2HR3
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![BU of 2hr3 by Molmil](/molmil-images/mine/2hr3) | Crystal structure of putative transcriptional regulator protein from Pseudomonas aeruginosa PA01 at 2.4 A resolution | Descriptor: | Probable transcriptional regulator | Authors: | Kirillova, O, Chruszcz, M, Evdokimova, E, Kudritska, M, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-07-19 | Release date: | 2006-09-19 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of putative transcriptional regulator protein from Pseudomonas aeruginosa PA01 at 2.4 A resolution To be Published
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2I10
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![BU of 2i10 by Molmil](/molmil-images/mine/2i10) | Putative TetR transcriptional regulator from Rhodococcus sp. RHA1 | Descriptor: | P-NITROPHENOL, Putative TetR transcriptional regulator, TRIETHYLENE GLYCOL | Authors: | Osipiuk, J, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-08-11 | Release date: | 2006-09-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | X-ray crystal structure of putative TetR transcriptional regulator from Rhodococcus sp. RHA1. To be Published
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2FIY
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![BU of 2fiy by Molmil](/molmil-images/mine/2fiy) | The crystal structure of the FdhE protein from Pseudomonas aeruginosa | Descriptor: | FE (III) ION, Protein fdhE homolog | Authors: | Zhang, R, Evdokimova, E, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-30 | Release date: | 2006-02-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of the FdhE protein from Pseudomonas aeruginosa PAO1 To be Published
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2FKB
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![BU of 2fkb by Molmil](/molmil-images/mine/2fkb) | Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12 | Descriptor: | ACETATE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-01-04 | Release date: | 2006-02-21 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12 To be Published
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2FBI
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![BU of 2fbi by Molmil](/molmil-images/mine/2fbi) | The crystal structure of transcriptional regulator PA4135 | Descriptor: | probable transcriptional regulator | Authors: | Lunin, V.V, Evdokimova, E, Kudritska, M, Cuff, M.E, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of transcriptional regulator PA4135 To be Published
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2FBH
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![BU of 2fbh by Molmil](/molmil-images/mine/2fbh) | The crystal structure of transcriptional regulator PA3341 | Descriptor: | MERCURY (II) ION, SULFATE ION, ZINC ION, ... | Authors: | Lunin, V.V, Evdokimova, E, Kudritska, M, Osipiuk, J, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of transcriptional regulator PA3341 To be Published
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2HKU
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![BU of 2hku by Molmil](/molmil-images/mine/2hku) | Structural Genomics, the crystal structure of a putative transcriptional regulator from Rhodococcus sp. RHA1 | Descriptor: | 1,2-ETHANEDIOL, A putative transcriptional regulator, TETRAETHYLENE GLYCOL | Authors: | Tan, K, Evdokimova, E, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-07-05 | Release date: | 2006-08-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of a transcriptional regulator from Rhodococcus sp. RHA1 To be Published
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2FEF
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![BU of 2fef by Molmil](/molmil-images/mine/2fef) | The Crystal Structure of Protein PA2201 from Pseudomonas aeruginosa | Descriptor: | 1,2-ETHANEDIOL, hypothetical protein PA2201 | Authors: | Cymborowski, M.T, Chruszcz, M, Wang, S, Shumilin, I, Kudritska, M, Evdokimova, E, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-15 | Release date: | 2006-01-31 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Crystal Structure of Protein PA2201 from Pseudomonas aeruginosa To be Published
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2GFN
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![BU of 2gfn by Molmil](/molmil-images/mine/2gfn) | Crystal structure of HTH-type transcriptional regulator pksA related protein from Rhodococcus sp. RHA1 | Descriptor: | CHLORIDE ION, HTH-type transcriptional regulator pksA related protein | Authors: | Nocek, B, Evdokimova, E, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-03-22 | Release date: | 2006-04-25 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of HTH-type transcriptional regulator pksA related protein from Rhodococcus sp. RHA1 To be Published
