2LNH

Enterohaemorrhagic E. coli (EHEC) exploits a tryptophan switch to hijack host F-actin assembly

Summary for 2LNH

DescriptorNeural Wiskott-Aldrich syndrome protein, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, Secreted effector protein EspF(U) (3 entities in total)
Functional Keywordsprotein complex, signaling protein-protein binding complex, signaling protein/protein binding
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm, cytoskeleton (By similarity) O00401
Cytoplasm, cytoskeleton Q9UHR4
Secreted (By similarity) P0DJ89
Total number of polymer chains3
Total molecular weight20123.6
Authors
Aitio, O.,Hellman, M.,Skehan, B.,Kesti, T.,Leong, J.M.,Saksela, K.,Permi, P. (deposition date: 2011-12-28, release date: 2012-08-29, Last modification date: 2012-10-31)
Primary citation
Aitio, O.,Hellman, M.,Skehan, B.,Kesti, T.,Leong, J.M.,Saksela, K.,Permi, P.
Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly.
Structure, 20:1692-1703, 2012
PubMed: 22921828 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2012.07.015
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers12.8%7.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload
167518
PDB entries from 2020-08-12