1IPF
| TROPINONE REDUCTASE-II COMPLEXED WITH NADPH AND TROPINONE | Descriptor: | 8-METHYL-8-AZABICYCLO[3,2,1]OCTAN-3-ONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TROPINONE REDUCTASE-II | Authors: | Yamashita, A, Endo, M, Higashi, T, Nakatsu, T, Yamada, Y, Oda, J, Kato, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-05-09 | Release date: | 2003-06-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Capturing Enzyme Structure Prior to Reaction Initiation: Tropinone Reductase-II-Substrate Complexes BIOCHEMISTRY, 42, 2003
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1HIB
| THE STRUCTURE OF AN INTERLEUKIN-1 BETA MUTANT WITH REDUCED BIOACTIVITY SHOWS MULTIPLE SUBTLE CHANGES IN CONFORMATION THAT AFFECT PROTEIN-PROTEIN RECOGNITION | Descriptor: | INTERLEUKIN-1 BETA | Authors: | Camacho, N.P, Smith, D.R, Goldman, A, Schneider, B, Green, D, Young, P.R, Berman, H.M. | Deposit date: | 1993-03-29 | Release date: | 1994-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition. Biochemistry, 32, 1993
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1IES
| TETRAGONAL CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN | Descriptor: | CADMIUM ION, FERRITIN | Authors: | Granier, T, Gallois, B, Dautant, A, Langlois D'Estaintot, B, Precigoux, G. | Deposit date: | 1996-05-28 | Release date: | 1997-01-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Comparison of the structures of the cubic and tetragonal forms of horse-spleen apoferritin. Acta Crystallogr.,Sect.D, 53, 1997
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1HIV
| CRYSTAL STRUCTURE OF A COMPLEX OF HIV-1 PROTEASE WITH A DIHYDROETHYLENE-CONTAINING INHIBITOR: COMPARISONS WITH MOLECULAR MODELING | Descriptor: | 4-[(2R)-3-{[(1S,2S,3R,4S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methyl-4-({(1S,2R)-2-methyl-1-[(pyridin-2-ylmethyl)carbamoyl]butyl}carbamoyl)hexyl]amino}-2-{[(naphthalen-1-yloxy)acetyl]amino}-3-oxopropyl]-1H-imidazol-3-ium, HIV-1 PROTEASE | Authors: | Thanki, N, Wlodawer, A. | Deposit date: | 1992-02-12 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: comparisons with molecular modeling. Protein Sci., 1, 1992
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2Q16
| Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with ITP | Descriptor: | CALCIUM ION, HAM1 protein homolog, INOSINE 5'-TRIPHOSPHATE, ... | Authors: | Singer, A.U, Lam, R, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F. | Deposit date: | 2007-05-23 | Release date: | 2008-02-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374, 2007
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1ISZ
| Crystal structure of xylanase from Streptomyces olivaceoviridis E-86 complexed with galactose | Descriptor: | beta-D-galactopyranose, endo-1,4-beta-D-xylanase | Authors: | Fujimoto, Z, Kuno, A, Kaneko, S, Kobayashi, H, Kusakabe, I, Mizuno, H. | Deposit date: | 2001-12-27 | Release date: | 2002-02-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the sugar complexes of Streptomyces olivaceoviridis E-86 xylanase: sugar binding structure of the family 13 carbohydrate binding module. J.Mol.Biol., 316, 2002
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1QTT
| SOLUTION STRUCTURE OF THE ONCOPROTEIN P13MTCP1 | Descriptor: | PRODUCT OF THE MTCP1 ONCOGENE | Authors: | Guignard, L, Padilla, A, Mispelter, J, Yang, Y.-S, Stern, M.-H, Lhoste, J.-M, Roumestand, C. | Deposit date: | 1999-06-29 | Release date: | 2001-01-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Backbone dynamics and solution structure refinement of the 15N-labeled human oncogenic protein p13MTCP1: comparison with X-ray data. J.Biomol.NMR, 17, 2000
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1HZE
| SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF RIBOFLAVIN SYNTHASE FROM E. COLI | Descriptor: | RIBOFLAVIN, RIBOFLAVIN SYNTHASE ALPHA CHAIN | Authors: | Truffault, V, Coles, M, Diercks, T, Abelmann, K, Eberhardt, S, Luettgen, H, Bacher, A, Kessler, H. | Deposit date: | 2001-01-24 | Release date: | 2001-09-05 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The solution structure of the N-terminal domain of riboflavin synthase. J.Mol.Biol., 309, 2001
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1HR8
| Yeast Mitochondrial Processing Peptidase beta-E73Q Mutant Complexed with Cytochrome C Oxidase IV Signal Peptide | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CYTOCHROME C OXIDASE POLYPEPTIDE IV, MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT, ... | Authors: | Taylor, A.B, Smith, B.S, Kitada, S, Kojima, K, Miyaura, H, Otwinowski, Z, Ito, A, Deisenhofer, J. | Deposit date: | 2000-12-21 | Release date: | 2001-07-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences. Structure, 9, 2001
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3H9R
| Crystal structure of the kinase domain of type I activin receptor (ACVR1) in complex with FKBP12 and dorsomorphin | Descriptor: | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine, Activin receptor type-1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | Authors: | Chaikuad, A, Alfano, I, Shrestha, B, Muniz, J.R.C, Petrie, K, Fedorov, O, Phillips, C, Bishop, S, Mahajan, P, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC) | Deposit date: | 2009-04-30 | Release date: | 2009-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva. J.Biol.Chem., 287, 2012
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1HZF
| C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A | Descriptor: | COMPLEMENT FACTOR C4A | Authors: | van den Elsen, J.M.H, Martin, A, Wong, V, Clemenza, L, Rose, D.R, Isenman, D.E. | Deposit date: | 2001-01-24 | Release date: | 2002-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray crystal structure of the C4d fragment of human complement component C4. J.Mol.Biol., 322, 2002