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2G9I
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![BU of 2g9i by Molmil](/molmil-images/mine/2g9i) | Crystal structure of homolog of F420-0:gamma-Glutamyl Ligase from Archaeoglobus fulgidus Reveals a Novel Fold. | Descriptor: | F420-0:gamma-glutamyl ligase | Authors: | Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-03-06 | Release date: | 2006-04-04 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of an amide bond forming F(420):gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases. J.Mol.Biol., 372, 2007
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2G39
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![BU of 2g39 by Molmil](/molmil-images/mine/2g39) | Crystal structure of coenzyme A transferase from Pseudomonas aeruginosa | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Acetyl-CoA hydrolase | Authors: | Chang, C, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-02-17 | Release date: | 2006-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of coenzyme A transferase from Pseudomonas aeruginosa To be Published
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2FTP
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![BU of 2ftp by Molmil](/molmil-images/mine/2ftp) | Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa | Descriptor: | GLYCEROL, SODIUM ION, hydroxymethylglutaryl-CoA lyase | Authors: | Xiao, T, Evdokimova, E, Liu, Y, Kudritska, M, Savchenko, A, Pai, E.F, Edwards, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-01-24 | Release date: | 2006-03-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of hydroxymethylglutaryl-CoA lyase from Pseudomonas aeruginosa To be Published
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2G3B
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![BU of 2g3b by Molmil](/molmil-images/mine/2g3b) | Crystal structure of putative TetR-family transcriptional regulator from Rhodococcus sp. | Descriptor: | GLYCEROL, putative TetR-family transcriptional regulator | Authors: | Chruszcz, M, Evdokimova, E, Cymborowski, M, Kagan, O, Wang, S, Koclega, K.D, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-02-17 | Release date: | 2006-03-14 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of putative TetR-family transcriptional regulator from Rhodococcus sp. To be Published
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2GAX
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![BU of 2gax by Molmil](/molmil-images/mine/2gax) | Structure of Protein of Unknown Function Atu0240 from Agrobacteriium tumerfaciencs str. C58 | Descriptor: | PHOSPHATE ION, hypothetical protein Atu0240 | Authors: | Binkowski, T.A, Evdokimova, E, Kudritska, M, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-03-09 | Release date: | 2006-05-09 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Hypothetical protein Atu0240 from Agrobacteriium tumerfaciencs str. C58 TO BE PUBLISHED
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3VDH
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![BU of 3vdh by Molmil](/molmil-images/mine/3vdh) | Crystal structure of PbGH5A, a glycoside hydrolase family 5 enzyme from Prevotella bryantii B14 | Descriptor: | B-1,4-endoglucanase, CHLORIDE ION | Authors: | Stogios, P.J, Evdokimova, E, Egorova, O, Yim, V, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-01-05 | Release date: | 2012-01-18 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structure-Function Analysis of a Mixed-linkage beta-Glucanase/Xyloglucanase from the Key Ruminal Bacteroidetes Prevotella bryantii B14. J.Biol.Chem., 291, 2016
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3VCX
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![BU of 3vcx by Molmil](/molmil-images/mine/3vcx) | Crystal structure of a putative glyoxalase/bleomycin resistance protein from Rhodopseudomonas palustris CGA009 | Descriptor: | Glyoxalase/Bleomycin resistance protein/dioxygenase domain, TETRAETHYLENE GLYCOL | Authors: | Stogios, P.J, Chang, C, Evdokimova, E, Egorova, O, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-01-04 | Release date: | 2012-01-18 | Last modified: | 2012-01-25 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Crystal structure of a putative glyoxalase/bleomycin resistance protein from Rhodopseudomonas palustris CGA009 To be Published
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5NMI
