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6EDC
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BU of 6edc by Molmil
hcGAS-16bp dsDNA complex
Descriptor: Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*T)-3'), ...
Authors:Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J.
Deposit date:2018-08-09
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
7JW2
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BU of 7jw2 by Molmil
Crystal structure of Aedes aegypti Nibbler EXO domain
Descriptor: Exonuclease mut-7 homolog
Authors:Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J.
Deposit date:2020-08-24
Release date:2021-01-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Proc.Natl.Acad.Sci.USA, 117, 2020
6D8P
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BU of 6d8p by Molmil
Ternary RsAgo Complex Containing Guide RNA Paired with Target DNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CACODYLATE ION, ...
Authors:Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J.
Deposit date:2018-04-26
Release date:2018-07-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
6D9L
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BU of 6d9l by Molmil
Ternary RsAgo Complex with Guide RNA and Target DNA Containing G-A Non-canonical Pair
Descriptor: DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*AP*GP*CP*AP*GP*TP*AP*AP*C)-3'), MAGNESIUM ION, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*GP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), ...
Authors:Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J.
Deposit date:2018-04-30
Release date:2018-07-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
7JW6
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BU of 7jw6 by Molmil
Crystal structure of Drosophila Nibbler EXO domain
Descriptor: Exonuclease mut-7 homolog
Authors:Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J.
Deposit date:2020-08-24
Release date:2021-01-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Proc.Natl.Acad.Sci.USA, 117, 2020
7K3J
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BU of 7k3j by Molmil
Crystal structure of dLC8 in complex with Panoramix TQT+TQ peptide
Descriptor: Dynein light chain 1, cytoplasmic, Protein panoramix, ...
Authors:Wang, J, Patel, D.J.
Deposit date:2020-09-11
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
7K3K
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BU of 7k3k by Molmil
Crystal structure of dLC8 in complex with Panoramix TQT peptide
Descriptor: Dynein light chain 1, cytoplasmic, Protein panoramix
Authors:Wang, J, Patel, D.J.
Deposit date:2020-09-11
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.415 Å)
Cite:Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev., 35, 2021
7L9P
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BU of 7l9p by Molmil
Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pachytene checkpoint protein 2 homolog, ...
Authors:Xie, W, Patel, D.J.
Deposit date:2021-01-04
Release date:2021-03-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LHL
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BU of 7lhl by Molmil
cryo-EM structure of Mycobacterium smegmatis Lhr helicase C-terminal domain
Descriptor: ATP-dependent DNA helicase
Authors:Wang, J, Warren, G.M, Shuman, S, Patel, D.J.
Deposit date:2021-01-25
Release date:2021-04-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Oligomeric quaternary structure of Escherichia coli and Mycobacterium smegmatis Lhr helicases is nucleated by a novel C-terminal domain composed of five winged-helix modules.
Nucleic Acids Res., 49, 2021
143D
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BU of 143d by Molmil
SOLUTION STRUCTURE OF THE HUMAN TELOMERIC REPEAT D(AG3[T2AG3]3) OF THE G-QUADRUPLEX
Descriptor: DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3')
Authors:Wang, Y, Patel, D.J.
Deposit date:1993-10-08
Release date:1994-04-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex.
Structure, 1, 1993
107D
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BU of 107d by Molmil
SOLUTION STRUCTURE OF THE COVALENT DUOCARMYCIN A-DNA DUPLEX COMPLEX
Descriptor: 4-HYDROXY-2,8-DIMETHYL-1-OXO-6-(4,5,6-TRIMETHOXY-1H-INDOLE-2-CARBONYL)-1,2,3,6,7,8-HEXAHYDRO-3,6-DIAZA-AS-INDACENE-2-CARBOXYLIC ACID METHYL ESTER, DNA (5'-D(*CP*CP*TP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*AP*GP*G)-3')
Authors:Lin, C.H, Patel, D.J.
Deposit date:1995-01-17
Release date:1995-05-08
Last modified:2024-03-13
Method:SOLUTION NMR
Cite:Solution structure of the covalent duocarmycin A-DNA duplex complex.
J.Mol.Biol., 248, 1995
1AFF
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BU of 1aff by Molmil
DNA QUADRUPLEX CONTAINING GGGG TETRADS AND (T.A).A TRIADS, NMR, 8 STRUCTURES
Descriptor: QUADRUPLEX DNA (5'-D(TP*AP*GP*G)-3')
Authors:Kettani, A, Bouaziz, S, Wang, W, Jones, R.A, Patel, D.J.
