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6XFM
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BU of 6xfm by Molmil
Molecular structure of the core of amyloid-like fibrils formed by residues 111-214 of FUS
Descriptor: RNA-binding protein FUS
Authors:Tycko, R, Lee, M, Ghosh, U, Thurber, K, Kato, M.
Deposit date:2020-06-15
Release date:2020-10-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS.
Nat Commun, 11, 2020
8EZD
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BU of 8ezd by Molmil
Brain-derived 42-residue amyloid-beta fibril type A
Descriptor: Beta-amyloid protein 42
Authors:Tycko, R, Lee, M, Yau, Y.-M, Louis, J.M.
Deposit date:2022-10-31
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structures of brain-derived 42-residue amyloid-beta fibril polymorphs with unusual molecular conformations and intermolecular interactions.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EZE
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BU of 8eze by Molmil
Brain-derived 42-residue amyloid-beta fibril type B
Descriptor: Beta-amyloid protein 42
Authors:Tycko, R, Lee, M, Yau, Y.-M, Louis, J.M.
Deposit date:2022-10-31
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structures of brain-derived 42-residue amyloid-beta fibril polymorphs with unusual molecular conformations and intermolecular interactions.
Proc.Natl.Acad.Sci.USA, 120, 2023
2LMP
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BU of 2lmp by Molmil
Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Positive Stagger
Descriptor: Beta-amyloid protein 40
Authors:Tycko, R, Paravastu, A.
Deposit date:2011-12-08
Release date:2011-12-28
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils
Proc.Natl.Acad.Sci.USA, 105, 2008
2LMN
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BU of 2lmn by Molmil
Structural Model for a 40-Residue Beta-Amyloid Fibril with Two-Fold Symmetry, Positive Stagger
Descriptor: Beta-amyloid protein 40
Authors:Tycko, R, Petkova, A.
Deposit date:2011-12-08
Release date:2011-12-28
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils.
Proc. Natl. Acad. Sci. U.S.A., 105, 2008
2LMO
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BU of 2lmo by Molmil
Structural Model for a 40-Residue Beta-Amyloid Fibril with Two-Fold Symmetry, Negative Stagger
Descriptor: Beta-amyloid protein 40
Authors:Tycko, R, Petkova, A.
Deposit date:2011-12-08
Release date:2011-12-28
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils.
Proc. Natl. Acad. Sci. U.S.A., 105, 2008
2LMQ
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BU of 2lmq by Molmil
Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Negative Stagger
Descriptor: Beta-amyloid protein 40
Authors:Tycko, R, Paravastu, A.
Deposit date:2011-12-09
Release date:2011-12-28
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils.
Proc. Natl. Acad. Sci. U.S.A., 105, 2008
5W3N
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BU of 5w3n by Molmil
Molecular structure of FUS low sequence complexity domain protein fibrils
Descriptor: RNA-binding protein FUS
Authors:Murray, D.T, Kato, M, Lin, Y, Thurber, K, Hung, I, McKnight, S, Tycko, R.
Deposit date:2017-06-08
Release date:2017-09-27
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains.
Cell, 171, 2017
6W0O
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BU of 6w0o by Molmil
Amyloid-beta(1-40) fibril derived from Alzheimer's disease cortical tissue
Descriptor: Amyloid-beta precursor protein
Authors:Ghosh, U, Thurber, K.R, Tycko, R.
Deposit date:2020-03-02
Release date:2021-01-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.77 Å), SOLID-STATE NMR
Cite:Molecular structure of a prevalent amyloid-beta fibril polymorph from Alzheimer's disease brain tissue.
Proc.Natl.Acad.Sci.USA, 118, 2021
5IRT
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BU of 5irt by Molmil
Dimerization interface of the noncrystalline HIV-1 capsid protein lattice from solid state NMR spectroscopy of tubular assemblies
Descriptor: Capsid protein p24
Authors:Bayro, M.J, Tycko, R.
Deposit date:2016-03-14
Release date:2016-06-22
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Structure of the Dimerization Interface in the Mature HIV-1 Capsid Protein Lattice from Solid State NMR of Tubular Assemblies.
J.Am.Chem.Soc., 138, 2016
3V19
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BU of 3v19 by Molmil
Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A.
Deposit date:2011-12-09
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
To be Published
3V1G
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BU of 3v1g by Molmil
Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A.
Deposit date:2011-12-09
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
To be Published
2LNQ
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BU of 2lnq by Molmil
40-residue D23N beta amyloid fibril
Descriptor: P3(40)
Authors:Qiang, W, Yau, W, Luo, Y, Mattson, M.P, Tycko, R.
Deposit date:2012-01-03
Release date:2012-02-08
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Antiparallel beta-sheet architecture in Iowa-mutant beta-amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 109, 2012
2N1E
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BU of 2n1e by Molmil
MAX1 peptide fibril
Descriptor: MAX1 peptide
Authors:Nagy-Smith, K, Moore, E, Schneider, J, Tycko, R.
Deposit date:2015-03-30
Release date:2015-07-29
Last modified:2024-10-30
Method:SOLID-STATE NMR
Cite:Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network.
Proc.Natl.Acad.Sci.USA, 112, 2015
2M4J
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BU of 2m4j by Molmil
40-residue beta-amyloid fibril derived from Alzheimer's disease brain
Descriptor: Amyloid beta A4 protein
Authors:Lu, J, Qiang, W, Meredith, S.C, Yau, W, Schweiters, C.D, Tycko, R.
Deposit date:2013-02-05
Release date:2013-09-25
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue.
Cell(Cambridge,Mass.), 154, 2013

227111

數據於2024-11-06公開中

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