8XON
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5XRG
| Galectin-10/Charcot-Leyden crystal protein crystal structure | Descriptor: | GLYCEROL, Galectin-10 | Authors: | Su, J. | Deposit date: | 2017-06-08 | Release date: | 2018-01-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Galectin-10: a new structural type of prototype galectin dimer and effects on saccharide ligand binding. Glycobiology, 28, 2018
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8XYA
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5XRK
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8XY7
| hPhK alpha-gamma subcomplex in active state | Descriptor: | FARNESYL, Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform, ... | Authors: | Yang, X.K, Xiao, J.Y. | Deposit date: | 2024-01-19 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024
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8XYB
| hPhK gamma-delta subcomplex in inactive state | Descriptor: | Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ... | Authors: | Yang, X.K, Xiao, J.Y. | Deposit date: | 2024-01-19 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024
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8XN4
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6IH0
| Aquifex aeolicus LpxC complex with ACHN-975 | Descriptor: | N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta -1,3-diynyl]benzamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, ... | Authors: | Li, D.Y, Fan, S, Jin, Y.Y, Zhang, C, Lv, G.X, Wu, G.T, Yang, Z.Y. | Deposit date: | 2018-09-27 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | The Complex Structure of Protein AaLpxC from Aquifex aeolicus with ACHN-975 Molecule Suggests an Inhibitory Mechanism at Atomic-Level against Gram-Negative Bacteria Molecules, 26, 2021
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8XOO
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6IN9
| Crystal structure of MucB in complex with MucA(peri) | Descriptor: | Sigma factor AlgU negative regulatory protein, Sigma factor AlgU regulatory protein MucB | Authors: | Li, S, Zhang, Q, Bartlam, M. | Deposit date: | 2018-10-24 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa. Febs J., 286, 2019
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5XRM
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5XRH
| Galectin-10/Charcot-Leyden crystal protein crystal structure | Descriptor: | Galectin-10 | Authors: | Su, J. | Deposit date: | 2017-06-08 | Release date: | 2018-01-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Galectin-10: a new structural type of prototype galectin dimer and effects on saccharide ligand binding. Glycobiology, 28, 2018
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5XRN
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5XSR
| novel orally efficacious inhibitors complexed with PARP1 | Descriptor: | 6-fluoranyl-2-(4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide, Poly [ADP-ribose] polymerase 1, SULFATE ION | Authors: | Liu, Q, Xu, Y. | Deposit date: | 2017-06-15 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors Eur J Med Chem, 145, 2018
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6IN7
| Crystal structure of AlgU in complex with MucA(cyto) | Descriptor: | NICOTINAMIDE, RNA polymerase sigma-H factor, Sigma factor AlgU negative regulatory protein | Authors: | Li, S, Zhang, Q, Bartlam, M. | Deposit date: | 2018-10-24 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa. Febs J., 286, 2019
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6J9K
| Apo-AcrIIC2 | Descriptor: | AcrIIC2, MAGNESIUM ION | Authors: | Zhu, Y.L, Gao, A, Serganov, A, Gao, P. | Deposit date: | 2019-01-23 | Release date: | 2019-03-06 | Last modified: | 2022-03-23 | Method: | X-RAY DIFFRACTION (2.234 Å) | Cite: | Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins. Mol. Cell, 74, 2019
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6J9L
| FnoBH+AcrIIC2 | Descriptor: | AcrIIC2, HNH endonuclease family protein | Authors: | Zhu, Y.L, Gao, A, Serganov, A, Gao, P. | Deposit date: | 2019-01-23 | Release date: | 2019-03-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins. Mol. Cell, 74, 2019
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8IZB
| Lysophosphatidylserine receptor GPR174-Gs complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Gong, W, Liu, G, Li, X, Zhang, X. | Deposit date: | 2023-04-06 | Release date: | 2023-11-01 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174. Plos Biol., 21, 2023
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8IZD
| Cryo-EM structure of the C26-CoA-bound Lac1-Lip1 complex | Descriptor: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Ceramide synthase LAC1, Ceramide synthase subunit LIP1, ... | Authors: | Xie, T, Fang, Q, Gong, X. | Deposit date: | 2023-04-07 | Release date: | 2023-12-13 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structure and mechanism of a eukaryotic ceramide synthase complex. Embo J., 42, 2023
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8IWT
| hSPCA1 in the early E2P state | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | Deposit date: | 2023-03-31 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWW
| hSPCA1 in the CaE1P-ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | Deposit date: | 2023-03-31 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWU
| hSPCA1 in the E2~P state | Descriptor: | Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | Deposit date: | 2023-03-31 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWS
| hSPCA1 in the CaE2P state | Descriptor: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | Deposit date: | 2023-03-31 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWR
| hSPCA1 in the CaE1-ATP state | Descriptor: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, ... | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | Deposit date: | 2023-03-31 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWP
| hSPCA1 in the CaE1 state | Descriptor: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1 | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | Deposit date: | 2023-03-30 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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