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1QOL
| STRUCTURE OF THE FMDV LEADER PROTEASE | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, PROTEASE (NONSTRUCTURAL PROTEIN P20A) | Authors: | Guarne, A, Tormo, J, Kirchweger, R, Pfistermueller, D, Skern, T, Fita, I. | Deposit date: | 1999-11-13 | Release date: | 2000-11-10 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the Foot-and-Mouth Disease Virus Leader Protease: A Papain-Like Fold Adapted for Self-Processing and Eif4G Recognition. Embo J., 17, 1998
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1QQI
| SOLUTION STRUCTURE OF THE DNA-BINDING AND TRANSACTIVATION DOMAIN OF PHOB FROM ESCHERICHIA COLI | Descriptor: | PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB | Authors: | Okamura, H, Hanaoka, S, Nagadoi, A, Makino, K, Nishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 1999-06-07 | Release date: | 2000-06-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural comparison of the PhoB and OmpR DNA-binding/transactivation domains and the arrangement of PhoB molecules on the phosphate box. J.Mol.Biol., 295, 2000
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1QUQ
| COMPLEX OF REPLICATION PROTEIN A SUBUNITS RPA14 AND RPA32 | Descriptor: | PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT), PROTEIN (REPLICATION PROTEIN A 32 KD SUBUNIT) | Authors: | Bochkarev, A, Bochkareva, E, Frappier, L, Edwards, A.M. | Deposit date: | 1999-07-02 | Release date: | 1999-08-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding. EMBO J., 18, 1999
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1YFJ
| T4Dam in Complex with AdoHcy and 15-mer Oligonucleotide Showing Semi-specific and Specific Contact | Descriptor: | 5'-D(*TP*CP*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*TP*G)-3', CALCIUM ION, CHLORIDE ION, ... | Authors: | Horton, J.R, Liebert, K, Hattman, S, Jeltsch, A, Cheng, X. | Deposit date: | 2005-01-02 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase. Cell(Cambridge,Mass.), 121, 2005
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1QOJ
| Crystal Structure of E.coli UvrB C-terminal domain, and a model for UvrB-UvrC interaction. | Descriptor: | UVRB | Authors: | Sohi, M, Alexandrovich, A, Moolenaar, G, Visse, R, Goosen, N, Vernede, X, Fontecilla-Camps, J, Champness, J, Sanderson, M.R. | Deposit date: | 1999-11-10 | Release date: | 2000-11-10 | Last modified: | 2019-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of E.Coli Uvrb C-Terminal Domain, and a Model for Uvrb-Uvrc Interaction FEBS Lett., 465, 2000
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1PZU
| An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site | Descriptor: | 5'-D(*AP*AP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3', 5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3', Nuclear factor of activated T-cells, ... | Authors: | Jin, L, Sliz, P, Chen, L, Macian, F, Rao, A, Hogan, P.G, Harrison, S.C. | Deposit date: | 2003-07-14 | Release date: | 2003-09-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site Nat.Struct.Biol., 10, 2003
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1PM1
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2Q6B
| Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors | Descriptor: | (3R,5R)-7-[3-(4-FLUOROPHENYL)-1-ISOPROPYL-8-OXO-7-PHENYL-1,4,5,6,7,8-HEXAHYDROPYRROLO[2,3-C]AZEPIN-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | Authors: | Pavlovsky, A, Pfefferkorn, J.A, Harris, M.S, Finzel, B.C. | Deposit date: | 2007-06-04 | Release date: | 2007-07-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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1Z5X
| hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A | Descriptor: | 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, Ecdysone receptor ligand binding domain, PHOSPHATE ION, ... | Authors: | Carmichael, J.A, Lawrence, M.C, Graham, L.D, Pilling, P.A, Epa, V.C, Noyce, L, Lovrecz, G, Winkler, D.A, Pawlak-Skrzecz, A. | Deposit date: | 2005-03-21 | Release date: | 2005-04-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design. J.Biol.Chem., 280, 2005
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1ZP9
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1LVC
| Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 2' deoxy, 3' anthraniloyl ATP | Descriptor: | 3'ANTHRANILOYL-2'-DEOXY-ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, YTTERBIUM (III) ION, ... | Authors: | Shen, Y, Lee, Y.-S, Soelaiman, S, Bergson, P, Lu, D, Chen, A, Beckingham, K, Grabarek, Z, Mrksich, M, Tang, W.-J. | Deposit date: | 2002-05-28 | Release date: | 2002-12-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins Embo J., 21, 2002
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1PTK
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1Q18
| Crystal structure of E.coli glucokinase (Glk) | Descriptor: | Glucokinase | Authors: | Lunin, V.V, Li, Y, Schrag, J.D, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2003-07-18 | Release date: | 2004-07-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose. J.Bacteriol., 186, 2004
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1YST
| STRUCTURE OF THE PHOTOCHEMICAL REACTION CENTER OF A SPHEROIDENE CONTAINING PURPLE BACTERIUM, RHODOBACTER SPHAEROIDES Y, AT 3 ANGSTROMS RESOLUTION | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, MANGANESE (II) ION, ... | Authors: | Arnoux, B, Gaucher, J.F, Ducruix, A, Reiss-Husson, F. | Deposit date: | 1994-12-07 | Release date: | 1995-02-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the photochemical reaction centre of a spheroidene-containing purple-bacterium, Rhodobacter sphaeroides Y, at 3 A resolution. Acta Crystallogr.,Sect.D, 51, 1995
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