2R8Q
Structure of LmjPDEB1 in complex with IBMX
Summary for 2R8Q
Entry DOI | 10.2210/pdb2r8q/pdb |
Descriptor | Class I phosphodiesterase PDEB1, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | leishimaniasis, parasite inhibitor selectivity, camp phosphodiesterase, hydrolase |
Biological source | Leishmania major |
Total number of polymer chains | 2 |
Total formula weight | 81751.76 |
Authors | |
Primary citation | Wang, H.,Yan, Z.,Geng, J.,Kunz, S.,Seebeck, T.,Ke, H. Crystal structure of the Leishmania major phosphodiesterase LmjPDEB1 and insight into the design of the parasite-selective inhibitors. Mol.Microbiol., 66:1029-1038, 2007 Cited by PubMed: 17944832DOI: 10.1111/j.1365-2958.2007.05976.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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