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![BU of 5nmi by Molmil](/molmil-images/mine/5nmi) | Cytochrome bc1 bound to the inhibitor MJM170 | Descriptor: | (4aS)-2-methyl-3-(4-phenoxyphenyl)-5,6,7,8-tetrahydroquinolin-4(4aH)-one, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ARG-ASN-TRP-VAL-PRO-THR-ALA-GLN-LEU-TRP-GLY-ALA-VAL-GLY-ALA-VAL-GLY-LEU-VAL-SER-ALA-THR, ... | Authors: | Capper, N.J, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2017-04-05 | Release date: | 2017-06-14 | Last modified: | 2018-12-19 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. Sci Rep, 6, 2016
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8HG6
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![BU of 8hg6 by Molmil](/molmil-images/mine/8hg6) | Cryo-EM structure of the prasinophyte-specific light-harvesting complex (Lhcp)from Ostreococcus tauri | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-1-[(1~{S},4~{S})-2,2-dimethyl-6-methylidene-1,4-bis(oxidanyl)cyclohexyl]-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-2-one, ... | Authors: | Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z. | Deposit date: | 2022-11-13 | Release date: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers. Elife, 12, 2023
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8HG5
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![BU of 8hg5 by Molmil](/molmil-images/mine/8hg5) | Cryo-EM structure of the prasinophyte-specific light-harvesting complex (Lhcp)from Ostreococcus tauri | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-1-[(1~{S},4~{S})-2,2-dimethyl-6-methylidene-1,4-bis(oxidanyl)cyclohexyl]-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-2-one, ... | Authors: | Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z. | Deposit date: | 2022-11-13 | Release date: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers. Elife, 12, 2023
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8HG3
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![BU of 8hg3 by Molmil](/molmil-images/mine/8hg3) | Cryo-EM structure of the Lhcp complex from Ostreococcus tauri | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-1-[(1~{S},4~{S})-2,2-dimethyl-6-methylidene-1,4-bis(oxidanyl)cyclohexyl]-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-2-one, ... | Authors: | Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z. | Deposit date: | 2022-11-13 | Release date: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers. Elife, 12, 2023
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8H2U
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![BU of 8h2u by Molmil](/molmil-images/mine/8h2u) | X-ray Structure of photosystem I-LHCI super complex from Chlamydomonas reinhardtii. | Descriptor: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Tanaka, H, Kubota-Kawai, H, Misumi, Y, Kurisu, G. | Deposit date: | 2022-10-07 | Release date: | 2023-06-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Three structures of PSI-LHCI from Chlamydomonas reinhardtii suggest a resting state re-activated by ferredoxin. Biochim Biophys Acta Bioenerg, 1864, 2023
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6WI7
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![BU of 6wi7 by Molmil](/molmil-images/mine/6wi7) | RING1B-BMI1 fusion in closed conformation | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1 chimera, ... | Authors: | Cho, H.J, Cierpicki, T. | Deposit date: | 2020-04-08 | Release date: | 2021-04-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain. Nat.Chem.Biol., 17, 2021
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6WI8
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![BU of 6wi8 by Molmil](/molmil-images/mine/6wi8) | |
6WZW
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![BU of 6wzw by Molmil](/molmil-images/mine/6wzw) | Ash1L SET domain in complex with AS-85 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Histone-lysine N-methyltransferase ASH1L, N-{[3-(3-carbamothioylphenyl)-1-{1-[(trifluoromethyl)sulfonyl]piperidin-4-yl}-1H-indol-6-yl]methyl}azetidine-3-carboxamide, ... | Authors: | Li, H, Deng, J, Cierpicki, T, Grembecka, J. | Deposit date: | 2020-05-14 | Release date: | 2021-04-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun, 12, 2021
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6X0P
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![BU of 6x0p by Molmil](/molmil-images/mine/6x0p) | Ash1L SET domain Q2265A mutant in complex with AS-5 | Descriptor: | 3-[6-(aminomethyl)-1-(2-hydroxyethyl)-1H-indol-3-yl]benzene-1-carbothioamide, Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ... | Authors: | Rogawski, D.S, Li, H, Borkin, D, Cierpicki, T, Grembecka, J. | Deposit date: | 2020-05-17 | Release date: | 2021-04-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun, 12, 2021
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