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9B8Z
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BU of 9b8z by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and decavanadate at 37 degrees Celsius
Descriptor: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B92
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BU of 9b92 by Molmil
Cryo-EM structure of the human TRPM4 in complex with calcium at 18 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8W
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BU of 9b8w by Molmil
Cryo-EM structure of the human TRPM4 in complex with calcium at 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8X
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BU of 9b8x by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8Y
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BU of 9b8y by Molmil
Cryo-EM structure of the human TRPM4 channel in complex with calcium and decavanadate at 37 degrees Celsius
Descriptor: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B94
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BU of 9b94 by Molmil
Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-22
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B91
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BU of 9b91 by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B90
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BU of 9b90 by Molmil
Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
4E9A
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BU of 4e9a by Molmil
Structure of Peptide Deformylase form Helicobacter Pylori in complex with inhibitor
Descriptor: 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COBALT (II) ION, ...
Authors:Cui, K, Zhu, L, Lu, W, Huang, J.
Deposit date:2012-03-20
Release date:2013-04-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.662 Å)
Cite:Identification of Novel Peptide Deformylase Inhibitors from Natural Products
To be Published
4E9B
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BU of 4e9b by Molmil
Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACTINONIN, COBALT (II) ION, ...
Authors:Cui, K, Zhu, L, Lu, W, Huang, J.
Deposit date:2012-03-20
Release date:2013-04-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification of Novel Peptide Deformylase Inhibitors from Natural Products
To be Published
2NU3
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BU of 2nu3 by Molmil
Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
Descriptor: Ovomucoid, Streptogrisin B, Proteinase B
Authors:Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-11-08
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
2NU0
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BU of 2nu0 by Molmil
Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I, and Tyr18I
Descriptor: Ovomucoid, Streptogrisin B, Protease B
Authors:Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-11-08
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I, and Tyr18I
To be Published
2NU1
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BU of 2nu1 by Molmil
Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I
Descriptor: Ovomucoid, Streptogrisin B
Authors:Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-11-08
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I
To be Published
2NU4
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BU of 2nu4 by Molmil
Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
Descriptor: Ovomucoid, Streptogrisin B, Proteinase B
Authors:Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-11-08
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
2NU2
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BU of 2nu2 by Molmil
Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
Descriptor: Ovomucoid, Streptogrisin B, Protease B
Authors:Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
Deposit date:2006-11-08
Release date:2006-11-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
4PBX
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BU of 4pbx by Molmil
Crystal structure of the six N-terminal domains of human receptor protein tyrosine phosphatase sigma
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase S
Authors:Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R.
Deposit date:2014-04-14
Release date:2014-11-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
4PBW
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BU of 4pbw by Molmil
Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform
Authors:Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R.
Deposit date:2014-04-14
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
1ZMQ
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BU of 1zmq by Molmil
Crystal structure of human alpha-defensin-6
Descriptor: CHLORIDE ION, Defensin 6
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
4R7L
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BU of 4r7l by Molmil
Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1
Descriptor: ACETATE ION, GLYCEROL, IMIDAZOLE, ...
Authors:Ouyang, P, Cui, K, Lu, W, Huang, J.
Deposit date:2014-08-27
Release date:2015-11-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Human Leukotriene A4 Hydrolase in complex with SAHA
To be Published
1ZMP
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BU of 1zmp by Molmil
Crystal structure of human defensin-5
Descriptor: CHLORIDE ION, Defensin 5, GLYCEROL, ...
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
4PBV
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BU of 4pbv by Molmil
Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform, ...
Authors:Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R.
Deposit date:2014-04-14
Release date:2014-11-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
1ZMM
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BU of 1zmm by Molmil
Crystal structure of human alpha-defensin-4
Descriptor: Neutrophil defensin 4
Authors:Lubkowski, J, Szyk, A, Lu, W.
Deposit date:2005-05-10
Release date:2006-05-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
4TLL
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BU of 4tll by Molmil
Crystal structure of GluN1/GluN2B NMDA receptor, structure 1
Descriptor: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ...
Authors:Gouaux, E, Lee, C.-H, Lu, W.
Deposit date:2014-05-30
Release date:2014-07-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
4RVB
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BU of 4rvb by Molmil
Crystal Structure Analysis of the Human Leukotriene A4 Hydrolase
Descriptor: ACETATE ION, ACETIC ACID, GLYCEROL, ...
Authors:Ouyang, P, Lu, W, Cui, K, Huang, J.
Deposit date:2014-11-25
Release date:2015-12-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal Structure Analysis of the Human Leukotriene A4 Hydrolase
To be Published
4RSY
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BU of 4rsy by Molmil
Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7
Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, ACETIC ACID, IMIDAZOLE, ...
Authors:Ouyang, P, Lu, W, Cui, K, Huang, J.
Deposit date:2014-11-12
Release date:2015-12-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1
To be Published

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數據於2024-10-16公開中

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