Deposit date:1997-03-06
Release date:1997-08-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Bombyx mori single repeat telomeric DNA sequence forms a G-quadruplex capped by base triads.
Nat.Struct.Biol., 4, 1997
193D
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BU of 193d by Molmil
SOLUTION STRUCTURE OF A QUINOMYCIN BISINTERCALATOR-DNA COMPLEX
Descriptor: 3-HYDROXYQUINALDIC ACID, DNA (5'-D(*AP*CP*AP*CP*GP*TP*GP*T)-3'), QUINOMYCIN
Authors:Chen, H, Patel, D.J.
Deposit date:1994-09-30
Release date:1995-02-27
Last modified:2017-11-01
Method:SOLUTION NMR
Cite:Solution Structure of a Quinomycin Bisintercalator-DNA Complex.
J.Mol.Biol., 246, 1995
179D
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BU of 179d by Molmil
SOLUTION STRUCTURE OF THE D(T-C-G-A) DUPLEX AT ACIDIC PH: A PARALLEL-STRANDED HELIX CONTAINING C+.C, G.G AND A.A PAIRS
Descriptor: DNA (5'-D(*TP*CP*GP*A)-3')
Authors:Wang, Y, Patel, D.J.
Deposit date:1994-06-15
Release date:1994-07-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the d(T-C-G-A) duplex at acidic pH. A parallel-stranded helix containing C+ .C, G.G and A.A pairs.
J.Mol.Biol., 242, 1994
186D
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BU of 186d by Molmil
SOLUTION STRUCTURE OF THE TETRAHYMENA TELOMERIC REPEAT D(T2G4)4 G-TETRAPLEX
Descriptor: DNA (5'-D(*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3')
Authors:Wang, Y, Patel, D.J.
Deposit date:1994-08-22
Release date:1994-11-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex.
Structure, 2, 1994
1A4T
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BU of 1a4t by Molmil
SOLUTION STRUCTURE OF PHAGE P22 N PEPTIDE-BOX B RNA COMPLEX, NMR, 20 STRUCTURES
Descriptor: 20-MER BASIC PEPTIDE, BOXB RNA
Authors:Cai, Z, Gorin, A.A, Frederick, R, Ye, X, Hu, W, Majumdar, A, Kettani, A, Patel, D.J.
Deposit date:1998-02-04
Release date:1998-04-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of P22 transcriptional antitermination N peptide-boxB RNA complex.
Nat.Struct.Biol., 5, 1998
1A6H
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BU of 1a6h by Molmil
DNA QUADRUPLEX CONTAINING GCGC TETRAD, NMR, 4 STRUCTURES
Descriptor: DNA (5'-D(GP*CP*GP*GP*TP*TP*TP*GP*CP*GP*G)-3')
Authors:Kettani, A, Kumar, R.A, Patel, D.J.
Deposit date:1998-02-25
Release date:1998-06-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a DNA quadruplex containing the fragile X syndrome triplet repeat.
J.Mol.Biol., 254, 1995
1AM0
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BU of 1am0 by Molmil
AMP RNA APTAMER COMPLEX, NMR, 8 STRUCTURES
Descriptor: ADENOSINE MONOPHOSPHATE, RNA APTAMER
Authors:Jiang, F, Kumar, R.A, Jones, R.A, Patel, D.J.
Deposit date:1997-06-19
Release date:1997-07-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Basis of RNA Folding and Recognition in an AMP-RNA Aptamer Complex
Nature, 382, 1996
199D
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BU of 199d by Molmil
Solution structure of the monoalkylated mitomycin c-DNA complex
Descriptor: CARBAMIC ACID 2,6-DIAMINO-5-METHYL-4,7-DIOXO-2,3,4,7-TETRAHYDRO-1H-3A-AZA-CYCLOPENTA[A]INDEN-8-YLMETHYL ESTER, DNA (5'-D(*(DI)P*CP*AP*CP*GP*TP*CP*(DI)P*T)-3'), DNA (5'-D(*AP*CP*GP*AP*CP*GP*TP*GP*C)-3')
Authors:Sastry, M, Fiala, R, Lipman, R, Tomasz, M, Patel, D.J.
Deposit date:1994-12-01
Release date:1995-02-07
Last modified:2024-03-13
Method:SOLUTION NMR
Cite:Solution structure of the monoalkylated mitomycin C-DNA complex.
