1GUT
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1GYN
| Class II fructose 1,6-bisphosphate aldolase with Cadmium (not Zinc) in the active site | Descriptor: | CADMIUM ION, FRUCTOSE-BISPHOSPHATE ALDOLASE II | Authors: | Hall, D.R, Kemp, L.E, Leonard, G.A, Berry, A, Hunter, W.N. | Deposit date: | 2002-04-27 | Release date: | 2003-02-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Organization of Divalent Cations in the Active Site of Cadmium Escherichia Coli Fructose 1,6-Bisphosphate Aldolase Acta Crystallogr.,Sect.D, 59, 2003
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1H3M
| Structure of 4-diphosphocytidyl-2C-methyl-D-erythritol synthetase | Descriptor: | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLORIDE ION, PENTANE-1,5-DIAMINE | Authors: | Kemp, L.E, Bond, C.S, Hunter, W.N. | Deposit date: | 2002-09-10 | Release date: | 2003-08-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of a Tetragonal Crystal Form of Escherichia Coli 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase Acta Crystallogr.,Sect.D, 59, 2003
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1H48
| The structure of 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase in complex with CMP and product | Descriptor: | 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, 2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE, CYTIDINE-5'-MONOPHOSPHATE, ... | Authors: | Kemp, L.E, Alphey, M.S, Bond, C.S, Hunter, W.N. | Deposit date: | 2003-02-24 | Release date: | 2004-12-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods Acta Crystallogr.,Sect.D, 61, 2005
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1HH1
| THE STRUCTURE OF HJC, A HOLLIDAY JUNCTION RESOLVING ENZYME FROM SULFOLOBUS SOLFATARICUS | Descriptor: | HOLLIDAY JUNCTION RESOLVING ENZYME HJC | Authors: | Bond, C.S, Kvaratskhelia, M, Richard, D, White, M.F, Hunter, W.N. | Deposit date: | 2000-12-18 | Release date: | 2001-04-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of Hjc, a Holliday Junction Resolvase, from Sulfolobus Solfataricus Proc.Natl.Acad.Sci.USA, 98, 2001
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1GVF
| Structure of tagatose-1,6-bisphosphate aldolase | Descriptor: | 1,2-ETHANEDIOL, PHOSPHOGLYCOLOHYDROXAMIC ACID, SODIUM ION, ... | Authors: | Hall, D.R, Hunter, W.N. | Deposit date: | 2002-02-11 | Release date: | 2002-06-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of Tagatose-1,6-Bisphosphate Aldolase; Insight Into Chiral Discrimination, Mechanism and Specificity of Class II Aldolases J.Biol.Chem., 277, 2002
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2BFA
| Leishmania major pteridine reductase 1 in complex with NADP and CB3717 | Descriptor: | 1,2-ETHANEDIOL, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Schuettelkopf, A.W, Hunter, W.N. | Deposit date: | 2004-12-06 | Release date: | 2005-08-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of Leishmania Major Pteridine Reductase Complexes Reveal the Active Site Features Important for Ligand Binding and to Guide Inhibitor Design J.Mol.Biol., 352, 2005
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2AWH
| Human Nuclear Receptor-Ligand Complex 1 | Descriptor: | Peroxisome proliferator activated receptor delta, VACCENIC ACID, heptyl beta-D-glucopyranoside | Authors: | Fyffe, S.A, Alphey, M.S, Buetow, L, Smith, T.K, Ferguson, M.A.J, Sorensen, M.D, Bjorkling, F, Hunter, W.N. | Deposit date: | 2005-09-01 | Release date: | 2006-02-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Recombinant Human PPAR-beta/delta Ligand-binding Domain is Locked in an Activated Conformation by Endogenous Fatty Acids J.Mol.Biol., 356, 2006
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2B50
| Human Nuclear Receptor-Ligand Complex 2 | Descriptor: | CALCIUM ION, Peroxisome proliferator activated receptor delta, VACCENIC ACID, ... | Authors: | Fyffe, S.A, Alphey, M.S, Buetow, L, Smith, T.K, Ferguson, M.A.J, Sorensen, M.D, Bjorkling, F, Hunter, W.N. | Deposit date: | 2005-09-27 | Release date: | 2006-02-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Recombinant Human PPAR-beta/delta Ligand-binding Domain is Locked in an Activated Conformation by Endogenous Fatty Acids J.Mol.Biol., 356, 2006
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2AMT
| Structure of 2C-Methyl-D-Erythritol 2,4-Clycodiphosphate Synthase complexed with a CDP derived fluorescent inhibitor | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5'-O-[({[(2-{[(2-AMINOPHENYL)CARBONYL]OXY}ETHYL)OXY]PHOSPHINATO}OXY)PHOSPHINATO]CYTIDINE, GERANYL DIPHOSPHATE, ... | Authors: | Ramsden, N.L, Hunter, W.N. | Deposit date: | 2005-08-10 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Fluorescent Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy. Angew.Chem.Int.Ed.Engl., 45, 2006
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2BAW
