2LNH

Enterohaemorrhagic E. coli (EHEC) exploits a tryptophan switch to hijack host F-actin assembly

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Neural Wiskott-Aldrich syndrome protein	polymer	65	7262.0	1	UniProt (O00401) Pfam (PF00786) In PDB	Homo sapiens (human)	N-WASP
2	B	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1	polymer	67	7559.6	1	UniProt (Q9UHR4) Pfam (PF14604) In PDB	Homo sapiens (human)	BAI1-associated protein 2-like protein 1, Insulin receptor tyrosine kinase substrate
3	C	Secreted effector protein EspF(U)	polymer	48	5302.0	1	UniProt (P0DJ89) Pfam (PF04806) In PDB	Escherichia coli O157:H7	EspF-like protein encoded on prophage U, Tir-cytoskeleton coupling protein TccP

Sequence modifications

A: 2 - 65 (UniProt: O00401)

PDB	External Database	Details
Gly 1	-	EXPRESSION TAG

B: 69 - 132 (UniProt: Q9UHR4)

PDB	External Database	Details
Gly 66	-	EXPRESSION TAG
Ser 67	-	EXPRESSION TAG
His 68	-	EXPRESSION TAG

C: 133 - 179 (UniProt: P0DJ89)

PDB	External Database	Details
Gly 132	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	20123.6
All*	Total formula weight	20123.6

*Water molecules are not included.