2H65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h65 by Molmil](/molmil-images/mine/2h65) | Crystal strusture of caspase-3 with inhibitor Ac-VDVAD-Cho | Descriptor: | Ac-VDVAD-Cho, caspase-3, p12 subunit, ... | Authors: | Fang, B, Boross, P.I, Tozser, J, Weber, I.T. | Deposit date: | 2006-05-30 | Release date: | 2006-09-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition J.Mol.Biol., 360, 2006
|
|
2H5J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h5j by Molmil](/molmil-images/mine/2h5j) | Crystal strusture of caspase-3 with inhibitor Ac-DMQD-Cho | Descriptor: | Ac-DMQD-Cho, caspase-3, p12 subunit, ... | Authors: | Fang, B, Boross, P.I, Tozser, J, Weber, I.T. | Deposit date: | 2006-05-26 | Release date: | 2006-09-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition J.Mol.Biol., 360, 2006
|
|
2H5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h5i by Molmil](/molmil-images/mine/2h5i) | Crystal structure of caspase-3 with inhibitor Ac-DEVD-Cho | Descriptor: | Ac-DEV(ASJ), caspase-3, p12 subunit, ... | Authors: | Fang, B, Boross, P.I, Tozser, J, Weber, I.T. | Deposit date: | 2006-05-26 | Release date: | 2006-09-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition J.Mol.Biol., 360, 2006
|
|
3GJS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gjs by Molmil](/molmil-images/mine/3gjs) | Caspase-3 Binds Diverse P4 Residues in Peptides | Descriptor: | Ac-YVAD-Cho inhibitor, Caspase-3 subunit p12, Caspase-3 subunit p17 | Authors: | Fang, B, Fu, G, Agniswamy, J, Harrison, R.W, Weber, I.T. | Deposit date: | 2009-03-09 | Release date: | 2009-03-24 | Last modified: | 2011-08-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling. Apoptosis, 14, 2009
|
|
3GJR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gjr by Molmil](/molmil-images/mine/3gjr) | Caspase-3 Binds Diverse P4 Residues in Peptides | Descriptor: | Caspase-3 subunit p12, Caspase-3 subunit p17, GLYCEROL, ... | Authors: | Fang, B, Fu, G, Agniswamy, J, Harrison, R.W, Weber, I.T. | Deposit date: | 2009-03-09 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling. Apoptosis, 14, 2009
|
|
3GJT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gjt by Molmil](/molmil-images/mine/3gjt) | Caspase-3 Binds Diverse P4 Residues in Peptides | Descriptor: | Caspase-3 subunit p12, Caspase-3 subunit p17, peptide inhibitor | Authors: | Fang, B, Fu, G, Agniswamy, J, Harrison, R.W, Weber, I.T. | Deposit date: | 2009-03-09 | Release date: | 2009-03-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling. Apoptosis, 14, 2009
|
|
3GJQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gjq by Molmil](/molmil-images/mine/3gjq) | Caspase-3 Binds Diverse P4 Residues in Peptides | Descriptor: | Caspase-3 subunit p12, Caspase-3 subunit p17, peptide inhibitor | Authors: | Fang, B, Fu, G, Agniswamy, J, Harrison, R.W, Weber, I.T. | Deposit date: | 2009-03-09 | Release date: | 2009-03-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling. Apoptosis, 14, 2009
|
|
8KFO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kfo by Molmil](/molmil-images/mine/8kfo) | Crystal structure of BSA in complex with B3 | Descriptor: | 6-[(~{E})-2-[1-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]pyridin-1-ium-4-yl]ethenyl]-~{N},~{N}-dimethyl-naphthalen-2-amine, Albumin | Authors: | Chen, X, Ge, Y.H, Yang, H, Fang, B, Li, L. | Deposit date: | 2023-08-16 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Bioinspired two-stage assembled photosensitive protein engineering for tumor-specific mitochondrial targeted phototherapy To Be Published
|
|
2QLJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qlj by Molmil](/molmil-images/mine/2qlj) | Crystal Structure of Caspase-7 with Inhibitor AC-WEHD-CHO | Descriptor: | CITRIC ACID, Caspase-7, Inhibitor AC-WEHD-CHO, ... | Authors: | Agniswamy, J, Fang, B, Weber, I. | Deposit date: | 2007-07-12 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
|
|
2QL5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ql5 by Molmil](/molmil-images/mine/2ql5) | Crystal Structure of caspase-7 with inhibitor AC-DMQD-CHO | Descriptor: | CITRIC ACID, Caspase-7, inhibitor, ... | Authors: | Agniswamy, J, Fang, B, Weber, I. | Deposit date: | 2007-07-12 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
|
|
2QL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ql9 by Molmil](/molmil-images/mine/2ql9) | Crystal Structure of Caspase-7 with inhibitor AC-DQMD-CHO | Descriptor: | CITRIC ACID, Caspase-7, Inhibitor AC-DQMD-CHO, ... | Authors: | Agniswamy, J, Fang, B, Weber, I. | Deposit date: | 2007-07-12 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
