1YGE
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![BU of 1yge by Molmil](/molmil-images/mine/1yge) | LIPOXYGENASE-1 (SOYBEAN) AT 100K | Descriptor: | FE (III) ION, LIPOXYGENASE-1 | Authors: | Minor, W, Steczko, J, Stec, B, Otwinowski, Z, Bolin, J.T, Walter, R, Axelrod, B. | Deposit date: | 1996-06-04 | Release date: | 1997-07-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution. Biochemistry, 35, 1996
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6GZM
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![BU of 6gzm by Molmil](/molmil-images/mine/6gzm) | Crystal Structure of Human CKIdelta with A86 | Descriptor: | CITRIC ACID, Casein kinase I isoform delta, GLYCEROL, ... | Authors: | Ben-neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J. | Deposit date: | 2018-07-04 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell, 175, 2018
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6GZD
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![BU of 6gzd by Molmil](/molmil-images/mine/6gzd) | Crystal structure of Human CSNK1A1 with A86 | Descriptor: | 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, Casein kinase I isoform alpha, ... | Authors: | Ben-Neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J. | Deposit date: | 2018-07-03 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell, 175, 2018
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6GZH
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![BU of 6gzh by Molmil](/molmil-images/mine/6gzh) | Crystal Structure of Human CDK9/cyclinT1 with A86 | Descriptor: | Cyclin-T1, Cyclin-dependent kinase 9, GLYCEROL, ... | Authors: | Ben-neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J. | Deposit date: | 2018-07-04 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell, 175, 2018
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4XK4
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![BU of 4xk4 by Molmil](/molmil-images/mine/4xk4) | E. coli transcriptional regulator RUTR with dihydrouracil | Descriptor: | DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE, HTH-type transcriptional regulator RutR | Authors: | Shumilin, I.A, Cooper, D.R, Shabalin, I.G, Grabowski, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2015-01-09 | Release date: | 2015-05-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | E. COLI TRANSCRIPTIONAL REGULATOR RUTR WITH DIHYDROURACIL to be published
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3L8J
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![BU of 3l8j by Molmil](/molmil-images/mine/3l8j) | Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity | Descriptor: | Programmed cell death protein 10 | Authors: | Li, X, Zhang, R, Zhang, H, He, Y, Ji, W, Min, W, Boggon, T.J. | Deposit date: | 2009-12-31 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity. J.Biol.Chem., 285, 2010
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5VPL
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![BU of 5vpl by Molmil](/molmil-images/mine/5vpl) | CRYSTAL STRUCTURE OF DER F 1 COMPLEXED WITH FAB 4C1 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C1 - HEAVY CHAIN, ... | Authors: | Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W. | Deposit date: | 2017-05-05 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens. J.Biol.Chem., 287, 2012
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4OG1
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![BU of 4og1 by Molmil](/molmil-images/mine/4og1) | Crystal Structure of a Putative Enoyl-CoA Hydratase from Novosphingobium aromaticivorans DSM 12444 | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Enoyl-CoA hydratase/isomerase | Authors: | Chapman, H.C, Cooper, D.R, Tkaczuk, K.L, Cymborowski, M.T, Stead, M, Hillerich, B, Ahmed, M, Bonanno, J.B, Seidel, R, Alkire, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-01-15 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal Structure of a Putative Enoyl-CoA Hydratase from Novosphingobium aromaticivorans DSM 12444 To be Published
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4OAE
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![BU of 4oae by Molmil](/molmil-images/mine/4oae) | Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol | Descriptor: | 1,2-ETHANEDIOL, CHLORAMPHENICOL, GNAT superfamily acetyltransferase PA4794, ... | Authors: | Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-01-04 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol To be Published
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5W90
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![BU of 5w90 by Molmil](/molmil-images/mine/5w90) | FEZ-1 metallo-beta-lactamase from Legionella gormanii modelled with unknown ligand | Descriptor: | FEZ-1 protein, GLYCEROL, SULFATE ION, ... | Authors: | Garcia-Saez, I, Mercuri, P.S, Kahn, R, Shabalin, I.G, Raczynska, J.E, Jaskolski, M, Minor, W, Papamicael, C, Frere, J.M, Galleni, M, Dideberg, O. | Deposit date: | 2017-06-22 | Release date: | 2018-06-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril. J. Mol. Biol., 325, 2003
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6XK0
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![BU of 6xk0 by Molmil](/molmil-images/mine/6xk0) | Albumin-dexamethasone complex | Descriptor: | Albumin, CITRATE ANION, DEXAMETHASONE, ... | Authors: | Czub, M.P, Majorek, K.A, Shabalin, I.G, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2020-06-24 | Release date: | 2020-07-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy. Iucrj, 7, 2020
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5DQF
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![BU of 5dqf by Molmil](/molmil-images/mine/5dqf) | Horse Serum Albumin (ESA) in complex with Cetirizine | Descriptor: | (2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid, (2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid, CHLORIDE ION, ... | Authors: | Handing, K.B, Shabalin, I.G, Majorek, K.A, Chruszcz, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2015-09-14 | Release date: | 2015-12-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of equine serum albumin in complex with cetirizine reveals a novel drug binding site. Mol.Immunol., 71, 2016
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3TYS
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![BU of 3tys by Molmil](/molmil-images/mine/3tys) | Crystal structure of transcriptional regulator VanUg, Form II | Descriptor: | Predicted transcriptional regulator | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Depardieu, F, Courvalin, P, Shabalin, I, Chruszcz, M, Minor, W, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-09-26 | Release date: | 2011-10-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.121 Å) | Cite: | Crystal structure of transcriptional regulator VanUg, Form II TO BE PUBLISHED
