4JV3
Crystal structure of beta-ketoacyl synthase from Brucella melitensis in complex with platencin
Summary for 4JV3
Entry DOI | 10.2210/pdb4jv3/pdb |
Related | 3LRF |
Descriptor | Beta-ketoacyl synthase, 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid (3 entities in total) |
Functional Keywords | ssgcid, beta-ketoacyl synthase, platencin, structural genomics, seattle structural genomics center for infectious disease, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Brucella melitensis biovar Abortus |
Total number of polymer chains | 1 |
Total formula weight | 46148.81 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2013-03-25, release date: 2013-05-22, Last modification date: 2023-09-20) |
Primary citation | Patterson, E.I.,Nanson, J.D.,Abendroth, J.,Bryan, C.,Sankaran, B.,Myler, P.J.,Forwood, J.K. Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites. Proteins, 88:47-56, 2020 Cited by PubMed: 31237717DOI: 10.1002/prot.25765 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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