|
|
2QLF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qlf by Molmil](/molmil-images/mine/2qlf) | |
2QLB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qlb by Molmil](/molmil-images/mine/2qlb) | Crystal Structure of caspase-7 with inhibitor AC-ESMD-CHO | Descriptor: | CITRIC ACID, Caspase-7, Inhibitor AC-ESMD-CHO, ... | Authors: | Agniswamy, J, Fang, B, Weber, I. | Deposit date: | 2007-07-12 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
|
|
2QL7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ql7 by Molmil](/molmil-images/mine/2ql7) | Crystal Structure of Caspase-7 with inhibitor AC-IEPD-CHO | Descriptor: | CITRIC ACID, Caspase-7, Inhibitor AC-IEPD_CHO, ... | Authors: | Agniswamy, J, Fang, B, Weber, I. | Deposit date: | 2007-07-12 | Release date: | 2007-08-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
|
|
6LKG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lkg by Molmil](/molmil-images/mine/6lkg) | two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein, ... | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6LKK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lkk by Molmil](/molmil-images/mine/6lkk) | Two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6LKL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lkl by Molmil](/molmil-images/mine/6lkl) | Two-component system protein mediate signal transduction | Descriptor: | ABC transporter, solute-binding protein, MALONIC ACID | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.213 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6LKI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lki by Molmil](/molmil-images/mine/6lki) | Two-component system protein mediate signal transduction | Descriptor: | ABC transporter, solute-binding protein, MALONIC ACID, ... | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.781 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6LKJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lkj by Molmil](/molmil-images/mine/6lkj) | Two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-beta-D-galactopyranose, ABC transporter, solute-binding protein | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.004 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6LKH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lkh by Molmil](/molmil-images/mine/6lkh) | Two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein, ... | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2021-03-17 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.534 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
3IBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ibf by Molmil](/molmil-images/mine/3ibf) | Crystal structure of unliganded caspase-7 | Descriptor: | Caspase-7 | Authors: | Agniswamy, J. | Deposit date: | 2009-07-15 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7. Apoptosis, 14, 2009
|
|
3EDR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3edr by Molmil](/molmil-images/mine/3edr) | |
3IBC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ibc by Molmil](/molmil-images/mine/3ibc) | Crystal Structure of Caspase-7 incomplex with Acetyl-YVAD-CHO | Descriptor: | Acetyl-YVAD-CHO, Caspase-7 | Authors: | Agniswamy, J. | Deposit date: | 2009-07-15 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7. Apoptosis, 14, 2009
|
|
3EDQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3edq by Molmil](/molmil-images/mine/3edq) | Crystal structure of Caspase-3 with inhibitor AC-LDESD-CHO | Descriptor: | AC-LDESD-CHO peptide, Caspase-3 | Authors: | Fu, G. | Deposit date: | 2008-09-03 | Release date: | 2008-10-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Structural basis for executioner caspase recognition of P5 position in substrates. Apoptosis, 13, 2008
|
|
8X73
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8x73 by Molmil](/molmil-images/mine/8x73) | Crystal structure of Peroxiredoxin I in complex with compound 19-069 | Descriptor: | Peroxiredoxin-1, methyl (2~{S})-2-[[(2~{R},4~{a}~{S},6~{a}~{R},6~{a}~{S},14~{a}~{S},14~{b}~{R})-2,4~{a},6~{a},6~{a},9,14~{a}-hexamethyl-10-oxidanyl-11-oxidanylidene-1,3,4,5,6,13,14,14~{b}-octahydropicen-2-yl]carbamoylamino]-3-oxidanyl-propanoate | Authors: | Zhang, H, Luo, C. | Deposit date: | 2023-11-22 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors. J.Med.Chem., 67, 2024
|
|