2ROL
| Structural Basis of PxxDY motif recognition in SH3 binding | Descriptor: | 12-meric peptide from T-cell surface glycoprotein CD3 epsilon chain, Epidermal growth factor receptor kinase substrate 8-like protein 1 | Authors: | Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Paakkonen, K, Saksela, K, Permi, P. | Deposit date: | 2008-04-02 | Release date: | 2009-03-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of PxxDY motif recognition in SH3 binding J.Mol.Biol., 382, 2008
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5I22
| Amphiphysin SH3 in complex with Chikungunya virus nsP3 peptide | Descriptor: | CHIKV nsP3 peptide, Myc box-dependent-interacting protein 1 | Authors: | Tossavainen, H, Aitio, O, Hellman, M, Saksela, K, Permi, P. | Deposit date: | 2016-02-04 | Release date: | 2016-06-15 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural Basis of the High Affinity Interaction between the Alphavirus Nonstructural Protein-3 (nsP3) and the SH3 Domain of Amphiphysin-2. J.Biol.Chem., 291, 2016
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2K2M
| Structural Basis of PxxDY Motif Recognition in SH3 Binding | Descriptor: | Eps8-like protein 1 | Authors: | Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Saksela, K, Permi, P. | Deposit date: | 2008-04-02 | Release date: | 2009-02-17 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Structural basis of PxxDY motif recognition in SH3 binding. J.Mol.Biol., 382, 2008
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2LNH
| Enterohaemorrhagic E. coli (EHEC) exploits a tryptophan switch to hijack host F-actin assembly | Descriptor: | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, Neural Wiskott-Aldrich syndrome protein, Secreted effector protein EspF(U) | Authors: | Aitio, O, Hellman, M, Skehan, B, Kesti, T, Leong, J.M, Saksela, K, Permi, P. | Deposit date: | 2011-12-28 | Release date: | 2012-08-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly. Structure, 20, 2012
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2KXC
| 1H, 13C, and 15N Chemical Shift Assignments for IRTKS-SH3 and EspFu-R47 complex | Descriptor: | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, EspF-like protein | Authors: | Aitio, O, Hellman, M, Kazlauskas, A, Vingadassalom, D.F, Leong, J.M, Saksela, K, Permi, P. | Deposit date: | 2010-04-30 | Release date: | 2010-11-17 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Recognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assembly Proc.Natl.Acad.Sci.USA, 107, 2010
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1EFN
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7OJ9
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8C1V
| SARS-CoV-2 S-trimer (3 RBDs up) bound to TriSb92, fitted into cryo-EM map | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sb92, ... | Authors: | Huiskonen, J.T, Rissanen, I, Hannula, L. | Deposit date: | 2022-12-21 | Release date: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants. Nat Commun, 14, 2023
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3RBB
| HIV-1 NEF protein in complex with engineered HCK SH3 domain | Descriptor: | 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK | Authors: | Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M. | Deposit date: | 2011-03-29 | Release date: | 2011-04-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly. Traffic, 12, 2011
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4ORZ
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4D8D
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1QA5
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1QA4
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1AVV
| HIV-1 NEF PROTEIN, UNLIGANDED CORE DOMAIN | Descriptor: | NEGATIVE FACTOR | Authors: | Arold, S, Franken, P, Dumas, C. | Deposit date: | 1997-09-21 | Release date: | 1998-03-25 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling. Structure, 5, 1997
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1AVZ
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