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4H9R
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BU of 4h9r by Molmil
Complex structure 5 of DAXX(E225A)/H3.3(sub5,G90A)/H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4H9O
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BU of 4h9o by Molmil
Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
1FJ5
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BU of 1fj5 by Molmil
TAMOXIFEN-DNA ADDUCT
Descriptor: (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINIUM, DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3')
Authors:Shimotakahara, S, Gorin, A, Kolbanovskiy, A, Kettani, A, Hingerty, B.E, Amin, S, Broyde, S, Geacintov, N, Patel, D.J.
Deposit date:2000-08-07
Release date:2000-09-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Accomodation of S-cis-tamoxifen-N(2)-guanine adduct within a bent and widened DNA minor groove.
J.Mol.Biol., 302, 2000
4JOL
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BU of 4jol by Molmil
Complex structure of AML1-ETO NHR2 domain with HEB fragment
Descriptor: Protein CBFA2T1, Transcription factor 12
Authors:Wang, Z, Patel, D.J.
Deposit date:2013-03-18
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Nature, 500, 2013
4JVH
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BU of 4jvh by Molmil
Structure of the star domain of quaking protein in complex with RNA
Descriptor: Protein quaking, RNA (5'-R(*UP*UP*CP*AP*CP*UP*AP*AP*CP*AP*A)-3'), SULFATE ION
Authors:Teplova, M, Hafner, M, Teplov, D, Essig, K, Tuschl, T, Patel, D.J.
Deposit date:2013-03-25
Release date:2013-05-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Genes Dev., 27, 2013
4JVY
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BU of 4jvy by Molmil
Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA
Descriptor: Female germline-specific tumor suppressor gld-1, RNA (5'-R(P*CP*UP*AP*AP*CP*AP*A)-3')
Authors:Teplova, M, Hafner, M, Teplov, D, Essig, K, Tuschl, T, Patel, D.J.
Deposit date:2013-03-26
Release date:2013-05-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.853 Å)
Cite:Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.
Genes Dev., 27, 2013
4IUT
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BU of 4iut by Molmil
crystal structure of SHH1 SAWADEE domain in complex with H3K9me2 peptide
Descriptor: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
Authors:Du, J, Patel, D.J.
Deposit date:2013-01-21
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IUV
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BU of 4iuv by Molmil
crystal structure of SHH1 SAWADEE domain in complex with H3K4me1K9me1 peptide
Descriptor: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
Authors:Du, J, Patel, D.J.
Deposit date:2013-01-21
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IX7
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BU of 4ix7 by Molmil
Crystal Structure of the insv-BEN domain complexed to its DNA target site
Descriptor: 5'-D(*GP*TP*TP*CP*CP*AP*AP*TP*TP*GP*GP*AP*A)-3', RE55538p
Authors:Ren, A, Serganov, A, Patel, D.J.
Deposit date:2013-01-24
Release date:2013-03-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.581 Å)
Cite:The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors.
Genes Dev., 27, 2013
4H9N
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BU of 4h9n by Molmil
Complex structure 1 of DAXX/H3.3(sub5)/H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
4H9S
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BU of 4h9s by Molmil
Complex structure 6 of DAXX/H3.3(sub7)/H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
1G70
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BU of 1g70 by Molmil
COMPLEX OF HIV-1 RRE-IIB RNA WITH RSG-1.2 PEPTIDE
Descriptor: HIV-1 RRE-IIB 32 NUCLEOTIDE RNA, RSG-1.2 PEPTIDE
Authors:Gosser, Y, Hermann, T, Majumdar, A, Hu, W, Frederick, R, Jiang, F, Xu, W, Patel, D.J.
Deposit date:2000-11-08
Release date:2001-02-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Peptide-triggered conformational switch in HIV-1 RRE RNA complexes.
Nat.Struct.Biol., 8, 2001
4H9P
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BU of 4h9p by Molmil
Complex structure 3 of DAXX/H3.3(sub5,G90A)/H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J.
