3N3T
| Crystal structure of putative diguanylate cyclase/phosphodiesterase complex with cyclic di-gmp | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Chang, C, Xu, X, Cui, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-05-20 | Release date: | 2010-06-16 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases. J.Mol.Biol., 402, 2010
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3N7Z
| Crystal structure of acetyltransferase from Bacillus anthracis | Descriptor: | Acetyltransferase, GNAT family, SODIUM ION | Authors: | Chang, C, Wu, R, Gornicki, P, Zhang, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-05-27 | Release date: | 2010-06-16 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis. Biochemistry, 54, 2015
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4TKT
| Streptomyces platensis isomigrastatin ketosynthase domain MgsF KS6 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AT-less polyketide synthase, CHLORIDE ION, ... | Authors: | Chang, C, Li, H, Endres, M, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2014-05-27 | Release date: | 2014-06-11 | Last modified: | 2023-03-22 | Method: | X-RAY DIFFRACTION (2.4289 Å) | Cite: | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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2R6O
| Crystal structure of putative diguanylate cyclase/phosphodiesterase from Thiobacillus denitrificans | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) | Authors: | Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-09-06 | Release date: | 2007-09-18 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases. J.Mol.Biol., 402, 2010
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4EY3
| Crystal structure of solute binding protein of ABC transporter in complex with p-hydroxybenzoic acid | Descriptor: | P-HYDROXYBENZOIC ACID, Twin-arginine translocation pathway signal | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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4EYG
| Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris BisB5 in complex with vanillic acid | Descriptor: | 1,2-ETHANEDIOL, 4-HYDROXY-3-METHOXYBENZOATE, ISOPROPYL ALCOHOL, ... | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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2AG8
| NADP complex of Pyrroline-5-carboxylate reductase from Neisseria meningitidis | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, pyrroline-5-carboxylate reductase | Authors: | Chang, C, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-07-26 | Release date: | 2005-09-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes. J.Mol.Biol., 354, 2005
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1TD4
| Crystal structure of VSHP_BPP21 in space group H3 with high resolution. | Descriptor: | Head decoration protein | Authors: | Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A. | Deposit date: | 2004-05-21 | Release date: | 2004-11-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP. J.Mol.Biol., 344, 2004
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1TD0
| Viral capsid protein SHP at pH 5.5 | Descriptor: | Head decoration protein | Authors: | Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A. | Deposit date: | 2004-05-21 | Release date: | 2004-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP J.Mol.Biol., 344, 2004
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1TD3
| Crystal structure of VSHP_BPP21 in space group C2 | Descriptor: | Head decoration protein | Authors: | Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A. | Deposit date: | 2004-05-21 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP. J.Mol.Biol., 344, 2004
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1U60
| MCSG APC5046 Probable glutaminase ybaS | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, Probable glutaminase ybaS | Authors: | Chang, C, Cuff, M.E, Joachimiak, A, Savchenko, A, Edwards, A, Skarina, T, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-07-28 | Release date: | 2004-09-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis. Biochemistry, 47, 2008
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1YQG
| Crystal structure of a pyrroline-5-carboxylate reductase from neisseria meningitides mc58 | Descriptor: | SULFATE ION, pyrroline-5-carboxylate reductase | Authors: | Chang, C, Joachimiak, A, Li, H, Collart, F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-02-01 | Release date: | 2005-02-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes J.Mol.Biol., 354, 2005
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5W27
| Crystal structure of TnmS3 in complex with tiancimycin (TNM B) | Descriptor: | Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate | Authors: | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, SHen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-06-05 | Release date: | 2018-06-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of TnmS3 in complex with tiancimycin (TNM B) To Be Published
