7W5Y
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7W5W
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7W5X
| Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Lin, W, Feng, Y, Shi, J. | Deposit date: | 2021-11-30 | Release date: | 2022-10-26 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of three different transcription activation strategies adopted by a single regulator SoxS. Nucleic Acids Res., 50, 2022
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7ELM
| Structure of Csy-AcrIF24 | Descriptor: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | Authors: | Zhang, L, Feng, Y. | Deposit date: | 2021-04-12 | Release date: | 2022-04-20 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
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7ELN
| Structure of Csy-AcrIF24-dsDNA | Descriptor: | 54-MER DNA, AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, ... | Authors: | Zhang, L, Feng, Y. | Deposit date: | 2021-04-12 | Release date: | 2022-04-20 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
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7EQG
| Structure of Csy-AcrIF5 | Descriptor: | AcrIF5, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | Authors: | Zhang, L, Feng, Y. | Deposit date: | 2021-05-01 | Release date: | 2022-03-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition. Nat.Chem.Biol., 18, 2022
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8HSY
| Acyl-ACP Synthetase structure | Descriptor: | Acyl-acyl carrier protein synthetase | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2022-12-20 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.53 Å) | Cite: | Acyl-ACP Synthetase structure To Be Published
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7EGN
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine | Descriptor: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, ... | Authors: | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | Deposit date: | 2021-03-24 | Release date: | 2021-08-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | H-Bonding Networks Dictate the Molecular Mechanism of H2O2 Activation by P450 Acs Catalysis, 11, 2021
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8I22
| Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | Descriptor: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-01-13 | Release date: | 2024-01-17 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester To Be Published
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8I51
| Acyl-ACP synthetase structure bound to AMP-MC7 | Descriptor: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, ... | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-01-21 | Release date: | 2024-01-24 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Acyl-ACP synthetase structure bound to AMP-MC7 To Be Published
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8I35
| Acyl-ACP synthetase structure bound to oleic acid | Descriptor: | Acyl-acyl carrier protein synthetase, OLEIC ACID | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-01-16 | Release date: | 2024-01-24 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Acyl-ACP synthetase structure bound to oleic acid To Be Published
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8I3I
| Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2 | Descriptor: | Acyl-acyl carrier protein synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-01-17 | Release date: | 2024-01-24 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2 To Be Published
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8I6M
| Acyl-ACP synthetase structure bound to AMP-C18:1 | Descriptor: | ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, MAGNESIUM ION, ... | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-01-28 | Release date: | 2024-01-31 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Acyl-ACP synthetase structure bound to AMP-C18:1 To Be Published
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8I49
| Acyl-ACP synthetase structure bound to ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-acyl carrier protein synthetase | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-01-18 | Release date: | 2024-01-24 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | Acyl-ACP synthetase structure bound to ATP. To Be Published
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8HZX
| Acyl-ACP synthetase structure-2 | Descriptor: | Acyl-acyl carrier protein synthetase | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-01-09 | Release date: | 2024-01-24 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Acyl-ACP synthetase structure-2 To Be Published
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8I8D
| Acyl-ACP synthetase structure bound to MC7-ACP | Descriptor: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ... | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-02-03 | Release date: | 2024-02-07 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Acyl-ACP synthetase structure bound to MC7-ACP To Be Published
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8I8E
| Acyl-ACP synthetase structure bound to C18:1-ACP | Descriptor: | 4'-PHOSPHOPANTETHEINE, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ... | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | Deposit date: | 2023-02-04 | Release date: | 2024-02-07 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | Acyl-ACP synthetase structure bound to C18:1-ACP To Be Published
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8IVY
| Beta-Glucosidase BglA mutant E166Q in complex with glucose | Descriptor: | Beta-glucosidase, GLYCEROL, beta-D-glucopyranose | Authors: | Dong, S, Xiao, Y, Feng, Y. | Deposit date: | 2023-03-29 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Key roles of beta-glucosidase BglA for the catabolism of both laminaribiose and cellobiose in the lignocellulolytic bacterium Clostridium thermocellum. Int.J.Biol.Macromol., 250, 2023
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8KBE
| Structure of CbTad1 complexed with 1',3'-cADPR | Descriptor: | (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, Thoeris anti-defense 1 | Authors: | Xiao, Y, Feng, Y. | Deposit date: | 2023-08-04 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Structure of CbTad1 complexed with 1',3'-cADPR To Be Published
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8KBF
| Structure of CbTad1 complexed with 1',3'-cADPR and cA3 | Descriptor: | (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE, (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, Thoeris anti-defense 1 | Authors: | Xiao, Y, Feng, Y. | Deposit date: | 2023-08-04 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structure of CbTad1 complexed with 1',3'-cADPR and cA3 To Be Published
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8KBK
| Structure of AcrIIA7 complexed with 1',2'-cADPR and cGG | Descriptor: | (1S,3R,4R,6R,9S,11R,14R,15S,16R,18R)-4-(6-amino-9H-purin-9-yl)-9,11,15,16,18-pentahydroxy-2,5,8,10,12,17-hexaoxa-9lambda~5~,11lambda~5~-diphosphatricyclo[12.2.1.1~3,6~]octadecane-9,11-dione, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Inhibitor of Type II CRISPR-Cas system | Authors: | Xiao, Y, Feng, Y. | Deposit date: | 2023-08-04 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structure of AcrIIA7 complexed with 1',2'-cADPR and cGG To Be Published
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8KBB
| Structure of apo-CmTad1 | Descriptor: | Thoeris anti-defense 1, ZINC ION | Authors: | Xiao, Y, Feng, Y. | Deposit date: | 2023-08-04 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structure of apo-CmTad1 To Be Published
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8KBL
| Structure of AcrIIA7 complexed with 1',3'-cADPR and cGG | Descriptor: | (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Inhibitor of Type II CRISPR-Cas system | Authors: | Xiao, Y, Feng, Y. | Deposit date: | 2023-08-04 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure of AcrIIA7 complexed with 1',3'-cADPR and cGG To Be Published
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8KBD
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8KBI
| Structure of apo-AcrIIA7 | Descriptor: | Inhibitor of Type II CRISPR-Cas system | Authors: | Xiao, Y, Feng, Y. | Deposit date: | 2023-08-04 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of apo-AcrIIA7 To Be Published
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