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2K3J
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BU of 2k3j by Molmil
The solution structure of human Mia40
Descriptor: Mitochondrial intermembrane space import and assembly protein 40
Authors:Ciofi Baffoni, S, Bertini, I, Gallo, A.
Deposit date:2008-05-08
Release date:2009-02-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria.
Nat.Struct.Mol.Biol., 16, 2009
2GQM
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BU of 2gqm by Molmil
Solution structure of Human Cu(I)-Sco1
Descriptor: COPPER (I) ION, SCO1 protein homolog, mitochondrial
Authors:Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE)
Deposit date:2006-04-21
Release date:2006-06-06
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:A hint for the function of human Sco1 from different structures.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2JSC
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BU of 2jsc by Molmil
NMR structure of the cadmium metal-sensor CMTR from Mycobacterium tuberculosis
Descriptor: CADMIUM ION, Transcriptional regulator Rv1994c/MT2050
Authors:Banci, L, Bertini, I, Cantini, F, Ciofi-Baffoni, S, Cavet, J.S, Dennison, C, Graham, A.I, Harvie, D.R, Robinson, N.J, Structural Proteomics in Europe (SPINE)
Deposit date:2007-07-02
Release date:2007-07-31
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:NMR Structural Analysis of Cadmium Sensing by Winged Helix Repressor CmtR.
J.Biol.Chem., 282, 2007
2K6Z
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BU of 2k6z by Molmil
Solution structures of copper loaded form PCuA (trans conformation of the peptide bond involving the nitrogen of P14)
Descriptor: COPPER (I) ION, Putative uncharacterized protein TTHA1943
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P.A, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-28
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
2K70
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BU of 2k70 by Molmil
Solution structures of copper loaded form PCuA (cis conformation of the peptide bond involving the nitrogen of P14)
Descriptor: COPPER (I) ION, Putative uncharacterized protein TTHA1943
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P.A, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-29
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
2K6W
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BU of 2k6w by Molmil
Solution structures of apo PCuA (trans conformation of the peptide bond involving the nitrogen of P14)
Descriptor: Putative uncharacterized protein TTHA1943
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-28
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
2K6V
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BU of 2k6v by Molmil
Solution structures of apo Sco1 protein from Thermus Thermophilus
Descriptor: Putative cytochrome c oxidase assembly protein
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-28
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
2K9C
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BU of 2k9c by Molmil
Paramagnetic shifts in solid-state NMR of Proteins to elicit structural information
Descriptor: COBALT (II) ION, Macrophage metalloelastase
Authors:Balayssac, S, Bertini, I, Bhaumik, A, Lelli, M, Luchinat, C.
Deposit date:2008-10-08
Release date:2008-11-18
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Paramagnetic shifts in solid-state NMR of proteins to elicit structural information
Proc.Natl.Acad.Sci.Usa, 105, 2008
3F19
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BU of 3f19 by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor 4-fluoro-N-(2-nitroso-2-oxoethyl)benzenesulfonamide
Descriptor: 2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide, CALCIUM ION, Macrophage metalloelastase, ...
Authors:Calderone, V.
Deposit date:2008-10-27
Release date:2008-11-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
J.Am.Chem.Soc., 129, 2007
3F16
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BU of 3f16 by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-N-(3-hydroxy-1-nitroso-1-oxopropan-2-yl)-4-methoxybenzenesulfonamide
Descriptor: (2R)-3-hydroxy-2-[(4-methoxyphenyl)sulfonylamino]-N-oxo-propanamide, CALCIUM ION, Macrophage metalloelastase, ...
Authors:Calderone, V.
Deposit date:2008-10-27
Release date:2008-11-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
J.Am.Chem.Soc., 129, 2007
3F17
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BU of 3f17 by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-(2-nitroso-2-oxoethyl)biphenyl-4-sulfonamide
Descriptor: CALCIUM ION, Macrophage metalloelastase, N-oxidanyl-2-[(4-phenylphenyl)sulfonylamino]ethanamide, ...
Authors:Calderone, V.
Deposit date:2008-10-27
Release date:2008-11-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
J.Am.Chem.Soc., 129, 2007
3F15
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BU of 3f15 by Molmil
Crystal structure of the catalytic domain of human mmp12 complexed with the inhibitor (S)-N-(2,3-dihydroxypropyl)-4-methoxy-N-(2-nitroso-2-oxoethyl)benzenesulfonamide
Descriptor: 2-[[(2S)-2,3-dihydroxypropyl]-(4-methoxyphenyl)sulfonyl-amino]-N-oxo-ethanamide, CALCIUM ION, Macrophage metalloelastase, ...
Authors:Calderone, V.
Deposit date:2008-10-27
Release date:2008-11-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
J.Am.Chem.Soc., 129, 2007
3F1A
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BU of 3f1a by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-(2-nitroso-2-oxoethyl)benzenesulfonamide
Descriptor: CALCIUM ION, Macrophage metalloelastase, N-oxo-2-(phenylsulfonylamino)ethanamide, ...
Authors:Calderone, V.
