8HEN
| Crystal structure of CTSB in complex with 212-148 | Descriptor: | 2-[4-[[(2~{S})-1-oxidanylidene-3-phenyl-1-[[(3~{S})-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]amino]propan-2-yl]carbamoyl]piperazin-1-yl]ethyl 4-carbamimidamidobenzoate, Cathepsin B, DIMETHYL SULFOXIDE, ... | Authors: | Wang, H, Li, D, Sun, L, Yang, H. | Deposit date: | 2022-11-08 | Release date: | 2023-12-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
|
|
3PFN
| Crystal Structure of human NAD kinase | Descriptor: | NAD kinase, UNKNOWN ATOM OR ION | Authors: | Wang, H, Tempel, W, Wernimont, A.K, Tong, Y, Guan, X, Shen, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-10-28 | Release date: | 2010-11-10 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of human NAD kinase to be published
|
|
3Q3J
| Crystal structure of plexin A2 RBD in complex with Rnd1 | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-A2, ... | Authors: | Wang, H, Tempel, W, Tong, Y, Guan, X, Shen, L, Buren, L, Zhang, N, Wernimont, A.K, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-12-21 | Release date: | 2011-01-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.971 Å) | Cite: | Crystal structure of plexin A2 RBD in complex with Rnd1 to be published
|
|
8JJ1
| Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab2G7 in two fab conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2G7 Heavy Chain, ... | Authors: | Wang, H, Zhu, S. | Deposit date: | 2023-05-29 | Release date: | 2024-06-05 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024
|
|
8JIZ
| |
8JJ2
| Cryo-EM structure of GluN1-2A NMDAR in complex with human Fab2G7 in one fab conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab2G7 Heavy Chain, ... | Authors: | Wang, H, Zhu, S. | Deposit date: | 2023-05-29 | Release date: | 2024-06-05 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024
|
|
8JJ0
| |
4ED5
| Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA | Descriptor: | 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ... | Authors: | Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X. | Deposit date: | 2012-03-27 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding. Acta Crystallogr.,Sect.D, 69, 2013
|
|
2PW3
| Structure of the PDE4D-cAMP complex | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ZINC ION, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Authors: | Wang, H, Robinson, H, Ke, H. | Deposit date: | 2007-05-10 | Release date: | 2007-10-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10. J.Mol.Biol., 371, 2007
|
|
1WWS
| Crystal structure of ttk003001566 from Thermus Thermophilus HB8 | Descriptor: | CALCIUM ION, hypothetical protein TTHA1479 | Authors: | Wang, H, Murayama, K, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-01-18 | Release date: | 2006-01-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of ttk003001566 from Thermus Thermophilus HB8 to be published
|
|
1WDT
| Crystal structure of ttk003000868 from Thermus thermophilus HB8 | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, elongation factor G homolog | Authors: | Wang, H, Takemoto-Hori, C, Murayama, K, Sekine, S, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-17 | Release date: | 2005-05-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of ttk003000868 from Thermus thermophilus HB8 To be published
|
|
4MM7
| |
4MMC
| |
4MMD
| |
4MM8
| |
4MMF
| Crystal structure of LeuBAT (delta5 mutant) in complex with mazindol | Descriptor: | (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ... | Authors: | Wang, H, Gouaux, E. | Deposit date: | 2013-09-08 | Release date: | 2013-10-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
|
|
4MM4
| |
4MM9
| |
4MM5
| Crystal structure of LeuBAT (delta13 mutant) in complex with sertraline | Descriptor: | (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, SODIUM ION, Transporter | Authors: | Wang, H, Gouaux, E. | Deposit date: | 2013-09-08 | Release date: | 2013-10-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
|
|
4MMB
| Crystal structure of LeuBAT (delta6 mutant) in complex with sertraline | Descriptor: | (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, SODIUM ION, Transporter, ... | Authors: | Wang, H, Gouaux, E. | Deposit date: | 2013-09-08 | Release date: | 2013-10-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
|
|
4MMA
| |
2QYK
| Crystal structure of PDE4A10 in complex with inhibitor NPV | Descriptor: | 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid, Cyclic AMP-specific phosphodiesterase HSPDE4A10, MAGNESIUM ION, ... | Authors: | Wang, H, Peng, M, Chen, Y, Geng, J, Robinson, H, Houslay, M. | Deposit date: | 2007-08-15 | Release date: | 2008-04-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors. Biochem.J., 408, 2007
|
|
4MM6
| |
4MME
| Crystal structure of LeuBAT (delta6 mutant) in complex with mazindol | Descriptor: | (5R)-5-(4-chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol, SODIUM ION, Transporter, ... | Authors: | Wang, H, Gouaux, E. | Deposit date: | 2013-09-08 | Release date: | 2013-10-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503, 2013
|
|
1WWP
| Crystal structure of ttk003001694 from Thermus Thermophilus HB8 | Descriptor: | hypothetical protein TTHA0636 | Authors: | Wang, H, Murayama, K, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-01-12 | Release date: | 2005-07-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal structure of ttk003001694 from Thermus Thermophilus HB8 TO BE PUBLISHED
|
|