5LAB

Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor NNGH

Replaces:  1RMZ

Summary for 5LAB

• Entry DOI: 10.2210/pdb5lab/pdb
• Descriptor: Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: hydrolase mmp-12, hydrolase
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted, extracellular space, extracellular matrix : P39900
• Total number of polymer chains: 1
• Total formula weight: 18183.09

Authors

Ravera, E.,Calderone, V.,Luchinat, C. (deposition date: 2016-06-14, release date: 2016-08-10, Last modification date: 2024-02-07)

• Primary citation: Benda, L.,Mares, J.,Ravera, E.,Parigi, G.,Luchinat, C.,Kaupp, M.,Vaara, J.; First-principles calculation of pseudo-contact shifts in a paramagnetic metalloprotein; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.34 Å)