7EWY
 
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7EWV
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7EX1
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7EWW
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7EWU
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7EWZ
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7EX0
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7EX6
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7EX8
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 27 | | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | Authors: | Kuang, W, Hu, Z, Gong, P. | | Deposit date: | 2021-05-26 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX9
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 28 | | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | Authors: | Kuang, W, Hu, Z, Gong, P. | | Deposit date: | 2021-05-26 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX7
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 16 | | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | Authors: | Kuang, W, Hu, Z, Gong, P. | | Deposit date: | 2021-05-26 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX2
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with L-742,001 (methyl ester form) | | Descriptor: | MANGANESE (II) ION, Replicase, methyl (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(phenylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoate | | Authors: | Kuang, W, Hu, Z, Gong, P. | | Deposit date: | 2021-05-26 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX3
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 3 | | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | Authors: | Kuang, W, Hu, Z, Gong, P. | | Deposit date: | 2021-05-26 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX4
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 5 | | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | Authors: | Kuang, W, Hu, Z, Gong, P. | | Deposit date: | 2021-05-26 | | Release date: | 2022-02-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7F3Q
 | | SARS-CoV-2 RBD in complex with A5-10 Fab and A34-2 Fab | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of A34-2 Fab, ... | | Authors: | Dou, Y, Wang, X, Liu, P, Lu, B, Wang, K. | | Deposit date: | 2021-06-16 | | Release date: | 2022-06-22 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Development of neutralizing antibodies against SARS-CoV-2, using a high-throughput single-B-cell cloning method.
Antib Ther, 6, 2023
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7DTS
 | | Crystal structure of RNase L in complex with AC40357 | | Descriptor: | 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE, PHOSPHATE ION, Ribonuclease L, ... | | Authors: | Tang, J, Huang, H. | | Deposit date: | 2021-01-06 | | Release date: | 2021-11-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery
J.Med.Chem., 65, 2022
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7ELW
 | | Crystal structure of RNase L in complex with Myricetin | | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, PHOSPHATE ION, Ribonuclease L, ... | | Authors: | Tang, J, Huang, H. | | Deposit date: | 2021-04-12 | | Release date: | 2021-11-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery
J.Med.Chem., 65, 2022
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3UGD
 | | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta | | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Protein kinase C delta type, ... | | Authors: | Shanmugasundararaj, S, Stehle, T, Miller, K.W. | | Deposit date: | 2011-11-02 | | Release date: | 2012-12-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta
Biophys.J., 103, 2012
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3UGL
 | | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta | | Descriptor: | PHOSPHATE ION, Proteine kinase C delta type, ZINC ION, ... | | Authors: | Shanmugasundararaj, S, Stehle, T, Miller, K.W. | | Deposit date: | 2011-11-02 | | Release date: | 2012-12-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.357 Å) | | Cite: | Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Biophys.J., 103, 2012
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3UFF
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3UGI
 | | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta | | Descriptor: | (methoxymethyl)cyclopropane, PHOSPHATE ION, Protein kinase C delta type, ... | | Authors: | Shanmugasundararaj, S, Stehle, T, Miller, K.W. | | Deposit date: | 2011-11-02 | | Release date: | 2012-12-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.361 Å) | | Cite: | Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta
Biophys.J., 103, 2012
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