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4RQQ
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BU of 4rqq by Molmil
Crystal structure of human Fab PGDM1400, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: Human anti-HIV-1 antibody PGDM1400 heavy chain, Human anti-HIV-1 antibody PGDM1400 light chain
Authors:Julien, J.-P, Wilson, I.A.
Deposit date:2014-11-04
Release date:2014-11-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RNR
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BU of 4rnr by Molmil
Crystal structure of broadly neutralizing anti-HIV antibody PGT130
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain
Authors:Kong, L, Wilson, I.A.
Deposit date:2014-10-24
Release date:2014-11-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
J.Virol., 89, 2015
4RQS
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BU of 4rqs by Molmil
Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab
Descriptor: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kong, L, Wilson, I.A, Kwong, P.D.
Deposit date:2014-11-05
Release date:2014-12-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.493 Å)
Cite:Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Proteins, 83, 2015
1Y18
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BU of 1y18 by Molmil
Fab fragment of catalytic elimination antibody 34E4 E(H50)D mutant in complex with hapten
Descriptor: 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic antibody 34E4 heavy chain, ...
Authors:Debler, E.W, Ito, S, Heine, A, Wilson, I.A.
Deposit date:2004-11-17
Release date:2005-04-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Proc.Natl.Acad.Sci.USA, 102, 2005
2AFE
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BU of 2afe by Molmil
Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence
Descriptor: protein Asl1650
Authors:Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2005-07-25
Release date:2005-08-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence
Protein Sci., 15, 2006
1XZ0
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BU of 1xz0 by Molmil
Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(HYDROXY-HEXADECANOYL-AMINO)-2-{[(4S)-2-(2-HYDROXY-PHENYL)-4,5-DIHYDRO-OXAZOLE-4-CARBONYL]-AMINO}-HEXANOIC ACID 2-[(3S)-1-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-2-OXO-AZEPAN-3-YLCARBAMOYL]-(1S)-1-METHYL-ETHYL ESTER, Beta-2-microglobulin, ...
Authors:Zajonc, D.M, Crispin, M.D, Bowden, T.A, Young, D.C, Cheng, T.Y, Hu, J, Costello, C.E, Miller, M.J, Moody, D.B, Wilson, I.A.
Deposit date:2004-11-11
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Mechanism of Lipopeptide Presentation by CD1a.
Immunity, 22, 2005
1Z5L
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BU of 1z5l by Molmil
Structure of a highly potent short-chain galactosyl ceramide agonist bound to CD1D
Descriptor: (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zajonc, D.M, Cantu, C, Mattner, J, Zhou, D, Savage, P.B, Bendelac, A, Wilson, I.A, Teyton, L.
Deposit date:2005-03-18
Release date:2005-07-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor.
Nat.Immunol., 6, 2005
2AFD
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BU of 2afd by Molmil
Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence
Descriptor: protein Asl1650
Authors:Johnson, M.A, Peti, W, Herrmann, T, Wilson, I.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2005-07-25
Release date:2005-08-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence
Protein Sci., 15, 2006
1ZXT
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BU of 1zxt by Molmil
Crystal Structure of A Viral Chemokine
Descriptor: functional macrophage inflammatory protein 1-alpha homolog
Authors:Luz, J.G, Yu, M, Su, Y, Wu, Z, Zhou, Z, Sun, R, Wilson, I.A.
Deposit date:2005-06-08
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
J.Mol.Biol., 352, 2005
1Y0L
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BU of 1y0l by Molmil
Catalytic elimination antibody 34E4 in complex with hapten
Descriptor: 2-AMINO-5,6-DIMETHYL-BENZIMIDAZOLE-1-PENTANOIC ACID, CHLORIDE ION, Catalytic Antibody Fab 34E4 Heavy chain, ...
Authors:Debler, E.W, Ito, S, Heine, A, Wilson, I.A.
Deposit date:2004-11-15
Release date:2005-04-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural origins of efficient proton abstraction from carbon by a catalytic antibody
Proc.Natl.Acad.Sci.USA, 102, 2005
2AJV
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BU of 2ajv by Molmil
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Cocaine
Descriptor: Antibody 7A1 Fab', COCAINE
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AJS
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BU of 2ajs by Molmil
Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Antibody 7A1 FAB', GLYCEROL, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AJZ
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BU of 2ajz by Molmil
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester
Descriptor: 3-HYDROXY-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER, Antibody 7A1 Fab'
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AJY
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BU of 2ajy by Molmil
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester and benzoic acid
Descriptor: 3-HYDROXY-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER, Antibody 7A1 Fab', BENZOIC ACID, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AK1
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BU of 2ak1 by Molmil
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with benzoic acid
Descriptor: Antibody 7A1 Fab', BENZOIC ACID, ZINC ION
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2AJX
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BU of 2ajx by Molmil
Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Transition State Analog
Descriptor: 3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER, Antibody 7A1 Fab'
Authors:Zhu, X, Wilson, I.A.
Deposit date:2005-08-02
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
2DBL
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BU of 2dbl by Molmil
MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
Descriptor: 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
Authors:Arevalo, J.H, Wilson, I.A.
Deposit date:1994-02-08
Release date:1994-03-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
4MHI
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BU of 4mhi by Molmil
Crystal structure of a H5N1 influenza virus hemagglutinin from A/goose/Guangdong/1/96
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
4M6K
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BU of 4m6k by Molmil
Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and folate
Descriptor: Dihydrofolate reductase, FOLIC ACID, GLYCEROL, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2013-08-09
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.396 Å)
Cite:Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
4MAS
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BU of 4mas by Molmil
High Resolution Structure of Wild Type Human Transthyretin in Complex with 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol
Descriptor: 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL, Transthyretin
Authors:Connelly, S, Bradbury, N.C, Wilson, I.A.
Deposit date:2013-08-16
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:High Resolution Structure of Wild Type Human Transthyretin in Complex with 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol
To be Published
4MHH
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BU of 4mhh by Molmil
Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/Viet Nam/1203/2004 (H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H5M9 antibody, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.564 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
4M4Y
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BU of 4m4y by Molmil
Crystal structure of a 2009 H1N1 influenza virus hemagglutinin with a stabilization mutation HA2 E47G
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-07
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site.
J.Virol., 87, 2013
4L1T
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BU of 4l1t by Molmil
Transthyretin in complex with (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzoic acid
Descriptor: 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn.
Biopolymers, 101, 2014
4LG2
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BU of 4lg2 by Molmil
Crystal structure of Reston Ebola virus VP35 RNA binding domain bound to 12-bp dsRNA
Descriptor: Polymerase cofactor, dsRNA
Authors:Bale, S, Julien, J.-P, Bornholdt, Z.A, Krois, A.S, Wilson, I.A, Saphire, E.O.
Deposit date:2013-06-27
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism.
J.Virol., 87, 2013
4L1S
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BU of 4l1s by Molmil
Covalent modification of transthyretin K15 by yielding the fluorescent conjugate (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzamide
Descriptor: S-(4-fluorophenyl) 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzenecarbothioate, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn.
Biopolymers, 101, 2014

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