4GPI

Crystal structure of human B type phosphoglycerate mutase

Summary for 4GPI

• Entry DOI: 10.2210/pdb4gpi/pdb
• Related: 1YFK
• Descriptor: Phosphoglycerate mutase 1, CHLORIDE ION (3 entities in total)
• Functional Keywords: alpha/beta, isomerase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 59869.66

Authors

Zhou, L.,He, C. (deposition date: 2012-08-21, release date: 2013-05-22, Last modification date: 2023-09-13)

• Primary citation: Hitosugi, T.,Zhou, L.,Fan, J.,Elf, S.,Zhang, L.,Xie, J.,Wang, Y.,Gu, T.L.,Aleckovic, M.,Leroy, G.,Kang, Y.,Kang, H.B.,Seo, J.H.,Shan, C.,Jin, P.,Gong, W.,Lonial, S.,Arellano, M.L.,Khoury, H.J.,Chen, G.Z.,Shin, D.M.,Khuri, F.R.,Boggon, T.J.,Kang, S.,He, C.,Chen, J.; Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.; Nat Commun, 4:1790-1790, 2013; PubMed: 23653202; DOI: 10.1038/ncomms2759

Experimental method

X-RAY DIFFRACTION (2.0817 Å)