9BE1
| CG-centric NF-kappaB RelA binding DNA | Descriptor: | ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*G)-3'), ZINC ION | Authors: | Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G. | Deposit date: | 2024-04-13 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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6KMU
| P22/P10 complex of caspase-11 mutant C254A | Descriptor: | Caspase-4 | Authors: | Ding, J, Sun, Q. | Deposit date: | 2019-08-01 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. Cell, 180, 2020
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1CF5
| BETA-MOMORCHARIN STRUCTURE AT 2.55 A | Descriptor: | PROTEIN (BETA-MOMORCHARIN), beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yuan, Y.-R, He, Y.-N, Xiong, J.-P, Xia, Z.-X. | Deposit date: | 1999-03-24 | Release date: | 1999-06-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Three-dimensional structure of beta-momorcharin at 2.55 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
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6KMV
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6KH0
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4PT1
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5EQE
| Crystal structure of choline kinase alpha-1 bound by [4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]methanamine (compound 11) | Descriptor: | Choline kinase alpha, [4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]methanamine | Authors: | Zhou, T, Zhu, X, Dalgarno, D.C. | Deposit date: | 2015-11-12 | Release date: | 2016-01-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery. J.Med.Chem., 59, 2016
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5EQP
| Crystal structure of choline kinase alpha-1 bound by 6-[(4-methyl-1,4-diazepan-1-yl)methyl]quinoline (compound 37) | Descriptor: | 6-[(4-methyl-1,4-diazepan-1-yl)methyl]quinoline, Choline kinase alpha | Authors: | Zhou, T, Zhu, X, Dalgarno, D.C. | Deposit date: | 2015-11-13 | Release date: | 2016-01-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery. J.Med.Chem., 59, 2016
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7C8V
| Structure of sybody SR4 in complex with the SARS-CoV-2 S Receptor Binding domain (RBD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ... | Authors: | Li, T, Yao, H, Cai, H, Qin, W, Li, D. | Deposit date: | 2020-06-03 | Release date: | 2020-06-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
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7C8W
| Structure of sybody MR17 in complex with the SARS-CoV-2 S receptor-binding domain (RBD) | Descriptor: | GLYCEROL, Spike protein S1, Synthetic nanobody MR17, ... | Authors: | Li, T, Cai, H, Yao, H, Qin, W, Li, D. | Deposit date: | 2020-06-03 | Release date: | 2020-06-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
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7WJ6
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7WJ7
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7CAN
| Structure of sybody MR17-K99Y in complex with the SARS-CoV-2 S Receptor-binding domain (RBD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ... | Authors: | Li, T, Yao, H, Cai, H, Qin, W, Li, D. | Deposit date: | 2020-06-09 | Release date: | 2020-06-24 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
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3KFA
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8JC5
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8JCA
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7C96
| Avr1d:GmPUB13 U-box | Descriptor: | RING-type E3 ubiquitin transferase, RxLR effector protein Avh6 | Authors: | Xing, W, Hu, Q, Zhou, J, Yao, D. | Deposit date: | 2020-06-05 | Release date: | 2021-03-17 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Phytophthora sojae effector Avr1d functions as an E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection. Proc.Natl.Acad.Sci.USA, 118, 2021
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6IN8
| Crystal structure of MucB | Descriptor: | Sigma factor AlgU regulatory protein MucB | Authors: | Li, S, Zhang, Q, Bartlam, M. | Deposit date: | 2018-10-24 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa. Febs J., 286, 2019
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4GPI
| Crystal structure of human B type phosphoglycerate mutase | Descriptor: | CHLORIDE ION, Phosphoglycerate mutase 1 | Authors: | Zhou, L, He, C. | Deposit date: | 2012-08-21 | Release date: | 2013-05-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.0817 Å) | Cite: | Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nat Commun, 4, 2013
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4GPZ
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6IH0
| Aquifex aeolicus LpxC complex with ACHN-975 | Descriptor: | N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta -1,3-diynyl]benzamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, ... | Authors: | Li, D.Y, Fan, S, Jin, Y.Y, Zhang, C, Lv, G.X, Wu, G.T, Yang, Z.Y. | Deposit date: | 2018-09-27 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | The Complex Structure of Protein AaLpxC from Aquifex aeolicus with ACHN-975 Molecule Suggests an Inhibitory Mechanism at Atomic-Level against Gram-Negative Bacteria Molecules, 26, 2021
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4IN0
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7DR6
| PA28alpha-beta in complex with immunoproteasome | Descriptor: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | Authors: | Cong, Y, Xu, C. | Deposit date: | 2020-12-26 | Release date: | 2021-01-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM of mammalian PA28 alpha beta-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28 alpha beta. Nat Commun, 12, 2021
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6IN9
| Crystal structure of MucB in complex with MucA(peri) | Descriptor: | Sigma factor AlgU negative regulatory protein, Sigma factor AlgU regulatory protein MucB | Authors: | Li, S, Zhang, Q, Bartlam, M. | Deposit date: | 2018-10-24 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa. Febs J., 286, 2019
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7DR7
| bovine 20S immunoproteasome | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | Authors: | Xu, C, Cong, Y. | Deposit date: | 2020-12-26 | Release date: | 2021-01-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM of mammalian PA28 alpha beta-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28 alpha beta. Nat Commun, 12, 2021
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