2CNB

Trypanosoma brucei UDP-galactose-4-epimerase in ternary complex with NAD and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose

Summary for 2CNB

• Entry DOI: 10.2210/pdb2cnb/pdb
• Related: 1GY8
• Descriptor: UDP-GALACTOSE-4-EPIMERASE, URIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• Functional Keywords: epimerase, short-chain dehydrogenase/reductase, udp-galactose-4- epimerase, nad, isomerase, trypanosoma brucei, udp-4-deoxy- 4-fluoro-alpha-d-galactose
• Biological source: TRYPANOSOMA BRUCEI
• Total number of polymer chains: 4
• Total formula weight: 180153.06

Authors

Alphey, M.S.,Ferguson, M.A.J.,Hunter, W.N. (deposition date: 2006-05-18, release date: 2006-06-12, Last modification date: 2011-07-13)

• Primary citation: Alphey, M.S.,Burton, A.,Urbaniak, M.,Boons, G.J.,Ferguson, M.A.J.,Hunter, W.N.; Trypanosoma Brucei Udp-Galactose-4-Epimerase in Ternary Complex with Nad+ and the Substrate Analogue Udp-4-Deoxy-4-Fluoro-Alpha-D-Galactose; Acta Crystallogr.,Sect.F, 62:829-, 2006; PubMed: 16946458; DOI: 10.1107/S1744309106028740

Experimental method

X-RAY DIFFRACTION (2.7 Å)