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6J73
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BU of 6j73 by Molmil
Crystal structure of IniA from Mycobacterium smegmatis
Descriptor: Isoniazid inducible gene protein IniA
Authors:Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H.
Deposit date:2019-01-16
Release date:2019-09-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.211 Å)
Cite:Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
4M5E
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BU of 4m5e by Molmil
Tse3 structure
Descriptor: CADMIUM ION, CALCIUM ION, GLYCEROL, ...
Authors:Qian, Y.
Deposit date:2013-08-08
Release date:2014-04-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
6LKA
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BU of 6lka by Molmil
Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds
Descriptor: 3C proteinase, ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide
Authors:Li, P, Wu, S.Q, Xiao, T.Y.C, Li, Y.L, Su, Z.M, Hao, F, Hu, G.P, Hu, J, Lin, F.S, Chen, X.S, Gu, Z.X, He, H.Y, Li, J, Chen, S.H.
Deposit date:2019-12-18
Release date:2020-06-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.033 Å)
Cite:Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent.
Bioorg.Med.Chem., 28, 2020
5E00
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BU of 5e00 by Molmil
Structure of HLA-A2 P130
Descriptor: Beta-2-microglobulin, GLY-VAL-TRP-ILE-ARG-THR-PRO-PRO-ALA, HLA class I histocompatibility antigen, ...
Authors:Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S.
Deposit date:2015-09-26
Release date:2017-01-18
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
8XJV
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BU of 8xjv by Molmil
Structural basis for the linker histone H5-nucleosome binding and chromatin compaction
Descriptor: DNA, Histone H2A, Histone H2B 1.1, ...
Authors:Li, W.Y, Song, F, Zhu, P.
Deposit date:2023-12-22
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for linker histone H5-nucleosome binding and chromatin fiber compaction.
Cell Res., 2024
7VRB
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BU of 7vrb by Molmil
Structure of the Human BRG1/SS18 complex
Descriptor: SMARCA4 protein,Protein SSXT
Authors:Cheng, Y, Chen, F, Zhou, H, Long, J.
Deposit date:2021-10-22
Release date:2022-05-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.389 Å)
Cite:Phase transition and remodeling complex assembly are important for SS18-SSX oncogenic activity in synovial sarcomas.
Nat Commun, 13, 2022
3NYL
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BU of 3nyl by Molmil
The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain
Descriptor: Amyloid beta (A4) protein (Peptidase nexin-II, Alzheimer disease), isoform CRA_b
Authors:Ha, Y, Hu, J, Lee, S, Liu, X, Wang, Y.
Deposit date:2010-07-15
Release date:2011-07-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain.
Mol.Cell, 15, 2004
6DG3
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BU of 6dg3 by Molmil
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with caesium
Descriptor: CESIUM ION, PHOSPHATE ION, Pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase
Authors:Fellner, M, Hausinger, R.P, Hu, J.
Deposit date:2018-05-16
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.944 Å)
Cite:Unique cesium-binding sites in proteins, a case study with the sacrificial sulfur transferase LarE
J Life Sci, 2021
7TUL
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BU of 7tul by Molmil
Woodchuck hepatitis small surface protein without cytosolic and antigenic loops
Descriptor: Large envelope protein
Authors:Liu, H, Wang, J.C.Y.
Deposit date:2022-02-02
Release date:2022-08-24
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Cryo-EM structures of human hepatitis B and woodchuck hepatitis virus small spherical subviral particles.
Sci Adv, 8, 2022
7TUK
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BU of 7tuk by Molmil
Small hepatitis B virus surface protein without cytosolic and antigenic loops
Descriptor: SAg protein
Authors:Liu, H, Wang, J.C.Y.
Deposit date:2022-02-02
Release date:2022-08-24
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Cryo-EM structures of human hepatitis B and woodchuck hepatitis virus small spherical subviral particles.
Sci Adv, 8, 2022
2AI6
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BU of 2ai6 by Molmil
Solution structure of human phosphohistidine phosphatase 1
Descriptor: 14 kDa phosphohistidine phosphatase
Authors:Gong, W, Cui, G, Jin, C, Xia, B.
Deposit date:2005-07-29
Release date:2006-10-17
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure and catalytic mechanism of human protein histidine phosphatase 1.