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1VJS
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2G7S
| The crystal structure of transcriptional regulator, TetR family, from Agrobacterium tumefaciens | Descriptor: | transcriptional regulator, TetR family | Authors: | Lunin, V.V, Chang, C, Xu, X, Gu, J, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-02-28 | Release date: | 2006-03-14 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The crystal structure of transcriptional regulator, TetR family, from Agrobacterium tumefaciens To be Published
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1HYE
| CRYSTAL STRUCTURE OF THE MJ0490 GENE PRODUCT, THE FAMILY OF LACTATE/MALATE DEHYDROGENASE, DIMERIC STRUCTURE | Descriptor: | L-LACTATE/MALATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Lee, B.I, Chang, C, Cho, S.-J, Suh, S.W. | Deposit date: | 2001-01-19 | Release date: | 2001-04-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases. J.Mol.Biol., 307, 2001
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1HYG
| Crystal structure of MJ0490 gene product, the family of lactate/malate dehydrogenase | Descriptor: | L-LACTATE/MALATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Lee, B.I, Chang, C, Cho, S.-J, Suh, S.W. | Deposit date: | 2001-01-19 | Release date: | 2001-04-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases J.Mol.Biol., 307, 2001
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6XIN
| The crystal structure of tryptophan synthase from Salmonella enterica serovar typhimurium in complex with (2S)-3-Amino-3-imino-2-phenyldiazenylpropanamide at the enzyme alpha-site. | Descriptor: | (2R,3Z)-3-amino-3-imino-2-[(E)-phenyldiazenyl]propanamide, 1,2-ETHANEDIOL, CESIUM ION, ... | Authors: | Hilario, E, Chang, C, Mueller, L.J, Dunn, M.F, Fan, L. | Deposit date: | 2020-06-20 | Release date: | 2021-06-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The crystal structure of tryptophan synthase from Salmonella enterica serovar typhimurium in complex with (2S)-3-Amino-3-imino-2-phenyldiazenylpropanamide at the enzyme alpha-site. To Be Published
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5UMY
| Crystal structure of TnmS3 in complex with tiancimycin | Descriptor: | (1aS,11S,11aR,14Z,18R)-3,8,18-trihydroxy-11a-[(1R)-1-hydroxyethyl]-7-methoxy-11,11a-dihydro-4H-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinoline-4,9(10H)-dione, Glyoxalase/bleomycin resisance protein/dioxygenase | Authors: | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, SHen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-01-29 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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5UMQ
| Crystal structure of TnmS1, an antibiotic binding protein from Streptomyces sp. CB03234 | Descriptor: | Glyoxalase/bleomycin resisance protein/dioxygenase | Authors: | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-01-29 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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5UMX
| Crystal structure of TnmS3 in complex with riboflavin | Descriptor: | Glyoxalase/bleomycin resisance protein/dioxygenase, RIBOFLAVIN | Authors: | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-01-29 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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5UMP
| Crystal structure of TnmS3, an antibiotic binding protein from Streptomyces sp. CB03234 | Descriptor: | Glyoxalase/bleomycin resisance protein/dioxygenase | Authors: | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-01-29 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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5UMW
| Crystal structure of TnmS2, an antibiotic binding protein from Streptomyces sp. CB03234 | Descriptor: | Glyoxalase/bleomycin resisance protein/dioxygenase, RIBOFLAVIN | Authors: | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-01-29 | Release date: | 2018-07-04 | Last modified: | 2020-09-23 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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8FDS
| Ankyrin domain of SKD3 isoform 2 | Descriptor: | Caseinolytic peptidase B protein homolog, FORMIC ACID | Authors: | Lee, S, Tsai, F.T.F, Chang, C. | Deposit date: | 2022-12-04 | Release date: | 2023-04-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria. Nat Commun, 14, 2023
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6X1B
| Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with the Product Nucleotide GpU. | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-R(*GP*U)-3'), PHOSPHATE ION, ... | Authors: | Kim, Y, Maltseva, N, Jedrzejczak, R, Welk, L, Endres, M, Chang, C, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-05-18 | Release date: | 2020-05-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2. Commun Biol, 4, 2021
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