Deposit date:2008-10-27
Release date:2008-11-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
J.Am.Chem.Soc., 129, 2007
3F18
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BU of 3f18 by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor 4-fluoro-N-(2-hydroxyethyl)-N-(2-nitroso-2-oxoethyl)benzenesulfonamide
Descriptor: 2-[(4-fluorophenyl)sulfonyl-(2-hydroxyethyl)amino]-N-oxo-ethanamide, CALCIUM ION, Macrophage metalloelastase, ...
Authors:Calderone, V.
Deposit date:2008-10-27
Release date:2008-11-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases.
J.Am.Chem.Soc., 129, 2007
3LK8
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BU of 3lk8 by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor paramethoxy-sulfonyl-glycine hydroxamate
Descriptor: CALCIUM ION, Macrophage metalloelastase, N-hydroxy-N~2~-[(4-methoxyphenyl)sulfonyl]glycinamide, ...
Authors:Calderone, V.
Deposit date:2010-01-27
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases
J.Am.Chem.Soc., 129, 2007
4IJO
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BU of 4ijo by Molmil
Unraveling hidden allosteric regulatory sites in structurally homologues metalloproteases
Descriptor: CALCIUM ION, Macrophage metalloelastase, ZINC ION
Authors:Udi, Y, Fragai, M, Grossman, M, Mitternacht, S, Arad-Yellin, R, Calderone, V, Melikian, M, Toccafondi, M, Berezovsky, I.N, Luchinat, C, Sagi, I.
Deposit date:2012-12-22
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Unraveling hidden regulatory sites in structurally homologous metalloproteases
J.Mol.Biol., 425, 2013
3ECW
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BU of 3ecw by Molmil
Crystal structure of the ALS-related pathological mutant T54R of human apo Cu,Zn Superoxide Dismutase (SOD1)
Descriptor: Superoxide dismutase [Cu-Zn]
Authors:Calderone, V.
Deposit date:2008-09-02
Release date:2009-05-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants.
Proc.Natl.Acad.Sci.USA, 106, 2009
3ECV
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BU of 3ecv by Molmil
Crystal structure of the ALS-related pathological mutant I113T of human apo Cu,Zn Superoxide Dismutase (SOD1)
Descriptor: Superoxide dismutase [Cu-Zn]
Authors:Calderone, V.
Deposit date:2008-09-02
Release date:2009-05-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants.
Proc.Natl.Acad.Sci.USA, 106, 2009
3ECU
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BU of 3ecu by Molmil
Crystal structure of human apo Cu,Zn Superoxide Dismutase (SOD1)
Descriptor: Superoxide dismutase [Cu-Zn]
Authors:Calderone, V.
Deposit date:2008-09-02
Release date:2009-05-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants.
Proc.Natl.Acad.Sci.USA, 106, 2009
5LAB
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BU of 5lab by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor NNGH
Descriptor: CALCIUM ION, Macrophage metalloelastase, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, ...
Authors:Ravera, E, Calderone, V, Luchinat, C.
Deposit date:2016-06-14
Release date:2016-08-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:First-principles calculation of pseudo-contact shifts in a paramagnetic metalloprotein
To Be Published
3NXA
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BU of 3nxa by Molmil
X-ray structure of the apo form of human S100A16
Descriptor: Protein S100-A16
Authors:Calderone, V.
Deposit date:2010-07-13
Release date:2010-11-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of human S100A16, a low-affinity calcium binder.
J.Biol.Inorg.Chem., 16, 2011
4GUY
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BU of 4guy by Molmil
Human MMP12 catalytic domain in complex with*N*-Hydroxy-2-(2-(4-methoxyphenyl)ethylsulfonamido)acetamide
Descriptor: CALCIUM ION, Macrophage metalloelastase, N-hydroxy-N~2~-{[2-(4-methoxyphenyl)ethyl]sulfonyl}glycinamide, ...
Authors:Calderone, V, Fragai, M, Luchinat, C, Massaro, A, Mordini, A, Mori, M.
Deposit date:2012-08-30
Release date:2012-09-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Contribution of free energy of solvation to ligand affinity in new potent MMPs inhibitors.
To be Published
1Y3K
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BU of 1y3k by Molmil
Solution structure of the apo form of the fifth domain of Menkes protein
Descriptor: Copper-transporting ATPase 1
Authors:Banci, L, Chasapis, C.T, Ciofi-Baffoni, S, Hadjiliadis, N, Rosato, A, Structural Proteomics in Europe (SPINE)
Deposit date:2004-11-25
Release date:2005-03-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein
Febs J., 272, 2005
1Y3J
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BU of 1y3j by Molmil
Solution structure of the copper(I) form of the fifth domain of Menkes protein
Descriptor: COPPER (II) ION, Copper-transporting ATPase 1
Authors:Banci, L, Chasapis, C.T, Ciofi-Baffoni, S, Hadjiliadis, N, Rosato, A, Structural Proteomics in Europe (SPINE)
Deposit date:2004-11-25
Release date:2005-03-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein
Febs J., 272, 2005
3N2V
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BU of 3n2v by Molmil
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-hydroxy-2-(N-hydroxyethyl)biphenyl-4-ylsulfonamido)acetamide
Descriptor: CALCIUM ION, Macrophage metalloelastase, N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide, ...
Authors:Calderone, V.
Deposit date:2010-05-19
Release date:2010-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs).
Eur.J.Med.Chem., 45, 2010

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數據於2024-10-30公開中

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