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2JUQ
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BU of 2juq by Molmil
alpha-RgIA, a Novel Conotoxin that Blocks the alpha9-alpha10 nAChR
Descriptor: Alpha-conotoxin RgIA
Authors:Feng, Z, Ellison, M.
Deposit date:2007-09-02
Release date:2011-05-25
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.
J.Mol.Biol., 377, 2008
3JUA
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BU of 3jua by Molmil
Structural basis of YAP recognition by TEAD4 in the Hippo pathway
Descriptor: 65 kDa Yes-associated protein, Transcriptional enhancer factor TEF-3
Authors:Chen, L, Song, H.
Deposit date:2009-09-15
Release date:2010-02-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of YAP recognition by TEAD4 in the hippo pathway.
Genes Dev., 24, 2010
5HZ5
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BU of 5hz5 by Molmil
FABP5 in complex with 6-Chloro-4-phenyl-2-piperidin-1-yl-3-(1H-tetrazol-5-yl)-quinoline
Descriptor: 6-chloro-4-phenyl-2-(piperidin-1-yl)-3-(1H-tetrazol-5-yl)quinoline, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ...
Authors:Ehler, A, Rudolph, M.G.
Deposit date:2016-02-02
Release date:2017-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.
Bioorg. Med. Chem. Lett., 26, 2016
3J30
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BU of 3j30 by Molmil
Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab CHK152
Descriptor: CHK152 heavy chain, CHK152 light chain
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
3OZI
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BU of 3ozi by Molmil
Crystal structure of the TIR domain from the flax disease resistance protein L6
Descriptor: COBALT (II) ION, L6tr
Authors:Ve, T, Bernoux, M, Williams, S, Valkov, E, Warren, C, Hatters, D, Ellis, J.G, Dodds, P.N, Kobe, B.
Deposit date:2010-09-25
Release date:2011-04-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation.
Cell Host Microbe, 9, 2011
3J2Y
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BU of 3j2y by Molmil
Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab 9.8B
Descriptor: 9.8B heavy chain, 9.8B light chain
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (14.9 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
3QE7
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BU of 3qe7 by Molmil
Crystal Structure of Uracil Transporter--UraA
Descriptor: URACIL, Uracil permease, nonyl beta-D-glucopyranoside
Authors:Lu, F.R, Li, S, Yan, N.
Deposit date:2011-01-20
Release date:2011-03-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.781 Å)
Cite:Structure and mechanism of the uracil transporter UraA
Nature, 472, 2011
2JSZ
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BU of 2jsz by Molmil
Solution structure of Tpx in the reduced state
Descriptor: Probable thiol peroxidase
Authors:Jin, C, Lu, J, Yang, F.
Deposit date:2007-07-17
Release date:2008-07-22
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Reversible conformational switch revealed by the redox structures of Bacillus subtilis thiol peroxidase
Biochem.Biophys.Res.Commun., 373, 2008
3J2W
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BU of 3j2w by Molmil
Electron cryo-microscopy of Chikungunya virus
Descriptor: Capsid protein, Glycoprotein E1, Glycoprotein E2
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
5HZ6
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BU of 5hz6 by Molmil
FABP4 in complex with 6-Chloro-2-isopropyl-4-(3-isopropyl-phenyl)-quinoline-3-carboxylic acid
Descriptor: 6-Chloro-2-isopropyl-4-(3-isopropyl-phenyl)-quinoline-3-carboxylic acid, Fatty acid-binding protein, adipocyte
Authors:Ehler, A, Rudolph, M.G.
Deposit date:2016-02-02
Release date:2016-12-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.
Bioorg. Med. Chem. Lett., 26, 2016
3J2X
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BU of 3j2x by Molmil
Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab m242
Descriptor: m242 heavy chain, m242 light chain
Authors:Sun, S, Xiang, Y, Rossmann, M.G.
Deposit date:2013-01-28
Release date:2013-04-24
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (15.6 Å)
Cite:Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.
Elife, 2, 2013
7V8I
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BU of 7v8i by Molmil
LolCD(E171Q)E with bound AMPPNP in nanodiscs
Descriptor: Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolC, Lipoprotein-releasing system transmembrane protein LolE, ...
Authors:Bei, W.W, Luo, Q.S, Shi, H.G, Zhang, X.Z, Huang, Y.H.
Deposit date:2021-08-23
Release date:2022-08-31
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of LolCDE reveal the molecular mechanism of bacterial lipoprotein sorting in Escherichia coli.
Plos Biol., 20, 2022
7V8M
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BU of 7v8m by Molmil
LolCDE-apo in nanodiscs
Descriptor: Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolC, Lipoprotein-releasing system transmembrane protein LolE
Authors:Luo, Q.S, Bei, W.W, Shi, H.G, Zhang, X.Z, Huang, Y.H.
Deposit date:2021-08-23
Release date:2022-08-31
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structures of LolCDE reveal the molecular mechanism of bacterial lipoprotein sorting in Escherichia coli.
Plos Biol., 20, 2022
6GFW
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BU of 6gfw by Molmil
Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme initial transcribing complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Glyde, R, Ye, F.Z, Zhang, X.D.
Deposit date:2018-05-02
Release date:2018-07-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation.
