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1Q5T
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BU of 1q5t by Molmil
Gln48 PLA2 separated from Vipoxin from the venom of Vipera ammodytes meridionalis.
Descriptor: Phospholipase A2 inhibitor, SULFATE ION
Authors:Georgieva, D.N, Perbandt, M, Rypniewski, W, Hristov, K, Genov, N, Betzel, C.
Deposit date:2003-08-11
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The X-ray structure of a snake venom Gln48 phospholipase A2 at 1.9A resolution reveals anion-binding sites.
Biochem.Biophys.Res.Commun., 316, 2004
6NK2
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BU of 6nk2 by Molmil
EphA2 LBD in complex with bA-WLA-YRPK bio peptide
Descriptor: DI(HYDROXYETHYL)ETHER, Ephrin type-A receptor 2, bA-WLA-YPRKbio peptide
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2019-01-04
Release date:2019-05-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
7B7N
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BU of 7b7n by Molmil
Human herpesvirus-8 gH/gL in complex with EphA2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Pederzoli, R, Guardado-Calvo, P, Rey, F.A, Backovic, M.
Deposit date:2020-12-11
Release date:2020-12-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.
Plos Biol., 19, 2021
4M8H
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BU of 4m8h by Molmil
CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (R)4-METHYL 9cUAB30 AND COACTIVATOR PEPTIDE GRIP-1
Descriptor: (2E,6Z,8E)-3,7-dimethyl-8-[(4R)-4-methyl-3,4-dihydronaphthalen-1(2H)-ylidene]octa-2,6-dienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
Authors:Xia, G, Smith, C.D, Muccio, D.D.
Deposit date:2013-08-13
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention.
Bioorg.Med.Chem., 22, 2014
4M8E
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BU of 4m8e by Molmil
CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (S) 4-Methyl 9cUAB30 COACTIVATOR PEPTIDE GRIP-1
Descriptor: (3E,6Z,8E)-3,7-dimethyl-8-[(4S)-4-methyl-3,4-dihydronaphthalen-1(2H)-ylidene]octa-3,6-dienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
Authors:Xia, G, Smith, C.D, Muccio, D.D.
Deposit date:2013-08-13
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention.
Bioorg.Med.Chem., 22, 2014
2LZL
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BU of 2lzl by Molmil
FGFR3tm
Descriptor: Fibroblast growth factor receptor 3
Authors:Lesovoy, D.M, Bocharov, E.V, Goncharuk, S.A, Arseniev, A.S.
Deposit date:2012-10-04
Release date:2013-10-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies.
Structure, 21, 2013
7KJB
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BU of 7kjb by Molmil
Crystal structure of the EphA2 S897E/S901E mutant intracellular KD-SAM domains
Descriptor: CESIUM ION, Ephrin type-A receptor 2
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2020-10-26
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker.
Nat Commun, 12, 2021
7KJA
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BU of 7kja by Molmil
Crystal structure of the EphA2 intracellular KD-SAM domains
Descriptor: Ephrin type-A receptor 2, GLYCEROL, MAGNESIUM ION, ...
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2020-10-26
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker.
Nat Commun, 12, 2021
7KJC
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BU of 7kjc by Molmil
Crystal structure of the EphA2 S901E mutant intracellular KD-SAM domains
Descriptor: Ephrin type-A receptor 2, GLYCEROL, MAGNESIUM ION, ...
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2020-10-26
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker.
Nat Commun, 12, 2021
6NK0
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BU of 6nk0 by Molmil
EphA2 LBD in complex with bA-WLA-Yam peptide
Descriptor: 1,2-ETHANEDIOL, 6-AMINOHEXANOIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2019-01-04
Release date:2019-05-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
6NKP
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BU of 6nkp by Molmil
EphA2 LBD in complex with bA-WLA-YSKbio peptide
Descriptor: BIOTIN, Ephrin type-A receptor 2, bA-WLA-YSKbio peptide
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2019-01-07
Release date:2019-05-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.033 Å)
Cite:Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
6NJZ
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BU of 6njz by Molmil
EphA2 LBD in complex with YSA-GSGSK-bio peptide
Descriptor: BIOTIN, Ephrin type-A receptor 2, GLYCEROL, ...
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2019-01-04
Release date:2019-05-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
6NK1
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BU of 6nk1 by Molmil
EphA2 LBD in complex with bA-WLA-YRPKbio peptide
Descriptor: ACETATE ION, Ephrin type-A receptor 2, GLYCEROL, ...
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2019-01-04
Release date:2019-05-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019

222036

數據於2024-07-03公開中

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