Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), MAGNESIUM ION
Authors:Suzuki, H, Fujiyoshi, Y, Imai, S, Shimada, I.
Deposit date:2023-04-28
Release date:2023-08-02
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor.
Nat Commun, 14, 2023
8IHJ
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BU of 8ihj by Molmil
Cryo-EM structure of HCA3-Gi complex with acifran
Descriptor: (5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y.
Deposit date:2023-02-22
Release date:2023-08-30
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding.
Nat Commun, 14, 2023
8IHH
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BU of 8ihh by Molmil
Cryo-EM structure of HCA2-Gi complex with LUF6283
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-butyl-1~{H}-pyrazole-3-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y.
Deposit date:2023-02-22
Release date:2023-08-30
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding.
Nat Commun, 14, 2023
8IHK
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BU of 8ihk by Molmil
Cryo-EM structure of HCA3-Gi complex with acifran (local)
Descriptor: (5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid, Soluble cytochrome b562,Hydroxycarboxylic acid receptor 3
Authors:Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y.
Deposit date:2023-02-22
Release date:2023-08-30
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding.
Nat Commun, 14, 2023
4AQ5
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BU of 4aq5 by Molmil
Gating movement in acetylcholine receptor analysed by time-resolved electron cryo-microscopy (closed class)
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Unwin, N, Fujiyoshi, Y.
Deposit date:2012-04-12
Release date:2012-08-01
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing.
J.Mol.Biol., 422, 2012
4AQ9
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BU of 4aq9 by Molmil
Gating movement in acetylcholine receptor analysed by time- resolved electron cryo-microscopy (open class)
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Unwin, N, Fujiyoshi, Y.
Deposit date:2012-04-13
Release date:2012-08-01
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing.
J.Mol.Biol., 422, 2012
2XZB
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BU of 2xzb by Molmil
Pig Gastric H,K-ATPase with bound BeF and SCH28080
Descriptor: POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA
Authors:Abe, K, Tani, K, Fujiyoshi, Y.
Deposit date:2010-11-24
Release date:2011-01-26
Last modified:2020-09-16
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Conformational Rearrangement of Gastric H(+),K(+)- ATPase Induced by an Acid Suppressant.
Nat.Commun., 2, 2011
2ZW3
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BU of 2zw3 by Molmil
Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution
Descriptor: Gap junction beta-2 protein
Authors:Maeda, S, Nakagawa, S, Suga, M, Yamashita, E, Oshima, A, Fujiyoshi, Y, Tsukihara, T.
Deposit date:2008-12-01
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the connexin 26 gap junction channel at 3.5 A resolution
Nature, 458, 2009
2YN9
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BU of 2yn9 by Molmil
Cryo-EM structure of gastric H+,K+-ATPase with bound rubidium
Descriptor: POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA
Authors:Abe, K, Tani, K, Friedrich, T, Fujiyoshi, Y.
Deposit date:2012-10-13
Release date:2012-11-07
Last modified:2014-07-16
Method:ELECTRON CRYSTALLOGRAPHY (8 Å)
Cite:Cryo-Em Structure of Gastric H+,K+-ATPase with a Single Occupied Cation-Binding Site.
Proc.Natl.Acad.Sci.USA, 109, 2012
5YUA
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BU of 5yua by Molmil
Crystal structure of voltage-gated sodium channel NavAb in high-pH condition
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, CHAPSO, ...
Authors:Irie, K, Shimomura, T, Fujiyoshi, Y.
Deposit date:2017-11-21
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.80085564 Å)
Cite:Structural insight on the voltage dependence of prokaryotic voltage gated sodium channel NavAb.
FEBS Lett., 2017
5YUC
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BU of 5yuc by Molmil
Crystal structure of voltage-gated sodium channel NavAb N49K mutant
Descriptor: CALCIUM ION, CHAPSO, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Irie, K, Shimomura, T, Fujiyoshi, Y.
Deposit date:2017-11-21
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.40099168 Å)
Cite:Structural insight on the voltage dependence of prokaryotic voltage gated sodium channel NavAb.
FEBS Lett., 2017
5YUB
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BU of 5yub by Molmil
Crystal structure of voltage-gated sodium channel NavAb E32Q mutant
Descriptor: CALCIUM ION, CHAPSO, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Irie, K, Shimomura, T, Fujiyoshi, Y.
Deposit date:2017-11-21
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.40004 Å)
Cite:Structural insight on the voltage dependence of prokaryotic voltage gated sodium channel NavAb.
FEBS Lett., 2017
6AKF
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BU of 6akf by Molmil
Crystal structure of mouse claudin-3 P134A mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin
Descriptor: Claudin-3, Heat-labile enterotoxin B chain
Authors:Nakamura, S, Irie, K, Fujiyoshi, Y.
Deposit date:2018-08-31
Release date:2019-02-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Morphologic determinant of tight junctions revealed by claudin-3 structures.
Nat Commun, 10, 2019

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