Biochem.J., 418, 2009
7VQQ
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BU of 7vqq by Molmil
Cryo-EM structure of amyloid fibril formed by FUS low complexity domain
Descriptor: fusion protein of mCerulean and FUS LCD
Authors:Sun, Y.P, Xia, W.C, Liu, C.
Deposit date:2021-10-20
Release date:2021-12-22
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular structure of an amyloid fibril formed by FUS low-complexity domain.
Iscience, 25, 2022
7V6P
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BU of 7v6p by Molmil
Crystal structure of human sNASP TPR domain
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Liu, C.P, Xu, R.M.
Deposit date:2021-08-20
Release date:2021-12-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones.
Genes Dev., 35, 2021
7V6Q
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BU of 7v6q by Molmil
Crystal structure of sNASP-ASF1A-H3.1-H4 complex
Descriptor: GLYCEROL, Histone H3.1, Histone H4, ...
Authors:Liu, C.P, Xu, R.M.
Deposit date:2021-08-20
Release date:2021-12-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones.
Genes Dev., 35, 2021
7VPN
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BU of 7vpn by Molmil
Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain in complex with Mn(II) and N-Oxalylglycine
Descriptor: CcTet molecule, MANGANESE (II) ION, N-OXALYLGLYCINE
Authors:Mu, Y.J, Zhang, L, Zhang, L.
Deposit date:2021-10-17
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA.
Nat.Chem.Biol., 18, 2022
8IYJ
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BU of 8iyj by Molmil
Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm
Descriptor: Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ...
Authors:Zhou, L.N, Gui, M, Wu, J.P.
Deposit date:2023-04-05
Release date:2023-07-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility.
Cell, 186, 2023
2OZX
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BU of 2ozx by Molmil
Solution structure of human phosphohistidine phosphatase 1 in phosphate free form
Descriptor: 14 kDa phosphohistidine phosphatase
Authors:Gong, W, Cui, G, Jin, C, Xia, B.
Deposit date:2007-02-27
Release date:2008-03-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and catalytic mechanism of human protein histidine phosphatase 1.
Biochem.J., 418, 2009
5HPS
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BU of 5hps by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1
Descriptor: Ubiquitin variant P1.1, WWP1 HECT
Authors:Wu, K.-P, Mercredi, P.Y, Schulman, B.A.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5HPK
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BU of 5hpk by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: NEDD4L and UbV NL.1
Descriptor: E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin variant NL.1
Authors:Wu, K.-P, Mukherjee, M, Mercredi, P.Y, Schulman, B.A.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.431 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5HPT
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BU of 5hpt by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1, Ubv P2.3 and UBCH7
Descriptor: NEDD4-like E3 ubiquitin-protein ligase WWP1, Ubiquitin variant P2.3, Ubiquitin-conjugating enzyme E2 L3
Authors:Wu, K.-P, Schulman, B.A.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5HPL
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BU of 5hpl by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: Rsp5 and UbV R5.4
Descriptor: Rsp5, Ubiquitin variant R5.4
Authors:Wu, K.-P, Kamadurai, H.B, Schulman, B.A.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
4X3O
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BU of 4x3o by Molmil
Sirt2 in complex with a myristoyl peptide
Descriptor: 1,2-ETHANEDIOL, NAD-dependent protein deacetylase sirtuin-2, ZINC ION, ...
Authors:Wang, Y, Zhang, W.Z, Hao, Q.
Deposit date:2014-12-01
Release date:2016-01-13
Last modified:2022-04-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure.
Cell Chem Biol, 24, 2017
4X3P
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BU of 4x3p by Molmil
Sirt2 in complex with a myristoyl peptide
Descriptor: 1,2-ETHANEDIOL, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NAD-dependent protein deacetylase sirtuin-2, ...
Authors:Wang, Y, Zhang, W, Hao, Q.
Deposit date:2014-12-01
Release date:2016-01-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure.
Cell Chem Biol, 24, 2017
5WSH
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BU of 5wsh by Molmil
Structure of HLA-A2 P130
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLY-VAL-TRP-ILE-ARG-THR-PRO-THR-ALA, ...
Authors:Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S.
Deposit date:2016-12-07
Release date:2017-12-20
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
6EW8
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BU of 6ew8 by Molmil
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
Descriptor: B-cell lymphoma 6 protein, CHLORIDE ION, anilinopyrimidine ligand
Authors:Robb, G, Ferguson, A, Hargreaves, D.
Deposit date:2017-11-03
Release date:2018-10-24
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018

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數據於2024-09-11公開中

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