J.Mol.Biol., 247, 1995
1A8N
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BU of 1a8n by Molmil
SOLUTION STRUCTURE OF A NA+ CATION STABILIZED DNA QUADRUPLEX CONTAINING G.G.G.G AND G.C.G.C TETRADS FORMED BY G-G-G-C REPEATS OBSERVED IN AAV AND HUMAN CHROMOSOME 19, NMR, 8 STRUCTURES
Descriptor: DNA QUADRUPLEX CONTAINING G.G.G.G AND G.C.G.C TETRADS
Authors:Kettani, A, Bouaziz, S, Gorin, A, Zhao, H, Jones, R, Patel, D.J.
Deposit date:1998-03-27
Release date:1998-10-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a Na cation stabilized DNA quadruplex containing G.G.G.G and G.C.G.C tetrads formed by G-G-G-C repeats observed in adeno-associated viral DNA.
J.Mol.Biol., 282, 1998
1AX7
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BU of 1ax7 by Molmil
SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT POSITIONED AT A TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES
Descriptor: 2-AMINOFLUORENE, DNA DUPLEX D(AAC-[AF]G-CTACCATCC)D(GGATGGTAG)
Authors:Mao, B, Gu, Z, Gorin, A.A, Hingerty, B.E, Broyde, S, Patel, D.J.
Deposit date:1997-10-30
Release date:1998-07-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the aminofluorene-stacked conformer of the syn [AF]-C8-dG adduct positioned at a template-primer junction.
Biochemistry, 36, 1997
1AXO
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BU of 1axo by Molmil
STRUCTURAL ALIGNMENT OF THE (+)-TRANS-ANTI-[BP]DG ADDUCT POSITIONED OPPOSITE DC AT A DNA TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES
Descriptor: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA DUPLEX D(AAC-[BP]G-CTACCATCC)D(GGATGGTAGC)
Authors:Feng, B, Gorin, A.A, Hingerty, B.E, Geacintov, N.E, Broyde, S, Patel, D.J.
Deposit date:1997-10-16
Release date:1998-07-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction.
Biochemistry, 36, 1997
1A8W
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BU of 1a8w by Molmil
A K+ CATION-INDUCED CONFORMATIONAL SWITCH WITHIN A LOOP SPANNING SEGMENT OF A DNA QUADRUPLEX CONTAINING G-G-G-C REPEATS, NMR, 8 STRUCTURES
Descriptor: DNA QUADRUPLEX CONTAINING GGGG TETRADS AND GC WATSON-CRICK BASE PAIRS
Authors:Bouaziz, S, Kettani, A, Patel, D.J.
Deposit date:1998-03-28
Release date:1998-10-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A K cation-induced conformational switch within a loop spanning segment of a DNA quadruplex containing G-G-G-C repeats.
J.Mol.Biol., 282, 1998
177D
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BU of 177d by Molmil
SOLUTION STRUCTURE AND HYDRATION PATTERNS OF A PYRIMIDINE(DOT)PURINE(DOT)PYRIMIDINE DNA TRIPLEX CONTAINING A NOVEL T(DOT)CG TRIPLE
Descriptor: DNA (5'-D(*GP*AP*AP*CP*AP*GP*GP*TP*TP*TP*TP*T*CP*CP*TP*GP*TP*TP*CP*TP*TP*TP*TP*T*CP*TP*TP*TP*TP*CP*C)-3')
Authors:Radhakrishnan, I, Patel, D.J.
Deposit date:1994-05-24
Release date:1994-10-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and hydration patterns of a pyrimidine.purine.pyrimidine DNA triplex containing a novel T.CG base-triple.
J.Mol.Biol., 241, 1994
1AXU
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BU of 1axu by Molmil
SOLUTION NMR STRUCTURE OF THE [AP]DG ADDUCT OPPOSITE DA IN A DNA DUPLEX, NMR, 9 STRUCTURES
Descriptor: DNA DUPLEX D(CCATC-[AP]G-CTACC)D(GGTAGAGATGG), N-1-AMINOPYRENE
Authors:Gu, Z, Gorin, A.A, Krishnasami, R, Hingerty, B.E, Basu, A.K, Broyde, S, Patel, D.J.
Deposit date:1997-10-21
Release date:1998-07-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex.
Biochemistry, 38, 1999

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