Deposit date:2012-09-24
Release date:2012-10-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
1I34
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BU of 1i34 by Molmil
SOLUTION DNA QUADRUPLEX WITH DOUBLE CHAIN REVERSAL LOOP AND TWO DIAGONAL LOOPS CONNECTING GGGG TETRADS FLANKED BY G-(T-T) TRIAD AND T-T-T TRIPLE
Descriptor: 5'-D(*GP*GP*TP*TP*TP*TP*GP*GP*CP*AP*GP*GP*GP*TP*TP*TP*TP*GP*GP*T)-3'
Authors:Kuryavyi, V, Majumdar, A, Shallop, A, Chernichenko, N, Skripkin, E, Jones, R, Patel, D.J.
Deposit date:2001-02-12
Release date:2001-06-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple.
J.Mol.Biol., 310, 2001
4K8V
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BU of 4k8v by Molmil
Structure of cyclic GMP-AMP Synthase (cGAS)
Descriptor: Cyclic GMP-AMP synthase, ZINC ION
Authors:Gao, P, Wu, Y, Patel, D.J.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
4K80
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BU of 4k80 by Molmil
Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 2:0 ceramide-1-phosphate (2:0-C1P)
Descriptor: (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1
Authors:Simanshu, D.K, Brown, R.E, Patel, D.J.
Deposit date:2013-04-17
Release date:2013-07-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
1EXY
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BU of 1exy by Molmil
SOLUTION STRUCTURE OF HTLV-1 PEPTIDE BOUND TO ITS RNA APTAMER TARGET
Descriptor: HTLV-1 REX PEPTIDE, RNA APTAMER, 33-MER
Authors:Jiang, F, Gorin, A, Hu, W, Majumdar, A, Baskerville, S, Xu, W, Ellington, A, Patel, D.J.
Deposit date:2000-05-05
Release date:2000-05-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples.
Structure Fold.Des., 7, 1999
4KBR
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BU of 4kbr by Molmil
Crystal structure of mouse Ceramide-1-phosphate transfer protein (apo-form)
Descriptor: Glycolipid transfer protein domain-containing protein 1, PHOSPHATE ION
Authors:Simanshu, D.K, Brown, R.E, Patel, D.J.
Deposit date:2013-04-23
Release date:2013-07-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4K84
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BU of 4k84 by Molmil
Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 16:0 ceramide-1-phosphate (16:0-C1P)
Descriptor: (2S,3R,4E)-2-(hexadecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1
Authors:Simanshu, D.K, Brown, R.E, Patel, D.J.
Deposit date:2013-04-17
Release date:2013-07-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4K9A
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BU of 4k9a by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pG(2 ,5 )pA
Descriptor: ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ...
Authors:Gao, P, Wu, Y, Patel, D.J.
Deposit date:2013-04-19
Release date:2013-05-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.264 Å)
Cite:Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
3QZT
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BU of 3qzt by Molmil
Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form II
Descriptor: GLYCEROL, Histone H4, Nucleosome-remodeling factor subunit BPTF
Authors:Li, H, Ruthenburg, A.J, Patel, D.J.
Deposit date:2011-03-07
Release date:2011-06-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
3QZS
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BU of 3qzs by Molmil
Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form I
Descriptor: Histone H4, Nucleosome-remodeling factor subunit BPTF
Authors:Li, H, Ruthenburg, A.J, Patel, D.J.
Deposit date:2011-03-07
Release date:2011-06-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
3RB3
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BU of 3rb3 by Molmil
Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 1-methylguanine (m1g) lesion
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Rechkoblit, O, Patel, D.J.
Deposit date:2011-03-28
Release date:2011-06-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3RBD
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BU of 3rbd by Molmil
Dpo4 extension ternary complex with 3'-terminal primer C base opposite the 3-methylcytosine (m3c) lesion
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Rechkoblit, O, Patel, D.J.
Deposit date:2011-03-29
Release date:2011-06-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3QZV
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BU of 3qzv by Molmil
Crystal Structure of BPTF PHD-linker-bromo in complex with histone H4K12ac peptide
Descriptor: Histone H4, Nucleosome-remodeling factor subunit BPTF, ZINC ION
Authors:Li, H, Ruthenburg, A.J, Patel, D.J.
Deposit date:2011-03-07
Release date:2011-06-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011

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