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6EJL
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BU of 6ejl by Molmil
Structure of 14-3-3 zeta in complex with ASK1 14-3-3 binding motif
Descriptor: 14-3-3 protein zeta/delta, Mitogen-activated protein kinase kinase kinase 5
Authors:Petrvalska, O, Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2017-09-21
Release date:2017-11-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:Crystal structure of 14-3-3 zeta in complex with ASK1 14-3-3 binding motif
To Be Published
6QK8
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BU of 6qk8 by Molmil
Crystal structure of yeast 14-3-3 protein (Bmh1) from Saccharomyces cerevisiae with the Nha1p (yeast Na+/H+ antiporter) 14-3-3 binding motif Ser481
Descriptor: Na(+)/H(+) antiporter, Protein BMH1
Authors:Smidova, A, Obsil, T, Obsilova, V.
Deposit date:2019-01-28
Release date:2019-10-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.917 Å)
Cite:The activity of Saccharomyces cerevisiae Na+, K+/H+antiporter Nha1 is negatively regulated by 14-3-3 protein binding at serine 481.
Biochim Biophys Acta Mol Cell Res, 1866, 2019
6ZBT
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BU of 6zbt by Molmil
Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser342
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like
Authors:Joshi, R, Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2020-06-09
Release date:2021-07-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.79948521 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
6ZC9
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BU of 6zc9 by Molmil
Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser448
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like
Authors:Pohl, P, Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2020-06-10
Release date:2021-07-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.89895988 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
7NMZ
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BU of 7nmz by Molmil
Structure of 14-3-3 eta in complex with Nedd4-2(335-455) containing two 14-3-3 binding motifs Ser342 and Ser448
Descriptor: 14-3-3 protein eta, E3 ubiquitin-protein ligase NEDD4-like
Authors:Pohl, P, Obsil, T, Obsilova, V.
Deposit date:2021-02-23
Release date:2021-07-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
6Y4K
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BU of 6y4k by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and Fusicoccin A
Descriptor: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2, FUSICOCCIN
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2020-02-21
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
6Y6B
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BU of 6y6b by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and 16-OMe-Fusicoccin H
Descriptor: (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[[(1~{S},3~{R},6~{S},7~{S},8~{R},9~{R},10~{R},11~{R},14~{S})-14-(me thoxymethyl)-3,10-dimethyl-9-oxidanyl-6-propan-2-yl-8-tricyclo[9.3.0.0^{3,7}]tetradecanyl]oxy]oxane-3,4,5-triol, 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2020-02-26
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
7A6Y
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BU of 7a6y by Molmil
Structure of 14-3-3 gamma in complex with DAPK2 peptide stabilized by FC-A
Descriptor: 14-3-3 protein gamma, DAPK2 C-terminal peptide, FUSICOCCIN
Authors:Horvath, M, Obsilova, V, Obsil, T.
Deposit date:2020-08-27
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.
Commun Biol, 4, 2021
7A6R
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BU of 7a6r by Molmil
Structure of 14-3-3 gamma in complex with DAPK2 peptide containing the 14-3-3 binding motif
Descriptor: 14-3-3 protein gamma, DAPK2 C-terminal peptide
Authors:Horvath, M, Obsilova, V, Obsil, T.
Deposit date:2020-08-26
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.
Commun Biol, 4, 2021
6S9K
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BU of 6s9k by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 peptide containing 14-3-3 binding motif Ser139 and NLS
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, Caspase-2
Authors:Alblova, M, Obsil, T, Obsilova, V.
Deposit date:2019-07-15
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
6SAD
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BU of 6sad by Molmil
Structure of 14-3-3 gamma in complex with double phosphorylated caspase-2 peptide on Ser139 and Ser164
Descriptor: 14-3-3 protein gamma, Caspase-2
Authors:Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2019-07-16
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
6EWW
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BU of 6eww by Molmil
Structure of 14-3-3 zeta in complex with CaMKK2 14-3-3 binding motif
Descriptor: 14-3-3 protein zeta/delta, ARG-LYS-LEU-SEP-LEU-GLN-GLU-ARG
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2017-11-06
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.679 Å)
Cite:14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018
6FEL
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BU of 6fel by Molmil
Structure of 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser511
Descriptor: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2018-01-02
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018

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數據於2024-07-03公開中

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