| Human Nuclear Receptor-Ligand Complex 1 | Descriptor: | Peroxisome proliferator activated receptor delta, VACCENIC ACID, heptyl beta-D-glucopyranoside | Authors: | Fyffe, S.A, Alphey, M.S, Buetow, L, Smith, T.K, Ferguson, M.A.J, Sorensen, M.D, Bjorkling, F, Hunter, W.N. | Deposit date: | 2005-10-15 | Release date: | 2006-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Reevaluation of the PPAR-beta/delta Ligand Binding Domain Model Reveals Why It Exhibits the Activated Form Mol.Cell, 21, 2006
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2CNB
| Trypanosoma brucei UDP-galactose-4-epimerase in ternary complex with NAD and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-GALACTOSE-4-EPIMERASE, URIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE | Authors: | Alphey, M.S, Ferguson, M.A.J, Hunter, W.N. | Deposit date: | 2006-05-18 | Release date: | 2006-06-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Trypanosoma Brucei Udp-Galactose-4-Epimerase in Ternary Complex with Nad+ and the Substrate Analogue Udp-4-Deoxy-4-Fluoro-Alpha-D-Galactose Acta Crystallogr.,Sect.F, 62, 2006
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2F51
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1OJ4
| Ternary complex of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLORIDE ION, ... | Authors: | Miallau, L, Alphey, M.S, Hunter, W.N. | Deposit date: | 2003-06-30 | Release date: | 2003-07-31 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase Proc.Natl.Acad.Sci.USA, 100, 2003
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1NP6
| Crystal structure of Escherichia coli MobB | Descriptor: | Molybdopterin-guanine dinucleotide biosynthesis protein B, SULFATE ION | Authors: | McLuskey, K, Harrison, J.A, Schuttelkopf, A.W, Boxer, D.H, Hunter, W.N. | Deposit date: | 2003-01-17 | Release date: | 2003-04-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insight into the role of Escherichia coli MobB in Molybdenum cofactor biosynthesis based on the high resolution crystal structure J.Biol.Chem., 278, 2003
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1O6J
| Tryparedoxin II from C.fasciculata solved by sulphur phasing | Descriptor: | TRYPAREDOXIN II | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | Deposit date: | 2002-10-04 | Release date: | 2002-11-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | De Novo Phasing of Two Crystal Forms of Tryparedoxin II Using the Anomalous Scattering from S Atoms: A Combination of Small Signal and Medium Resolution Reveals This to be a General Tool for Solving Protein Crystal Structures Acta Crystallogr.,Sect.D, 58, 2002
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1OKG
| 3-mercaptopyruvate sulfurtransferase from Leishmania major | Descriptor: | CALCIUM ION, POSSIBLE 3-MERCAPTOPYRUVATE SULFURTRANSFERASE, SULFITE ION | Authors: | Alphey, M.S, Hunter, W.N. | Deposit date: | 2003-07-24 | Release date: | 2003-09-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of Leishmania Major 3-Mercaptopyruvate Sulfurtransferase: A Three-Domain Architecture with a Serine Protease-Like Triad at the Active Site J.Biol.Chem., 278, 2003
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1QK8
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1O73
| Tryparedoxin from Trypanosoma brucei | Descriptor: | TRYPAREDOXIN | Authors: | Gabrielsen, M, Alphey, M.S, Bond, C.S, Hunter, W.N. | Deposit date: | 2002-10-23 | Release date: | 2003-04-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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1OC9
| TRYPAREDOXIN II FROM C.FASCICULATA solved by MR | Descriptor: | TRYPAREDOXIN II | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | Deposit date: | 2003-02-07 | Release date: | 2003-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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1O7L
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1OC8
| TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY MR | Descriptor: | SULFATE ION, TRYPAREDOXIN II | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | Deposit date: | 2003-02-07 | Release date: | 2003-04-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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1QNH
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1O81
| Tryparedoxin II from C.fasciculata solved by sulphur phasing | Descriptor: | SULFATE ION, TRYPAREDOXIN II | Authors: | Leonard, G.A, Micossi, E, Hunter, W.N. | Deposit date: | 2002-11-21 | Release date: | 2002-12-19 | Last modified: | 2019-10-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | De Novo Phasing of Two Crystal Forms of Tryparedoxin II Using the Anomalous Scattering from S Atoms: A Combination of Small Signal and Medium Resolution Reveals This to be a General Tool for Solving Protein Crystal Structures Acta Crystallogr.,Sect.D, 58, 2002
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1QNG
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