7TW9
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![BU of 7tw9 by Molmil](/molmil-images/mine/7tw9) | |
7TW7
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![BU of 7tw7 by Molmil](/molmil-images/mine/7tw7) | |
7TW8
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![BU of 7tw8 by Molmil](/molmil-images/mine/7tw8) | |
8U7B
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8FRJ
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![BU of 8frj by Molmil](/molmil-images/mine/8frj) | Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946 | Descriptor: | 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Transcription factor ETV6,Guanine-N7 methyltransferase nsp14 chimera, ZINC ION | Authors: | Kottur, J, Aggarwal, A.K. | Deposit date: | 2023-01-07 | Release date: | 2023-07-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. Plos Pathog., 19, 2023
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8FRK
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4Q43
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![BU of 4q43 by Molmil](/molmil-images/mine/4q43) | Polymerase-damaged DNA complex | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*T*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*TP*CP*TP*(RDG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Kottur, J, Sharma, A, Nair, D.T. | Deposit date: | 2014-04-13 | Release date: | 2015-05-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic Structure, 23, 2015
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4Q45
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![BU of 4q45 by Molmil](/molmil-images/mine/4q45) | DNA Polymerase- damaged DNA complex | Descriptor: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*TP*CP*TP*A*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*TP*CP*TP*AP*GP*GP*(RDG)P*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... | Authors: | Kottur, J, Sharma, A, Nair, D.T. | Deposit date: | 2014-04-13 | Release date: | 2015-05-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.176 Å) | Cite: | Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic Structure, 23, 2015
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6IG1
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![BU of 6ig1 by Molmil](/molmil-images/mine/6ig1) | DNA polymerase IV - DNA ternary complex 10 | Descriptor: | DIPHOSPHATE, DNA polymerase IV, DTN3, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2018-09-21 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction. Nucleic Acids Res., 46, 2018
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5YUY
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![BU of 5yuy by Molmil](/molmil-images/mine/5yuy) | DNA polymerase IV - DNA ternary complex 9 | Descriptor: | DIPHOSPHATE, DNA polymerase IV, DTN, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-10-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YUR
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![BU of 5yur by Molmil](/molmil-images/mine/5yur) | DNA polymerase IV - DNA ternary complex 1 | Descriptor: | DNA polymerase IV, DTN, SODIUM ION, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.035 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YUT
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![BU of 5yut by Molmil](/molmil-images/mine/5yut) | DNA polymerase IV - DNA ternary complex 3 | Descriptor: | DNA polymerase IV, DTN, MAGNESIUM ION, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YUZ
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![BU of 5yuz by Molmil](/molmil-images/mine/5yuz) | DNA polymerase IV - DNA ternary complex 11 | Descriptor: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-11-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction. Nucleic Acids Res., 46, 2018
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5YYE
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![BU of 5yye by Molmil](/molmil-images/mine/5yye) | DNA polymerase IV - ternary complex 16 | Descriptor: | 5'-O-[hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]thymidine, DNA polymerase IV, DTN2, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-12-08 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.325 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YUW
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![BU of 5yuw by Molmil](/molmil-images/mine/5yuw) | DNA polymerase IV - DNA ternary complex 6 | Descriptor: | DNA polymerase IV, DTN1, DTN2C, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.124 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YV1
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![BU of 5yv1 by Molmil](/molmil-images/mine/5yv1) | DNA polymerase IV - DNA ternary complex 13 | Descriptor: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YV0
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![BU of 5yv0 by Molmil](/molmil-images/mine/5yv0) | DNA polymerase IV - DNA ternary complex 12 | Descriptor: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-11-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction. Nucleic Acids Res., 46, 2018
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5YUS
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![BU of 5yus by Molmil](/molmil-images/mine/5yus) | DNA polymerase IV - DNA ternary complex 2 | Descriptor: | DNA polymerase IV, DTN, MAGNESIUM ION, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-11-07 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5ZLV
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![BU of 5zlv by Molmil](/molmil-images/mine/5zlv) | |
5YV3
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![BU of 5yv3 by Molmil](/molmil-images/mine/5yv3) | DNA polymerase IV - DNA ternary complex 7 | Descriptor: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YUU
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![BU of 5yuu by Molmil](/molmil-images/mine/5yuu) | DNA polymerase IV - DNA ternary complex 4 | Descriptor: | DNA polymerase IV, DTN1, DTN2, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.892 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YUV
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![BU of 5yuv by Molmil](/molmil-images/mine/5yuv) | DNA polymerase IV - DNA ternary complex 5 | Descriptor: | DNA polymerase IV, DTN1, DTN2, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-10-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YUX
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![BU of 5yux by Molmil](/molmil-images/mine/5yux) | DNA polymerase IV - DNA ternary complex 8 | Descriptor: | DIPHOSPHATE, DNA polymerase IV, DTN1, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-12-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YV2
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![BU of 5yv2 by Molmil](/molmil-images/mine/5yv2) | DNA polymerase IV - DNA ternary complex 14 | Descriptor: | DNA polymerase IV, DTN1, DTN2, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-11-23 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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5YYD
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![BU of 5yyd by Molmil](/molmil-images/mine/5yyd) | DNA polymerase IV - ternary complex 15 | Descriptor: | 5'-O-[hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]thymidine, DNA polymerase IV, DTN2, ... | Authors: | Kottur, J, Nair, D.T. | Deposit date: | 2017-12-08 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
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