Mol. Cell, 70, 2018
7V8L
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BU of 7v8l by Molmil
LolCDE with bound RcsF in nanodiscs
Descriptor: (2R)-3-{[(2S)-3-HYDROXY-2-(PALMITOYLAMINO)PROPYL]THIO}PROPANE-1,2-DIYL DIHEXADECANOATE, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolC, ...
Authors:Bei, W.W, Luo, Q.S, Shi, H.G, Zhang, X.Z, Huang, Y.H.
Deposit date:2021-08-23
Release date:2022-09-21
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of LolCDE reveal the molecular mechanism of bacterial lipoprotein sorting in Escherichia coli.
Plos Biol., 20, 2022
5G4C
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BU of 5g4c by Molmil
Human SIRT2 catalyse short chain fatty acyl lysine
Descriptor: CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, SIRT2, ...
Authors:Wang, Y.
Deposit date:2016-05-09
Release date:2017-05-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:SIRT2 Reverses 4-Oxononanoyl Lysine Modification on Histones.
J. Am. Chem. Soc., 138, 2016
6GH6
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BU of 6gh6 by Molmil
Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme intermediate partially loaded complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Glyde, R, Ye, F.Z, Zhang, X.D.
Deposit date:2018-05-04
Release date:2018-07-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation.
Mol. Cell, 70, 2018
5HZ8
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BU of 5hz8 by Molmil
FABP4_3 in complex with 6,8-Dichloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid
Descriptor: 6,8-dichloro-4-phenyl-2-(piperidin-1-yl)quinoline-3-carboxylic acid, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ...
Authors:Ehler, A, Rudolph, M.G.
Deposit date:2016-02-02
Release date:2016-12-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.
Bioorg. Med. Chem. Lett., 26, 2016
5HZ9
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BU of 5hz9 by Molmil
human FABP3 in complex with 6-Chloro-2-methyl-4-phenyl-quinoline-3-carboxylic acid
Descriptor: 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid, CHLORIDE ION, Fatty acid-binding protein, ...
Authors:Ehler, A, Rudolph, M.G.
Deposit date:2016-02-02
Release date:2016-12-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.
Bioorg. Med. Chem. Lett., 26, 2016
6KIG
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BU of 6kig by Molmil
Structure of cyanobacterial photosystem I-IsiA supercomplex
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Cao, P, Cao, D.F, Si, L, Su, X.D, Chang, W.R, Liu, Z.F, Zhang, X.Z, Li, M.
Deposit date:2019-07-18
Release date:2020-02-12
Last modified:2020-03-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for energy and electron transfer of the photosystem I-IsiA-flavodoxin supercomplex.
Nat.Plants, 6, 2020
4PHW
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BU of 4phw by Molmil
Crystal Structure of PDE10A with 1H-benzimidazol-2-yl(4-((3-(tetrahydro-2H-pyran-4-yl)-2-pyridinyl)oxy)phenyl)methanone
Descriptor: 1H-benzimidazol-2-yl(4-{[3-(tetrahydro-2H-pyran-4-yl)pyridin-2-yl]oxy}phenyl)methanone, SULFATE ION, ZINC ION, ...
Authors:Chmait, S.
Deposit date:2014-05-07
Release date:2014-08-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of Clinical Candidate 1-(4-(3-(4-(1H-Benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), A Potent, Selective, and Efficacious Inhibitor of Phosphodiesterase 10A (PDE10A).
J.Med.Chem., 57, 2014
7F6V
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BU of 7f6v by Molmil
Cryo-EM structure of the human TACAN channel in a closed state
Descriptor: CHOLESTEROL, Ion channel TACAN
Authors:Chen, X.Z, Wang, Y.J, Li, Y, Yang, X, Shen, Y.Q.
Deposit date:2021-06-25
Release date:2022-02-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Cryo-EM structure of the human TACAN in a closed state.
Cell Rep, 38, 2022
2JUT
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BU of 2jut by Molmil
alpha RgIA, a Novel Conotoxin that Blocks the alpha9-alpha10 nAChR
Descriptor: Alpha-conotoxin RgIA
Authors:Feng, Z, Ellison, M.
Deposit date:2007-09-02
Release date:2011-05-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.
J.Mol.Biol., 377, 2008
2JSY
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BU of 2jsy by Molmil
Solution structure of Tpx in the oxidized state
Descriptor: Probable thiol peroxidase
Authors:Jin, C, Lu, J.
Deposit date:2007-07-17
Release date:2008-07-22
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Reversible conformational switch revealed by the redox structures of Bacillus subtilis thiol peroxidase
Biochem.Biophys.Res.Commun., 373, 2008
4NBN
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BU of 4nbn by Molmil
Tailoring Small Molecules for an Allosteric Site on Procaspase-6
Descriptor: 2,2'-[pyrimidine-4,6-diylbis(iminomethanediyl)]diphenol, Caspase-6, PHOSPHATE ION
Authors:Murray, J.M, Steffek, M.
Deposit date:2013-10-23
Release date:2013-12-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Tailoring small molecules for an allosteric site on procaspase-6.
Chemmedchem, 9, 2014

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數據於2024-09-11公開中

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