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3TYR
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![BU of 3tyr by Molmil](/molmil-images/mine/3tyr) | Crystal structure of transcriptional regulator VanUg, Form I | Descriptor: | Transcriptional regulator | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Dong, A, Depardieu, F, Courvalin, P, Shabalin, I, Chruszcz, M, Minor, W, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-09-26 | Release date: | 2011-10-12 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Crystal structure of transcriptional regulator VanUg, Form I TO BE PUBLISHED
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3TZC
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![BU of 3tzc by Molmil](/molmil-images/mine/3tzc) | Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(Y155F) from Vibrio cholerae | Descriptor: | 3-oxoacyl-[acyl-carrier protein] reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | Authors: | Hou, J, Chruszcz, M, Zheng, H, Grabowski, M, Domagalski, M, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-09-27 | Release date: | 2011-10-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae. J.Bacteriol., 198, 2015
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3UDU
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![BU of 3udu by Molmil](/molmil-images/mine/3udu) | Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni | Descriptor: | 1,2-ETHANEDIOL, 3-isopropylmalate dehydrogenase, CHLORIDE ION | Authors: | Tkaczuk, K.L, Chruszcz, M, Grimshaw, S, Onopriyenko, O, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-10-28 | Release date: | 2011-11-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni To be Published
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3UEG
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![BU of 3ueg by Molmil](/molmil-images/mine/3ueg) | Crystal structure of human Survivin K62A mutant | Descriptor: | 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 5, TETRAETHYLENE GLYCOL, ... | Authors: | Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W. | Deposit date: | 2011-10-30 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol.Biol.Cell, 23, 2012
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3UEC
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![BU of 3uec by Molmil](/molmil-images/mine/3uec) | Crystal structure of human Survivin bound to histone H3 phosphorylated on threonine-3. | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Baculoviral IAP repeat-containing protein 5, ... | Authors: | Niedzialkowska, E, Porebski, P.J, Cooper, D.R, Chruszcz, M, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W. | Deposit date: | 2011-10-30 | Release date: | 2012-03-07 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol.Biol.Cell, 23, 2012
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3UEI
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![BU of 3uei by Molmil](/molmil-images/mine/3uei) | Crystal structure of human Survivin E65A mutant | Descriptor: | Baculoviral IAP repeat-containing protein 5, ZINC ION | Authors: | Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W. | Deposit date: | 2011-10-30 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol Biol Cell, 23, 2012
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3UDO
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![BU of 3udo by Molmil](/molmil-images/mine/3udo) | Crystal structure of putative isopropylamlate dehydrogenase from Campylobacter jejuni | Descriptor: | 1,2-ETHANEDIOL, 3-isopropylmalate dehydrogenase, SULFATE ION | Authors: | Tkaczuk, K.L, Chruszcz, M, Blus, B.J, Onopriyenko, O, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-10-28 | Release date: | 2011-11-09 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of putative isopropylamlate dehydrogenase from Campylobacter jejuni To be Published
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3UEF
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![BU of 3uef by Molmil](/molmil-images/mine/3uef) | Crystal structure of human Survivin bound to histone H3 (C2 space group). | Descriptor: | 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 5, N-terminal fragment of histone H3, ... | Authors: | Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W. | Deposit date: | 2011-10-30 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol.Biol.Cell, 23, 2012
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3UEH
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![BU of 3ueh by Molmil](/molmil-images/mine/3ueh) | Crystal structure of human Survivin H80A mutant | Descriptor: | 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 5, DI(HYDROXYETHYL)ETHER, ... | Authors: | Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W. | Deposit date: | 2011-10-30 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres. Mol Biol Cell, 23, 2012
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2FQ4
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![BU of 2fq4 by Molmil](/molmil-images/mine/2fq4) | The crystal structure of the transcriptional regulator (TetR family) from Bacillus cereus | Descriptor: | Transcriptional regulator, TetR family | Authors: | Zhang, R, Wu, R, Moy, S, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-01-17 | Release date: | 2006-02-28 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The crystal structure of the transcriptional regulator (TetR family) from Bacillus cereus To be Published
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2FU2
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![BU of 2fu2 by Molmil](/molmil-images/mine/2fu2) | Crystal structure of protein SPy2152 from Streptococcus pyogenes | Descriptor: | Hypothetical protein SPy2152 | Authors: | Chang, C, Cymborowski, M, Otwinowski, Z, Minor, W, Lezondra, L.-E, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-01-25 | Release date: | 2006-03-07 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes. Bmc Struct.Biol., 9, 2009
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2G3B
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![BU of 2g3b by Molmil](/molmil-images/mine/2g3b) | Crystal structure of putative TetR-family transcriptional regulator from Rhodococcus sp. | Descriptor: | GLYCEROL, putative TetR-family transcriptional regulator | Authors: | Chruszcz, M, Evdokimova, E, Cymborowski, M, Kagan, O, Wang, S, Koclega, K.D, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-02-17 | Release date: | 2006-03-14 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of putative TetR-family transcriptional regulator from Rhodococcus sp. To be Published
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