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Crystal structure of Phosphoribosylaminoimidazole carboxylase catalytic subunit from Burkholderia cenocepacia J2315
Descriptor:	Phosphoribosylaminoimidazole carboxylase catalytic subunit
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-08-24
Release date:	2012-09-12
Last modified:	2024-05-29
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structure-Guided Discovery of N 5 -CAIR Mutase Inhibitors. Biochemistry, 62, 2023

4H4G

Crystal Structure of (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase from Burkholderia thailandensis E264
Descriptor:	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Authors:	Craig, T.K, Edwards, T.E, Staker, B, Stewart, L, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-09-17
Release date:	2012-10-03
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4H3E

Crystal structure of a putative iron superoxide dismutase from Trypanosoma cruzi bound to iron
Descriptor:	FE (II) ION, Superoxide dismutase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-09-13
Release date:	2012-09-26
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures. Acta Crystallogr F Struct Biol Commun, 71, 2015

4H3Z

Crystal structure of a symmetric dimer of a tRNA (guanine-(N(1)-)-methyltransferase from Burkholderia phymatum bound to S-adenosyl homocystein in both half-sites
Descriptor:	CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-09-14
Release date:	2012-10-03
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4HDT

Crystal structure of a Carnitinyl-CoA dehydratase from Mycobacterium thermoresistibile
Descriptor:	3-hydroxyisobutyryl-CoA hydrolase, ACETATE ION, CHLORIDE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-10-02
Release date:	2012-10-10
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4HEC

Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis
Descriptor:	MAGNESIUM ION, Putative uncharacterized protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-10-03
Release date:	2012-10-17
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Mycobacterium tuberculosis Rv2179c Protein Establishes a New Exoribonuclease Family with Broad Phylogenetic Distribution. J.Biol.Chem., 289, 2014

4GT1

Crystal structure of a MeaB- and MMAA-like GTPase from Mycobacterium tuberculosis bound to 2'-deoxyguanosine diphosphate
Descriptor:	2'-DEOXYGUANOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Probable GTPase Rv1496/MT1543, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-08-28
Release date:	2012-09-05
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structures of Mycobacterial MeaB and MMAA-like GTPases. J.Struct.Funct.Genom., 16, 2015

4HR3

Structure of a putative acyl-CoA dehydrogenase from Mycobacterium abscessus
Descriptor:	FLAVIN-ADENINE DINUCLEOTIDE, Putative acyl-CoA dehydrogenase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-10-26
Release date:	2012-11-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4I1Y

The structure of Cysteine synthase from Mycobacterium ulcerans Agy99
Descriptor:	CHLORIDE ION, Cysteine synthase, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-11-21
Release date:	2012-12-26
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4HVJ

Crystal structure of a putative uncharacterized protein from Mycobacterium tuberculosis in complex with AMP
Descriptor:	ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-11-06
Release date:	2012-11-28
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Mycobacterium tuberculosis Rv2179c Protein Establishes a New Exoribonuclease Family with Broad Phylogenetic Distribution. J.Biol.Chem., 289, 2014

4IJN

Crystal structure of an acetate kinase from Mycobacterium smegmatis bound to AMP and sulfate
Descriptor:	1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Acetate kinase, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-12-21
Release date:	2013-01-16
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4IUJ

Structure of Polymerase acid protein (PA) from Influenzavirus A Influenza A virus A, WILSON-SMITH/1933 (H1N1)
Descriptor:	Polymerase acidic protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-01-21
Release date:	2013-02-06
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1. Sci Rep, 4, 2014

4IV6

X-ray crystal structure of an isovaleryl-CoA dehydrogenase from Mycobacterium smegmatis
Descriptor:	Acyl-CoA dehydrogenase FadE3, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-01-22
Release date:	2013-03-20
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4IZ9

Crystal structure of an acetate kinase from Mycobacterium avium bound to an unknown acid-ApCpp conjugate and manganese
Descriptor:	1,2-ETHANEDIOL, Acetate kinase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-01-29
Release date:	2013-02-20
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.98 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4JF8

Crystal structure of a TrwG component of type IV secretion system protein from Bartonella birtlesii
Descriptor:	1,2-ETHANEDIOL, TrwG component of type IV secretion system
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-02-27
Release date:	2014-03-05
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.35 Å)
Cite:	Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. MBio, 6, 2015

4JV3

Crystal structure of beta-ketoacyl synthase from Brucella melitensis in complex with platencin
Descriptor:	2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid, Beta-ketoacyl synthase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-03-25
Release date:	2013-05-22
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites. Proteins, 88, 2020

4J5I

Crystal structure of an alpha-ketoglutarate-dependent taurine dioxygenase from Mycobacterium smegmatis
Descriptor:	1,2-ETHANEDIOL, Alpha-ketoglutarate-dependent taurine dioxygenase, FE (III) ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-02-08
Release date:	2013-02-20
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4KAM

X-ray crystal structure of O-acetylhomoserine sulfhydrylase MetC from Mycobacterium marinum ATCC BAA-535 / M
Descriptor:	O-acetylhomoserine sulfhydrylase MetC, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-04-22
Release date:	2013-05-01
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4KMS

Crystal structure of Acetoacetyl-CoA reductase from Rickettsia felis
Descriptor:	Acetoacetyl-CoA reductase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID), Abendroth, J, Lukacs, C, Edwards, T.E, Lorimer, D.
Deposit date:	2013-05-08
Release date:	2013-05-22
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis. Acta Crystallogr.,Sect.F, 77, 2021

4KZ1

Crystal structure of the soluble domain of VirB8 from Bartonella grahamii
Descriptor:	VirB8 protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-05-29
Release date:	2014-03-12
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.55 Å)
Cite:	Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. MBio, 6, 2015

4LGV

X-ray crystal structure of Glucose-6-phosphate 1-dehydrogenase from Mycobacterium avium
Descriptor:	1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-06-28
Release date:	2013-07-24
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4LSO

Crystal structure of the soluble domain of a Type IV secretion system protein VirB8 from Bartonella quintana Toulouse
Descriptor:	Type IV secretion system protein virB8
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-07-22
Release date:	2014-03-05
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. MBio, 6, 2015

3HGB

Crystal structure of glycine cleavage system protein H from Mycobacterium tuberculosis
Descriptor:	Glycine cleavage system H protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2009-05-13
Release date:	2009-05-26
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source. J.Struct.Funct.Genom., 11, 2010

3NFW

Crystal structure of nitrilotriacetate monooxygenase component B (A0R521 homolog) from Mycobacterium thermoresistibile
Descriptor:	Flavin reductase-like, FMN-binding protein, GLYCEROL
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-06-10
Release date:	2010-06-23
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Structure of nitrilotriacetate monooxygenase component B from Mycobacterium thermoresistibile. Acta Crystallogr.,Sect.F, 67, 2011

3NJB

Crystal structure of enoyl-coa hydratase from Mycobacterium smegmatis, iodide soak
Descriptor:	Enoyl-CoA hydratase, IODIDE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-06-17
Release date:	2010-07-28
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	SAD phasing using iodide ions in a high-throughput structural genomics environment. J.Struct.Funct.Genom., 12, 2011

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